НIGH-RENIN HYPERTENSIONS: FROM SYMPTOM TO dIAGNOSIS

封面

如何引用文章

全文:

详细

The article highlights the current understanding of renin-angiotensin-aldosterone system function- ing, as well as mechanisms for blood pressure raising depending on its activity. Authors presented data on the prevalence and characteristics of arterial hypertension with high levels of renin. Along with high-renin essential hypertension authors considered secondary arterial hypertensions accompanied by high-renin status increasing the diagnostic value of this hormone determination and explains the fea- tures of pathophysiological processes occurring in patients’ organism. Authors proved the importance of renin status diagnostic studies allowing defining a successful strategy of antihypertensive therapy.

作者简介

A Barsukov

Military Medical Academy named after S.M. Kirov

N Korneychuk

Military Medical Academy named after S.M. Kirov

S Shustov

Military Medical Academy named after S.M. Kirov

参考

  1. Atlas S.A. The reninangiotensin aldosterone system: pathophysiological role and pharmacologic inhibition / S.A. Atlas // J Manag Care Pharm. - 2007. - Vol. 13, № 8 Suppl B. - Р. 920.
  2. Phillips M.I. The discovery of renin 100 years ago / M.I. Phillips, K.M. Schmidt Ott // News Physiol. Sci. - 1999. - Vol. 14. - P. 271274.
  3. Goldblatt H. Studies on experimental hypertension: the production of persistent elevation of systolic blood pressure by means of renal ischemia / H. Goldblatt, J. Lynch, R.F. Hanzel et al. // J. Exp. Med. - 1934. - Vol. 59. - P. 347379.
  4. Piepho R.W. An overview of antihypertensive therapy in the 20th century / R.W. Piepho, J. Beal // J Clin Pharmacol. - 2000. - Vol. 40. - P. 967977.
  5. Ferrario C.M. AngiotensinConverting Enzyme 2 and Angiotensin(17): An Evolving Story in Cardiovascular Regulation / C.M. Ferrario // Hypertension. - 2006. - Vol. 47. - P. 515521.
  6. Skeggs L.T Jr. The preparation and function of the hypertensionconverting enzyme / L.T Jr Skeggs, J.R Kahn, N.P. Shumway // J. Exp. Med. - 1956. - Vol. 103. - P. 295299.
  7. Sealey J.E. The reninangiotensinaldosterone system for normal regulation of blood pressure and sodium and potassium homeostasis/ J.E Sealey, J.H Laragh In: Laragh JH, Brenner BM, eds. Hypertension: Pathophysiology, Diagnosis and Management. 2 ed. New York: Raven Press. - 1995. - P. 17631795.
  8. Danser A.H. Renin, prorenin and the putative (pro) renin receptor/ A.H. Danser, J. Deinum // Hypertension. - 2005. - Vol. 46, № 5. - P. 10691076.
  9. Максимов М.Л. Лабораторная диагностика активности ренинангиотензинальдостероновой системы / М.Л. Максимов, О.В. Дралова, В.Л. Купрейчик и соавт. // Креативная кардиология. - 2010. - № 1. - C. 5461.
  10. Brown M.J. Renin: friend or foe / M.J. Brown // Heart. - 2007. - Vol. 93. - P. 10261033.
  11. Morgan L. Angiotensinogen: molecular biology, biochemistry and physiology / L. Morgan, F.B. Pipkin, N. Kalsheker // Int. J. Biochem. Cell. Biol. - 1996. - Vol. 28. - P. 12111222
  12. Urata H. Identification of high specific chymase as a major angiotensin IIforming enzyme in the human heart/ H. Urata, A. Kinoshita, K.S. Misono et al. // J. Biol. Chem. - 1990. - Vol. 265. - P. 2234822357.
  13. Ihara M. Increased chymasedependent angiotensin II formation in human atherosclerotic aorta/ M. Ihara, H. Urata, A. Kinoshita et al. // Hypertension. - 1999. - Vol. 33, № 6. - P. 13991405.
  14. Kurtz A. Regulation of renin secretion by angiotensin IIAT1 receptors / A. Kurtz, C. Wagner // J Am Soc Nephrol. - 1999. - Vol. 10, Suppl. 11. - P. 162168.
  15. Azizi M. Integrating drug pharmacokinetics for phenotyping individual renin response to angiotensin II blockade in humans / M. Azizi, A. Bissery, M. LamarieCliche et al. // Hypertension. - 2004. - Vol. 43. - P. 785790.
  16. Paul M. Physiology of local reninangiotensin systems / M. Paul, A.P. Mehr, R. Kreutz // Physiol. Rev. - 2006. - Vol. 86, № 3. - P. 747803.
  17. Santos R.A. Angiotensin (17) and the reninangiotensin system / R.A. Santos, A.J. Ferreira // Curr. Opin. Nephrol. Hypertens. - 2007. - Vol. 16. - P. 122128.
