Antimutagenic systems based on chitosan conjugates with plant antioxidants
- Авторы: Alexandrova V.A.1, Domnina N.S.2, Snigireva G.P.3
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Учреждения:
- Topchiev Institute of Petrochemical Synthesis
- Saint Petersburg State University
- Russian Scientific Center of Roentgen Radiology
- Выпуск: Том 52, № 5 (2016)
- Страницы: 491-495
- Раздел: Article
- URL: https://journals.rcsi.science/0003-6838/article/view/152002
- DOI: https://doi.org/10.1134/S0003683816050033
- ID: 152002
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Аннотация
It was shown using various methods that the radical scavenging and radical scavenging activities of chitosan conjugates with phenolic antioxidants of plant origin significantly exceed the corresponding values of their low molecular weight analogs (gallic and syringic acids, quercetin and dihydroquercetin). Cytogenetic analysis of human peripheral blood lymphocytes demonstrated that the conjugates showed pronounced antimutagenic efficiency when the cells were γ-irradiated in vitro at a dose of 2 Gy.
Об авторах
V. Alexandrova
Topchiev Institute of Petrochemical Synthesis
Автор, ответственный за переписку.
Email: alexandrova@ips.ac.ru
Россия, Moscow, 119991
N. Domnina
Saint Petersburg State University
Email: alexandrova@ips.ac.ru
Россия, Saint Petersburg, 199034
G. Snigireva
Russian Scientific Center of Roentgen Radiology
Email: alexandrova@ips.ac.ru
Россия, Moscow, 117997
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