Molecular mechanisms mediating involvement of glial cells in brain plastic remodeling in epilepsy
- 作者: Khaspekov L.1, Frumkina L.1
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隶属关系:
- Department of Brain Research
- 期: 卷 82, 编号 3 (2017)
- 页面: 380-391
- 栏目: Review
- URL: https://journals.rcsi.science/0006-2979/article/view/151313
- DOI: https://doi.org/10.1134/S0006297917030178
- ID: 151313
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详细
In this review we summarize published data on the involvement of glial cells in molecular mechanisms underlying brain plastic reorganization in epilepsy. The role of astrocytes as glial elements in pathological plasticity in epilepsy is discussed. Data on the involvement of aquaporin-4 in epileptogenic plastic changes and on participation of microglia and extracellular matrix in dysregulation of synaptic transmission and plastic remodeling in epileptic brain tissue are reviewed.
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作者简介
L. Khaspekov
Department of Brain Research
编辑信件的主要联系方式.
Email: khaspekleon@mail.ru
俄罗斯联邦, Moscow, 105064
L. Frumkina
Department of Brain Research
Email: khaspekleon@mail.ru
俄罗斯联邦, Moscow, 105064