Apoptosis in cryopreserved eukaryotic cells
- Authors: Savitskaya M.A.1, Onishchenko G.E.1
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Affiliations:
- Lomonosov Moscow State University
- Issue: Vol 81, No 5 (2016)
- Pages: 445-452
- Section: Reviews
- URL: https://journals.rcsi.science/0006-2979/article/view/150867
- DOI: https://doi.org/10.1134/S0006297916050023
- ID: 150867
Cite item
Abstract
This review considers apoptosis mechanisms that have been revealed in cryopreserved cells and which can be controlled using different chemical agents, thereby improving the viability of cells after their return to normal conditions. The role of oxidative stress as of the most significant damaging factor is discussed, as well as the reasonability of including antioxidants into cryopreservation/thawing protocols as independent agents or in combination with other compounds.
Keywords
About the authors
M. A. Savitskaya
Lomonosov Moscow State University
Author for correspondence.
Email: nakomis@mail.ru
Russian Federation, Moscow, 119991
G. E. Onishchenko
Lomonosov Moscow State University
Email: nakomis@mail.ru
Russian Federation, Moscow, 119991