Adsorption of bacteriophages on bacterial cells
- Authors: Letarov A.V.1,2, Kulikov E.E.1,3
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Affiliations:
- Winogradskii Institute of Microbiology, Biotechnology Federal Research Center
- Faculty of Biology
- Department of Molecular and Biological Physics
- Issue: Vol 82, No 13 (2017)
- Pages: 1632-1658
- Section: Review
- URL: https://journals.rcsi.science/0006-2979/article/view/151552
- DOI: https://doi.org/10.1134/S0006297917130053
- ID: 151552
Cite item
Abstract
The biological functions of bacteriophage virions come down to the solution of three basic problems: to provide protection of viral nucleic acid from the factors of extracellular environment, to recognize a host suitable for phage replication, and to provide the delivery of nucleic acid through bacterial cell envelopes. This review considers the main regularities of phage–cell interaction at the initial stages of infection of tailed bacteriophages, from the reversible binding with receptors on the surface to the beginning of phage DNA entry. Data on the structure and functions of the phage adsorption apparatus, the main quantitative characteristics of the adsorption process, and the mechanisms of adaptation of phages and their hosts to each other effective at the stage of adsorption are presented.
About the authors
A. V. Letarov
Winogradskii Institute of Microbiology, Biotechnology Federal Research Center; Faculty of Biology
Author for correspondence.
Email: letarov@gmail.com
Russian Federation, Moscow, 117312; Moscow, 119991
E. E. Kulikov
Winogradskii Institute of Microbiology, Biotechnology Federal Research Center; Department of Molecular and Biological Physics
Email: letarov@gmail.com
Russian Federation, Moscow, 117312; Moscow, 141700
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