Mathematical model of self-oscillations of activity of Kai proteins
- Authors: Bayramov S.K.1
-
Affiliations:
- Azerbaijan Medical University
- Issue: Vol 81, No 3 (2016)
- Pages: 284-288
- Section: Article
- URL: https://journals.rcsi.science/0006-2979/article/view/150813
- DOI: https://doi.org/10.1134/S0006297916030111
- ID: 150813
Cite item
Abstract
A non-autocatalytic mathematical model of self-oscillations in vitro in solutions of cyanobacterial Kai proteins (KaiA, KaiB, KaiC) and ATP is suggested. This model describes the process of phosphorylation/dephosphorylation of KaiC protein, which is accelerated by KaiA and inhibited by KaiB. The method of metabolic control analysis is used to show that frequency (period) as well as amplitude of self-oscillations of components of Kai proteins are temperature-compensated.
About the authors
Sh. K. Bayramov
Azerbaijan Medical University
Author for correspondence.
Email: shahinru@yahoo.com
Azerbaijan, Baku, AZ1022
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