Email this article Role of Nuclear Lamina in Gene Repression and Maintenance of Chromosome Architecture in the Nucleus
- Authors: Shevelyov Y.Y.1, Ulianov S.V.2,3
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Affiliations:
- Institute of Molecular Genetics
- Institute of Gene Biology
- Lomonosov Moscow State University
- Issue: Vol 83, No 4 (2018)
- Pages: 359-369
- Section: Review
- URL: https://journals.rcsi.science/0006-2979/article/view/151629
- DOI: https://doi.org/10.1134/S0006297918040077
- ID: 151629
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Abstract
Nuclear lamina is a protein meshwork composed of lamins and lamin-associated proteins that lines the nuclear envelope from the inside and forms repressive transcription compartment. The review presents current data on the contribution of nuclear lamina to the repression of genes located in this compartment and on the mechanisms of chromatin attachment to the nuclear envelope.
About the authors
Y. Y. Shevelyov
Institute of Molecular Genetics
Author for correspondence.
Email: shevelev@img.ras.ru
Russian Federation, Moscow, 123182
S. V. Ulianov
Institute of Gene Biology; Lomonosov Moscow State University
Email: shevelev@img.ras.ru
Russian Federation, Moscow, 119334; Moscow, 119192
