Investigations of Photosensitive Proteins by Serial Crystallography
- Авторы: Selikhanov G.1, Fando M.1, Dontsova M.1, Gabdulkhakov A.1
-
Учреждения:
- Institute of Protein Research
- Выпуск: Том 83, № 1 (2018): Suppl
- Страницы: S163-S175
- Раздел: Review
- URL: https://journals.rcsi.science/0006-2979/article/view/151589
- DOI: https://doi.org/10.1134/S0006297918140134
- ID: 151589
Цитировать
Аннотация
This review contains recent data on serial femtosecond X-ray crystallography (SFX), based on a femtosecond X-ray free electron laser, as well as on the possibilities of its application for studying photosensitive proteins. Development of this method began rather recently, and it has already shown its effectiveness and some unique advantages over conventional X-ray structural analysis. This technology is especially promising for structural studies of membrane proteins and for kinetic studies. The main principle of the method, the possibility of its application in structural biology, its advantages and disadvantages, as well as its prospects for further development are analyzed in this review. Special attention is given to publications in which the SFX method has been used to study photosensitive proteins.
Ключевые слова
Об авторах
G. Selikhanov
Institute of Protein Research
Email: azat@vega.protres.ru
Россия, Pushchino, Moscow Region, 142290
M. Fando
Institute of Protein Research
Email: azat@vega.protres.ru
Россия, Pushchino, Moscow Region, 142290
M. Dontsova
Institute of Protein Research
Email: azat@vega.protres.ru
Россия, Pushchino, Moscow Region, 142290
A. Gabdulkhakov
Institute of Protein Research
Автор, ответственный за переписку.
Email: azat@vega.protres.ru
Россия, Pushchino, Moscow Region, 142290
![](/img/style/loading.gif)