The Molten Globule Concept: 45 Years Later
- Authors: Bychkova V.E.1, Semisotnov G.V.1, Balobanov V.A.1, Finkelstein A.V.1
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Affiliations:
- Institute of Protein Research
- Issue: Vol 83, No 1 (2018): Suppl
- Pages: S33-S47
- Section: Review
- URL: https://journals.rcsi.science/0006-2979/article/view/151577
- DOI: https://doi.org/10.1134/S0006297918140043
- ID: 151577
Cite item
Abstract
In this review, we describe traditional systems where the molten globule (MG) state has been detected and give a brief description of the solution of Levinthal’s paradox. We discuss new results obtained for MG-mediated folding of “nontraditional” proteins and a possible functional role of the MG. We also report new data on the MG, especially the dry molten globule.
About the authors
V. E. Bychkova
Institute of Protein Research
Author for correspondence.
Email: uralm62@rambler.ru
Russian Federation, Pushchino, Moscow Region, 142290
G. V. Semisotnov
Institute of Protein Research
Email: uralm62@rambler.ru
Russian Federation, Pushchino, Moscow Region, 142290
V. A. Balobanov
Institute of Protein Research
Email: uralm62@rambler.ru
Russian Federation, Pushchino, Moscow Region, 142290
A. V. Finkelstein
Institute of Protein Research
Email: uralm62@rambler.ru
Russian Federation, Pushchino, Moscow Region, 142290