Отправить статью по E-mail Inorganic Polyphosphate and Cancer
- Авторы: Kulakovskaya E.1, Zemskova M.1,2, Kulakovskaya T.1
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Учреждения:
- Skryabin Institute of Biochemistry and Physiology of Microorganisms
- Moscow State Regional University
- Выпуск: Том 83, № 8 (2018)
- Страницы: 961-968
- Раздел: Mini-Review
- URL: https://journals.rcsi.science/0006-2979/article/view/151701
- DOI: https://doi.org/10.1134/S0006297918080072
- ID: 151701
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Аннотация
This review presents data on the relationship between inorganic polyphosphate metabolism and carcinogenesis including participation of polyphosphates in the regulation of activity of mTOR and other proteins involved in carcinogenesis, the role of h-prune protein (human polyphosphatase) in cell migration and metastasis formation, the prospects for using polyphosphates and inhibitors of polyphosphate metabolism enzymes as agents for controlling cell proliferation and migration.
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Об авторах
E. Kulakovskaya
Skryabin Institute of Biochemistry and Physiology of Microorganisms
Email: alla@ibpm.pushchino.ru
Россия, Pushchino, Moscow Region, 142290
M. Zemskova
Skryabin Institute of Biochemistry and Physiology of Microorganisms; Moscow State Regional University
Email: alla@ibpm.pushchino.ru
Россия, Pushchino, Moscow Region, 142290; Pushchino, Moscow Region, 142290
T. Kulakovskaya
Skryabin Institute of Biochemistry and Physiology of Microorganisms
Автор, ответственный за переписку.
Email: alla@ibpm.pushchino.ru
Россия, Pushchino, Moscow Region, 142290
