Features of gene expression of Bacillus pumilus metalloendopeptidase
- Autores: Rudakova N.1, Sabirova A.1, Balaban N.1, Tikhonova A.1, Sharipova M.1
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Afiliações:
- Kazan (Volga Region) Federal University
- Edição: Volume 81, Nº 8 (2016)
- Páginas: 884-891
- Seção: Article
- URL: https://journals.rcsi.science/0006-2979/article/view/150983
- DOI: https://doi.org/10.1134/S0006297916080095
- ID: 150983
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Resumo
Features of gene expression of the secreted Bacillus pumilus metalloendopeptidase belonging to the adamalysin/reprolysin family were investigated. In the regulatory region of the gene, we identified hypothetical binding sites for transcription factors CcpA and TnrA. We found that the expression of the metalloendopeptidase gene is controlled by mechanisms of carbon and nitrogen catabolite repression. In experiments involving nitrogen metabolism regulatory protein mutant strains, we found that the control of the metalloendopeptidase gene expression involves proteins of ammonium transport GlnK and AmtB interacting with the TnrA-regulator.
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Sobre autores
N. Rudakova
Kazan (Volga Region) Federal University
Autor responsável pela correspondência
Email: natalialrudakova@mail.ru
Rússia, Kazan, 420008
A. Sabirova
Kazan (Volga Region) Federal University
Email: natalialrudakova@mail.ru
Rússia, Kazan, 420008
N. Balaban
Kazan (Volga Region) Federal University
Email: natalialrudakova@mail.ru
Rússia, Kazan, 420008
A. Tikhonova
Kazan (Volga Region) Federal University
Email: natalialrudakova@mail.ru
Rússia, Kazan, 420008
M. Sharipova
Kazan (Volga Region) Federal University
Email: natalialrudakova@mail.ru
Rússia, Kazan, 420008
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