The role of cytokines in the development of atherosclerosis
- 作者: Fatkhullina A.1, Peshkova I.1, Koltsova E.1
-
隶属关系:
- Fox Chase Cancer Center
- 期: 卷 81, 编号 11 (2016)
- 页面: 1358-1370
- 栏目: Review
- URL: https://journals.rcsi.science/0006-2979/article/view/151106
- DOI: https://doi.org/10.1134/S0006297916110134
- ID: 151106
如何引用文章
详细
Atherosclerosis contributes to the development of many cardiovascular diseases, which remain the leading cause of death in developed countries. Atherosclerosis is a chronic inflammatory disease of large and medium-sized arteries. It is caused by dyslipidemia and mediated by both innate and adaptive immune responses. Inflammation is a key factor at all stages of atherosclerosis progression. Cells involved in pathogenesis of atherosclerosis were shown to be activated by soluble factors, cytokines, that strongly influence the disease development. Pro-inflammatory cytokines accelerate atherosclerosis progression, while anti-inflammatory cytokines ameliorate the disease. In this review, we discuss the latest findings on the role of cytokines in the development and progression of atherosclerosis.
作者简介
A. Fatkhullina
Fox Chase Cancer Center
Email: Ekaterina.Koltsova@fccc.edu
美国, 333 Cottman Avenue, Philadelphia, PA
I. Peshkova
Fox Chase Cancer Center
Email: Ekaterina.Koltsova@fccc.edu
美国, 333 Cottman Avenue, Philadelphia, PA
E. Koltsova
Fox Chase Cancer Center
编辑信件的主要联系方式.
Email: Ekaterina.Koltsova@fccc.edu
美国, 333 Cottman Avenue, Philadelphia, PA
![](/img/style/loading.gif)