Optimization of immunocorrection of collective immunity


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Abstract

Consideration was given to the possibility of applying the vector optimization methods and the optimal control theory to construction of the economy modes of maintaining the collective immunity to the infectious agent with allowance for the population psychology and medico-social effects of vaccination. Described was a population immunization model taking into account the natural immunization component. Cases of single and double vaccination with determination of their optimal modes were examined.

About the authors

I. D. Kolesin

St. Petersburg State University

Author for correspondence.
Email: kolesin_id@mail.ru
Russian Federation, St. Petersburg

E. M. Zhitkova

St. Petersburg State University

Email: kolesin_id@mail.ru
Russian Federation, St. Petersburg

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