Interaction between Saccharomyces cerevisiae mitochondrial DNA-binding protein Abf2p and Cce1p resolvase
- 作者: Samoilova E.1, Krasheninnikov I.1, Levitskii S.1
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隶属关系:
- Faculty of Biology
- 期: 卷 81, 编号 10 (2016)
- 页面: 1111-1117
- 栏目: Article
- URL: https://journals.rcsi.science/0006-2979/article/view/151036
- DOI: https://doi.org/10.1134/S0006297916100096
- ID: 151036
如何引用文章
详细
Mitochondrial DNA is susceptible to the action of reactive oxygen species generated by the reactions of oxidative phosphorylation. Homologous recombination is one of the mechanisms providing integrity of the mitochondrial genome. Some proteins that take part in this process in budding yeast mitochondria have been identified. These include Abf2p, the major protein of the mt-nucleoid that specifically binds cruciform DNA, and Cce1p – Holliday junction resolvase. Here we show that Abf2p does not significantly affect either binding of Cce1p to branched DNA or rate and specificity of Holliday junction resolution. These data suggest the existence of an alternative homologous recombination pathway in yeast mitochondria.
作者简介
E. Samoilova
Faculty of Biology
Email: krolick@yandex.ru
俄罗斯联邦, 119991, Moscow
I. Krasheninnikov
Faculty of Biology
Email: krolick@yandex.ru
俄罗斯联邦, 119991, Moscow
S. Levitskii
Faculty of Biology
编辑信件的主要联系方式.
Email: krolick@yandex.ru
俄罗斯联邦, 119991, Moscow
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