Bacterial therapy and mitochondrial therapy
- Authors: Popkov V.A.1, Plotnikov E.Y.1, Silachev D.N.1, Zorova L.D.1, Pevzner I.B.1, Jankauskas S.S.1, Zorov S.D.1, Andrianova N.V.1, Babenko V.A.1, Zorov D.B.1
-
Affiliations:
- Lomonosov Moscow State University
- Issue: Vol 82, No 12 (2017)
- Pages: 1549-1556
- Section: Review
- URL: https://journals.rcsi.science/0006-2979/article/view/151545
- DOI: https://doi.org/10.1134/S0006297917120148
- ID: 151545
Cite item
Abstract
Current methods for treatment of cellular and organ pathologies are extremely diverse and constantly evolving, going beyond the use of drugs, based on chemical interaction with biological targets to normalize the functions of the system. Because pharmacological approaches are often untenable, recent strategies in the therapy of different pathological conditions are of particular interest through introducing into the organism of some living system or its components, in particular, bacteria or isolated subcellular structures such as mitochondria. This review describes the most interesting and original examples of therapy using bacteria and mitochondria, which in perspective can dramatically change our views on the principles for the treatment of many diseases. Thus, we analyze such therapeutic effects from the perspective of the similarities between mitochondria and bacteria as the evolutionary ancestors of mitochondria.
Keywords
About the authors
V. A. Popkov
Lomonosov Moscow State University; Lomonosov Moscow State University
Email: zorov@genebee.msu.ru
Russian Federation, Moscow, 119991; Moscow, 119991
E. Y. Plotnikov
Lomonosov Moscow State University
Author for correspondence.
Email: plotnikov@genebee.msu.ru
Russian Federation, Moscow, 119991
D. N. Silachev
Lomonosov Moscow State University
Email: zorov@genebee.msu.ru
Russian Federation, Moscow, 119991
L. D. Zorova
Lomonosov Moscow State University
Email: zorov@genebee.msu.ru
Russian Federation, Moscow, 119991
I. B. Pevzner
Lomonosov Moscow State University
Email: zorov@genebee.msu.ru
Russian Federation, Moscow, 119991
S. S. Jankauskas
Lomonosov Moscow State University
Email: zorov@genebee.msu.ru
Russian Federation, Moscow, 119991
S. D. Zorov
Lomonosov Moscow State University
Email: zorov@genebee.msu.ru
Russian Federation, Moscow, 119991
N. V. Andrianova
Lomonosov Moscow State University
Email: zorov@genebee.msu.ru
Russian Federation, Moscow, 119991
V. A. Babenko
Lomonosov Moscow State University
Email: zorov@genebee.msu.ru
Russian Federation, Moscow, 119991
D. B. Zorov
Lomonosov Moscow State University
Author for correspondence.
Email: zorov@genebee.msu.ru
Russian Federation, Moscow, 119991