Sodium Alginate Based Mucoadhesive Hydrogels

M. Yu. Gorshkova; I. F. Volkova; L. V. Vanchugova; I. L. Valuev; L. I. Valuev

doi:10.1134/S0003683819040045

Sodium Alginate Based Mucoadhesive Hydrogels

Authors: Gorshkova M.Y.¹, Volkova I.F.¹, Vanchugova L.V.¹, Valuev I.L.¹, Valuev L.I.¹
Affiliations:
1. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences
Issue: Vol 55, No 4 (2019)
Pages: 371-374
Section: Article
URL: https://journals.rcsi.science/0003-6838/article/view/152923
DOI: https://doi.org/10.1134/S0003683819040045
ID: 152923

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Abstract

The potential use of sodium-alginate hydrogels as mucoadhesive drug delivery carriers for intranasal application is studied. It is demonstrated that the drug release rate is dependent on the drug solubility in water, the drug concentration in the carrier, and the degree of alginate crosslinking.