Mechanisms of changes in immune response during bacterial coinfections of the respiratory tract
- Authors: Sviriaeva E.N.1,2, Korneev K.V.1,2, Drutskaya M.S.1,2, Kuprash D.V.1,2
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Affiliations:
- Engelhardt Institute of Molecular Biology
- Faculty of Biology
- Issue: Vol 81, No 11 (2016)
- Pages: 1340-1349
- Section: Review
- URL: https://journals.rcsi.science/0006-2979/article/view/151097
- DOI: https://doi.org/10.1134/S0006297916110110
- ID: 151097
Cite item
Abstract
Acute diseases of the respiratory tract are often caused by viral pathogens and accompanying secondary bacterial infections. It is known that the development of such bacterial complications is caused mainly by a decreased infiltration with immune system cells and by suppressed inflammation in the lungs. There are significant advances in understanding the mechanisms of secondary infections, although many details remain unclear. This review summarizes current knowledge of the molecular and cellular changes in the host organism that can influence the course of bacterial coinfections in the respiratory tract.
About the authors
E. N. Sviriaeva
Engelhardt Institute of Molecular Biology; Faculty of Biology
Email: kuprash@gmail.com
Russian Federation, Moscow, 119991; Moscow, 119991
K. V. Korneev
Engelhardt Institute of Molecular Biology; Faculty of Biology
Email: kuprash@gmail.com
Russian Federation, Moscow, 119991; Moscow, 119991
M. S. Drutskaya
Engelhardt Institute of Molecular Biology; Faculty of Biology
Email: kuprash@gmail.com
Russian Federation, Moscow, 119991; Moscow, 119991
D. V. Kuprash
Engelhardt Institute of Molecular Biology; Faculty of Biology
Author for correspondence.
Email: kuprash@gmail.com
Russian Federation, Moscow, 119991; Moscow, 119991