Age peculiarities in the effect of stimulation of α2-adrenergic receptor on electrical activity of rat cardiomyocytes

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Clonidine hydrochloride, an agonist of the α2-adrenergic receptor, was tested for its effect on the parameters of the electrical activity of the atrial myocardium induced by pacing. In the experimental rat cardiomyocyte pacing model, clonidine hydrochloride caused a decrease (approximately 50% and 90%) in action potential duration in adult rats. Treatment of one- and three-week-old rats with this agonist led to an increase (around 50% and 90%) in action potential duration

作者简介

A. Galieva

Kazan Federal University

Email: galieva_alina94@mail.ru
Kazan, Russia

N. Ziyatdinova

Kazan Federal University

Kazan, Russia

N. Mansour

Kazan Federal University

Kazan, Russia

L. Fashutdinov

Kazan Federal University

Kazan, Russia

T. Zefirov

Kazan Federal University

Kazan, Russia

参考

  1. B. Bylund, D. C. Eikenberg, J. P. Hieble, et al., Pharmacol. Rev., 46, 121 (1994).
  2. M. Philipp and L. Hein, Pharmacol. Ther., 101, 65 (2004).
  3. W. Hoefke and W. Kobinger, Arzneimittelforschung, 16, 1038 (1966).
  4. R. D. Sanders and M. Maze Adrenergic and cholinergic compounds. In Handbook of experimental pharmacology, Vol. 177. Analgesia, Ed. by C. Stein (Springer, Heidelberg, 2007), pp. 251-264.
  5. R. Gilsbach, J. Albarran-Juarez, and L. Hein, Curr. Topics in Membranes, 67, 139 (2011).
  6. O.-E. Brodde and M. C. Michel, Pharmacol. Rev., 51, 651 (1999).
  7. S. Minatoguchi, H. Ito, K. Ishimura, et al., Am. Heart J., 130, 516 (1995).
  8. O.-E. Brodde, H. Bruck, and K. Leineweber, J. Pharmacol. Sci., 100, 323 (2006).
  9. K. Starke, J. Neurochem., 78, 685 (2001).
  10. A. U. Trendelenburg, W. Klebroff, L. Hein, and K. Starke, Naunyn-Schmiedeberg's Arch. Pharmacol., 364 (2), 117 (2001).
  11. J. Lahdesmaki, J. Sallinen, E. MacDonald, et al., Neuroscience, 113 (2), 289 (2002). doi: 10.1016/S0306-4522(02)00185-9
  12. M. Brede, G. Nagy, M. Philipp, et al., Mol. Endocrinol., 17 (8), 1640 (2003).
  13. R. Gilsbach, J. Schneider, A. Lother, et al., Cardiovasc. Res., 86 (3), 432 (2010).
  14. Y. Yoshikawa, N. Hirata, R. Kawaguchi, et al, Anesthesia & Analgesia, 126 (2), 443 (2018).
  15. B.-E. Myagmar, J. M. Flynn, P. M. Cowley, et al., Circ. Res., 120 (7), 1103 (2017).
  16. M. Hongo, S. Fujisawa, T. Adachi, et al., J. Pharmacol. Sci., 131 (2), 118 (2016).
  17. W. Lorenz, J. W. Lomasney, S. Collins, et al., Mol. Pharmacol., 38 (5), 599 (1990).
  18. M. Ibacache, G. Sanchez, Z. Pedrozo, et al., Biochim. Biophys. Acta - Molecular Basis of Disease, 1822 (4), 537 (2012).
  19. D. E. Berkowitz, D. T. Price, E. A. Bello, et al., J. Am. Soc. Anesthesiol., 81 (5), 1235 (1994).
  20. Y. M. Kokoz, E. V. Evdokimovskii, A. V. Maltsev, et al., J. Mol. Cell. Cardiol., 100, 9 (2016).
  21. A. Martinez-Fernandez, T. J. Nelson, S. Reyes, et al., Circulation. Cardiovasc. Genetics, 7 (5), 667 (2014).
  22. A. E. Alekseev, S. Park, O. Y. Pimenov, et al., Pharmacol. Therapeut., 197, 179 (2019).
  23. A. A. Zverev, T. A. Anikina, N. G. Iskakov, et al., Bull. Exp. Biol. Med., 165 (5), 610 (2018).
  24. А. М. Купцова, И. И. Хабибрахманов, А. М. Галиева и др., в Сб. тезисов III Международного конгресса "Фундаментальная и клиническая электрофизиология. Актуальные вопросы аритмологии" (2019), сс. 65-66.
  25. Л. И. Фасхутдинов, Н. И. Зиятдинова, Р. С. Кобзарев и Т. Л. Зефиров, Рос. кардиол. журн., № 27 (S5), 113 2022.
  26. Ф. Г. Ситдиков и Т. Л. Зефиров, Лекции по возрастной физиологии сердца (ТГГПУ, Казань, 2006).
  27. С. А. Кодиров, В. Л. Журавлев, Т. А. Сафонова и др., Обзоры по клинич. и лекарств. фармакологии 3 (4), 27 (2004).
  28. C. M. J. Tan, P. Green, N. Tapoulal, et al., Front. Physiol., 9, 1 (2018).

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