Antimutagenic systems based on chitosan conjugates with plant antioxidants
- 作者: Alexandrova V.A.1, Domnina N.S.2, Snigireva G.P.3
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隶属关系:
- Topchiev Institute of Petrochemical Synthesis
- Saint Petersburg State University
- Russian Scientific Center of Roentgen Radiology
- 期: 卷 52, 编号 5 (2016)
- 页面: 491-495
- 栏目: Article
- URL: https://journals.rcsi.science/0003-6838/article/view/152002
- DOI: https://doi.org/10.1134/S0003683816050033
- ID: 152002
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详细
It was shown using various methods that the radical scavenging and radical scavenging activities of chitosan conjugates with phenolic antioxidants of plant origin significantly exceed the corresponding values of their low molecular weight analogs (gallic and syringic acids, quercetin and dihydroquercetin). Cytogenetic analysis of human peripheral blood lymphocytes demonstrated that the conjugates showed pronounced antimutagenic efficiency when the cells were γ-irradiated in vitro at a dose of 2 Gy.
作者简介
V. Alexandrova
Topchiev Institute of Petrochemical Synthesis
编辑信件的主要联系方式.
Email: alexandrova@ips.ac.ru
俄罗斯联邦, Moscow, 119991
N. Domnina
Saint Petersburg State University
Email: alexandrova@ips.ac.ru
俄罗斯联邦, Saint Petersburg, 199034
G. Snigireva
Russian Scientific Center of Roentgen Radiology
Email: alexandrova@ips.ac.ru
俄罗斯联邦, Moscow, 117997
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