Effect of Gelling Additives on the Behavior of Bioactive TiO2–P2O5/ZnO Composites in a Model Solution

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Abstract

Bioactive TiO2–P2O5/ZnO composites were obtained, which are modified zinc oxide granules (in the inner part) based on Tokem 250 cationite, coated with a titanate-phosphate gel based on the TiO2–P2O5 system, followed by immersion in a solution of polyvinyl alcohol (PVA) or hydrolyzed liquid glass (sodium silicate). The heat treatment mode of the material is set: stepwise annealing for 30 minutes (150, 250, 350°C), 6 hours (600°C), 1 hour (800°C). The ability to form a calcium phosphate layer on the surface due to the presence of active Ti4+ surface centers was confirmed by trilometric titration to determine the total concentration of calcium and magnesium ions in SBF solution. After immersion in an SBF solution, micro-X-ray spectral analysis captures calcium, zinc, oxygen, titanium, and phosphorus on the surface of the composites, which corresponds to the physiological composition characteristic of bone tissue. To shape the biomaterial, PVA and liquid glass were introduced as gelling additives. The introduction of gelling additives has a beneficial effect on the biological properties of composites, but the stabilization of the total concentration of Ca2+ and Mg2+ ions in samples with a gelling additive of PVA occurs faster than with liquid glass. The obtained samples can be recommended for further research.

About the authors

E. S Lyutova

National Research Tomsk State University

Email: lyutova.tsu@mail.ru
Tomsk, Rassian Federation

F. I Sharipova

National Research Tomsk State University

Tomsk, Rassian Federation

Yu. S Gruzdeva

National Research Tomsk State University

Tomsk, Rassian Federation

D. K Ivanova

National Research Tomsk State University

Tomsk, Rassian Federation

L. P Borilo

National Research Tomsk State University

Tomsk, Rassian Federation

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