Antimicrobial Activity of Silver Nanoparticles in a Carboxymethyl Chitin Matrix Obtained by the Microwave Hydrothermal Method


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Abstract

Silver nanoparticles have been obtained in a matrix of 6-O-carboxymethyl chitin in the presence of D-glucose as a reducing agent by microwave hydrothermal synthesis. The TEM results show that the silver nanoparticles have a spherical shape; the particle size range is 3–20 nm. The resulting colloidal solution of silver nanoparticles had a strong bacterial effect on gram-positive bacteria Staphylococcus aureus ATCC 21027 (=209 P), Bacillus subtilis ATCC 6633, and, to a lesser extent, on gram-negative bacteria Escherichia coli АТСС 25922. The synthesized silver nanoparticles showed pronounced fungistatic activity against A. niger INA 00760.

About the authors

V. A. Alexandrova

A.V. Topchiev Institute of Petrochemical Synthesis

Author for correspondence.
Email: alexandrova@ips.ac.ru
Russian Federation, Moscow, 119991

L. N. Shirokova

A.V. Topchiev Institute of Petrochemical Synthesis

Email: alexandrova@ips.ac.ru
Russian Federation, Moscow, 119991

V. S. Sadykova

G.F. Gause Institute of New Antibiotics

Email: alexandrova@ips.ac.ru
Russian Federation, Moscow, 119021

A. E. Baranchikov

N.S. Kurnakov Institute of General and Inorganic Chemistry

Email: alexandrova@ips.ac.ru
Russian Federation, Moscow, 119991

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