Отправить статью по E-mail Antimicrobial Peptides in Health and Disease (Review)
- Авторы: Konovalova M.V.1, Zubareva A.A.2, Lutsenko G.V.1, Svirshchevskaya E.V.1
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Учреждения:
- Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
- Fundamentals of Biotechnology Institute of Bioengineering, Federal Research Center
- Выпуск: Том 54, № 3 (2018)
- Страницы: 238-244
- Раздел: Article
- URL: https://journals.rcsi.science/0003-6838/article/view/152469
- DOI: https://doi.org/10.1134/S0003683818030079
- ID: 152469
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Аннотация
The review describes the latest data on the role of antimicrobial peptides (AMPs) in health and disease, as well as their structure and mechanisms of action. AMPs mediate protection by both direct lysis of bacteria and also by regulation of inflammation and chemotaxis, thus demonstrating immunomodulatory properties. A large amount of data shows that AMPs play an important role in the pathogenesis of multiple chronic diseases with genetic predisposition, such as atopic dermatitis, rosacea, and scleroderma.
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Об авторах
M. Konovalova
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
Автор, ответственный за переписку.
Email: mariya.v.konovalova@gmail.com
Россия, Moscow, 117997
A. Zubareva
Fundamentals of Biotechnology Institute of Bioengineering, Federal Research Center
Email: mariya.v.konovalova@gmail.com
Россия, Moscow, 119071
G. Lutsenko
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
Email: mariya.v.konovalova@gmail.com
Россия, Moscow, 117997
E. Svirshchevskaya
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
Email: mariya.v.konovalova@gmail.com
Россия, Moscow, 117997
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