Email this article Molecular and cellular interactions between mother and fetus. Pregnancy as a rejuvenating factor
- Authors: Popkov V.A.1,2, Silachev D.N.1, Jankauskas S.S.1, Zorova L.D.3, Pevzner I.B.1, Babenko V.A.2,4, Plotnikov E.Y.1, Zorov D.B.1
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Affiliations:
- Lomonosov Moscow State University, Belozersky Institute of Physico-Chemical Biology
- Lomonosov Moscow State University, Faculty of Bioengineering and Bioinformatics
- Lomonosov Moscow State University, International Laser Center
- Research Center of Obstetrics, Gynecology and Perinatology
- Issue: Vol 81, No 12 (2016)
- Pages: 1480-1487
- Section: Phenoptosis (Special Issue)
- URL: https://journals.rcsi.science/0006-2979/article/view/151145
- DOI: https://doi.org/10.1134/S0006297916120099
- ID: 151145
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Abstract
Aging is associated with a decline of various body functions, including ability to regenerate. Over recent decades, it has been demonstrated that some of these changes could be reversed in response to factors originating from a young organism, for example, fetal stem cells or “young blood” in models of heterochronic parabiosis. Pregnancy might be considered as parabiotic model of the interaction between two organisms of different age. In this work, we analyzed and summarized data on the effects of pregnancy on the maternal organism that confirm the hypothesis that pregnancy rejuvenates the mother’s organism or slows its aging.
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About the authors
V. A. Popkov
Lomonosov Moscow State University, Belozersky Institute of Physico-Chemical Biology; Lomonosov Moscow State University, Faculty of Bioengineering and Bioinformatics
Email: zorov@genebee.msu.su
Russian Federation, Moscow, 119991; Moscow, 119991
D. N. Silachev
Lomonosov Moscow State University, Belozersky Institute of Physico-Chemical Biology
Email: zorov@genebee.msu.su
Russian Federation, Moscow, 119991
S. S. Jankauskas
Lomonosov Moscow State University, Belozersky Institute of Physico-Chemical Biology
Email: zorov@genebee.msu.su
Russian Federation, Moscow, 119991
L. D. Zorova
Lomonosov Moscow State University, International Laser Center
Email: zorov@genebee.msu.su
Russian Federation, Moscow, 119991
I. B. Pevzner
Lomonosov Moscow State University, Belozersky Institute of Physico-Chemical Biology
Email: zorov@genebee.msu.su
Russian Federation, Moscow, 119991
V. A. Babenko
Lomonosov Moscow State University, Faculty of Bioengineering and Bioinformatics; Research Center of Obstetrics, Gynecology and Perinatology
Email: zorov@genebee.msu.su
Russian Federation, Moscow, 119991; Moscow, 117997
E. Y. Plotnikov
Lomonosov Moscow State University, Belozersky Institute of Physico-Chemical Biology
Author for correspondence.
Email: plotnikov@genebee.msu.ru
Russian Federation, Moscow, 119991
D. B. Zorov
Lomonosov Moscow State University, Belozersky Institute of Physico-Chemical Biology
Author for correspondence.
Email: zorov@genebee.msu.su
Russian Federation, Moscow, 119991
