Mobility of Nuclear Components and Genome Functioning


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Abstract

Cell nucleus is characterized by strong compartmentalization of structural components in its three-dimensional space. Certain genomic functions are accompanied by changes in the localization of chromatin loci and nuclear bodies. Here we review recent data on the mobility of nuclear components and the role of this mobility in genome functioning.

About the authors

E. A. Arifulin

Belozersky Institute of Physico-Chemical Biology

Author for correspondence.
Email: lewanit@gmail.com
Russian Federation, Moscow, 119991

Y. R. Musinova

Belozersky Institute of Physico-Chemical Biology; LIA 1066 LFR2O French-Russian Joint Cancer Research Laboratory; Koltzov Institute of Developmental Biology

Email: lewanit@gmail.com
Russian Federation, Moscow, 119991; Villejuif, 94805; Moscow, 119334

Y. S. Vassetzky

Belozersky Institute of Physico-Chemical Biology; LIA 1066 LFR2O French-Russian Joint Cancer Research Laboratory; Koltzov Institute of Developmental Biology; UMR8126, CNRS, Université Paris-Sud

Email: lewanit@gmail.com
Russian Federation, Moscow, 119991; Villejuif, 94805; Moscow, 119334; Villejuif, 94805

E. V. Sheval

Belozersky Institute of Physico-Chemical Biology; LIA 1066 LFR2O French-Russian Joint Cancer Research Laboratory

Email: lewanit@gmail.com
Russian Federation, Moscow, 119991; Villejuif, 94805


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