Structure of the K82 Capsular Polysaccharide from Acinetobacter baumannii LUH5534 Containing a d-Galactose 4,6-Pyruvic Acid Acetal
- Autores: Kasimova A.1,2, Kenyon J.3,4, Arbatsky N.1, Shashkov A.1, Popova A.5,6, Knirel Y.1, Hall R.3,7
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Afiliações:
- Zelinsky Institute of Organic Chemistry
- Higher Chemical College of the Russian Academy of Sciences
- School of Molecular Bioscience
- Institute of Health and Biomedical Innovation, School of Biomedical Sciences, Faculty of Health
- Moscow Institute of Physics and Technology
- State Research Center for Applied Microbiology and Biotechnology
- School of Life and Environmental Sciences
- Edição: Volume 83, Nº 7 (2018)
- Páginas: 831-835
- Seção: Article
- URL: https://journals.rcsi.science/0006-2979/article/view/151688
- DOI: https://doi.org/10.1134/S0006297918070064
- ID: 151688
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Resumo
Type K82 capsular polysaccharide (CPS) was isolated from Acinetobacter baumannii LUH5534. The structure of a linear tetrasaccharide repeating unit of the CPS was established by sugar analysis along with one- and two-dimensional 1H and 13C NMR spectroscopy. Proteins encoded by the KL82 capsule gene cluster in the genome of LUH5534 were assigned to roles in the synthesis of the K82 CPS. In particular, functions were assigned to two new glycosyltransferases (Gtr152 and Gtr153) and a novel pyruvyltransferase, Ptr5, responsible for the synthesis of D-galactose 4,6-(R)-pyruvic acid acetal.
Sobre autores
A. Kasimova
Zelinsky Institute of Organic Chemistry; Higher Chemical College of the Russian Academy of Sciences
Autor responsável pela correspondência
Email: nastia-kasimova979797@mail.ru
Rússia, Moscow, 119991; Moscow, 125047
J. Kenyon
School of Molecular Bioscience; Institute of Health and Biomedical Innovation, School of Biomedical Sciences, Faculty of Health
Email: nastia-kasimova979797@mail.ru
Austrália, Sydney, NSW, 2006; Brisbane, QLD, 4059
N. Arbatsky
Zelinsky Institute of Organic Chemistry
Email: nastia-kasimova979797@mail.ru
Rússia, Moscow, 119991
A. Shashkov
Zelinsky Institute of Organic Chemistry
Email: nastia-kasimova979797@mail.ru
Rússia, Moscow, 119991
A. Popova
Moscow Institute of Physics and Technology; State Research Center for Applied Microbiology and Biotechnology
Email: nastia-kasimova979797@mail.ru
Rússia, Dolgoprudny, Moscow Region, 141700; Obolensk, Moscow Region, 142279
Y. Knirel
Zelinsky Institute of Organic Chemistry
Email: nastia-kasimova979797@mail.ru
Rússia, Moscow, 119991
R. Hall
School of Molecular Bioscience; School of Life and Environmental Sciences
Email: nastia-kasimova979797@mail.ru
Austrália, Sydney, NSW, 2006; Sydney, NSW, 2006
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