Bacterial cellulose synthesized by Gluconacetobacter hansenii for medical applications
- Authors: Gromovykh T.I.1, Sadykova V.S.2, Lutcenko S.V.1, Dmitrenok A.S.3, Feldman N.B.1, Danilchuk T.N.4, Kashirin V.V.1
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Affiliations:
- I.M. Sechenov First Moscow State Medical University
- G.F. Gauze Scientific-Research Institute of New Antibiotics
- N.D. Zelinsky Institute of Organic Chemistry
- Moscow State University of Food Production
- Issue: Vol 53, No 1 (2017)
- Pages: 60-67
- Section: Article
- URL: https://journals.rcsi.science/0003-6838/article/view/152152
- DOI: https://doi.org/10.1134/S0003683817010094
- ID: 152152
Cite item
Abstract
The properties of a polymer synthesized by the Gluconacetobacter hansenii strain GH-1/2008 were investigated. The studied bacterial cellulose polymer films are characterized by a mesh nanostructure composed of micro- and macrofibrils, a high water absorption capacity 556 ± 16.8%, and high strength and elasticity. Analysis of the spectrum recorded by 13С CP/MAS NMR spectroscopy showed that the bacterial cellulose synthesized by G. hansenii GH-1/2008 is a pure compound composed of Iα (65–70%) and Iβ (30–35%) allomorphs without any other impurities. It was found that the bacterial cellulose films with adsorbed antibiotics such as amoxiclav and fluconazole can be used as antibacterial and antifungal wound healing materials.
About the authors
T. I. Gromovykh
I.M. Sechenov First Moscow State Medical University
Author for correspondence.
Email: gromovykhtatyana@mail.ru
Russian Federation, Moscow, 119991
V. S. Sadykova
G.F. Gauze Scientific-Research Institute of New Antibiotics
Email: gromovykhtatyana@mail.ru
Russian Federation, Moscow, 119119021991
S. V. Lutcenko
I.M. Sechenov First Moscow State Medical University
Email: gromovykhtatyana@mail.ru
Russian Federation, Moscow, 119991
A. S. Dmitrenok
N.D. Zelinsky Institute of Organic Chemistry
Email: gromovykhtatyana@mail.ru
Russian Federation, Moscow, 119991
N. B. Feldman
I.M. Sechenov First Moscow State Medical University
Email: gromovykhtatyana@mail.ru
Russian Federation, Moscow, 119991
T. N. Danilchuk
Moscow State University of Food Production
Email: gromovykhtatyana@mail.ru
Russian Federation, Moscow, 125080
V. V. Kashirin
I.M. Sechenov First Moscow State Medical University
Email: gromovykhtatyana@mail.ru
Russian Federation, Moscow, 119991
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