  18. Nguyen G. Prorenin and (pro)renin receptor, a review of available data from in vitro studies and experimental models in rodents / G. Nguyen, A.H. Danser // Exp. Physiol. - 2009. - Vol. 93. - P. 557563.
  19. van Kats J.P. Adrenal angiotensin. Origin and site of generation / J.P. van Kats, W. Chai, D.J. Duncker et al. // Am. J. Hypertens. - 2005. - Vol. 18. - P. 10451051.
  20. Laragh J.H. The Plasma Renin Test Reveals the Contribution of Body SodiumVolume Content (V) and ReninAngiotensin (R) Vasoconstriction to LongTerm Blood Pressure / J.H. Laragh, J.E. Sealey // Am. J. Hypertens. - 2011. - Vol. 24, № 11. - P. 11641180.
  21. Laragh J. Vasoconstrictionvolume analysis for understanding and treating hypertension: the use of renin and aldosterone profiles / J. Laragh // Am. J. Med. - 1973. - Vol. 55. - P. 261.
  22. Laragh J. Laragh’s lessons in pathophysiology and clinical pearls for treating hypertension / J. Laragh // Am J Hypertens. - 2001. - Vol. 14. - P. 733742.
  23. Funder J.W. Case detection, diagnosis, and treatment of patients with primary aldosteronism: an endocrine society clinical practice guideline / J.W. Funder, R.M. Carey, C. Fardella et al. // J. Clin. Endocrinol. Metab. - 2008. - Vol. 93, № 9. - P. 32663281.
  24. Laragh J.H. The plasma renin test reveals the contribution of body sodiumvolume content and reninangiotensin vasoconstriction to long term blood pressure / J.H. Laragh, J.E. Sealey // Am. J. Hypertens. - 2011. - Vol. 24. - P. 11641180.
  25. Alderman M.H. Association of the reninsodium profile with the risk of myocardial infarction in patients with hypertension / M.H. Alderman, Shanta Madhavan, L.Wee Ooi et al. // The new England J. of medicine. - 1991. - P. 10981104.
  26. Brown Morris J. Clinical Value of Plasma Renin Estimation in the Management of Hypertension / J. Brown Morris //Am. J. Hypertens. - 2014. - Vol. 27, № 8. - P. 10131016.
  27. Барсуков А.В. К вопросу об особенностях ренинового статуса в популяции пациентов с артериальной гипертензией / А.В. Барсуков, Н.Н. Корнейчук, М.Ю. Нижегородцев // Мат. Всероссийской научнопрактической конференции, посвященной 175летию кафедры госпитальной терапии и 1 кафедры (терапии усовершенствования врачей) Военномедицинской академии имени С.М. Кирова “Избранные вопросы внутренней медицины”. - СПб: ВМедА, 2016. - С. 16.
  28. de Leeuw P.W. Vasoregulation and renal function / P.W. de Leeuw // Ijrukkerij EnedNeede. - 1978. - 21 p.
  29. de Boer R.A. Plasma renin and outcome in the community: Data from prevend / R.A. de Boer, N.F. Schroten, S.J. Bakker et al. // Eur. Heart J. - 2012. - Vol. 33. - P. 23512359.
  30. Гончаров Н.П. Оценка информативности определения активности ренина плазмы и прямого ренина при диагностике первичного альдостеронизма / Н.П. Гончаров, Г.С. Колесникова, Г.В. Кация и соавт. // Проблемы эндокринологии. - 2012. - № 5. - С. 2127.
  31. Koga M. Plasma renin activity could be a useful predictor of left ventricular hypertrophy in essential hypertensives / M. Koga, M. Sasaguri, S. Miura et al. // Journal of human hypertension. - 1998. - Vol. 12, № 7. - P. 455461.
  32. Барсуков А.В. Особенности структурнофункционального ремоделирования сердца и нейрогуморальной регуляции кровообращения у пациентов с эссенциальной артериальной гипертензией, имеющих асимметричную гипертрофию левого желудочка / А.В. Барсуков, Е.В. Пронина, М.В. Резванцев // Вестник Российской Военномедицинской академии. - 2007. - № 2. - С. 1417.
  33. Глуховской Д.В. Особенности состояния ренинангиотензинальдостероновой системы и инсулинорезистентности у пациентов с артериальной гипертензией в зависимости от геометрических особенностей левого предсердия / Д.В. Глуховской, А.В. Барсуков, А.В. Гордиенко и соавт. // Врачаспирант. - 2012. - № 4.1 (53). - С. 123132.
  34. Sever P.S. Is plasma renin activity a biomarker for the prediction of renal and cardiovascular outcomes in treated hypertensive patients? Observations from the AngloScandinavian Cardiac Outcomes Trial (ASCOT) / P.S. Sever, C.L. Chang, M.F. Prescott et al. // Eur. Heart J. - 2012. - Vol. 33, № 23. - P. 29702979.
  35. Alderman M. Urinary sodium excretion and myocardial infarction in hypertensive patients: a prospective cohort study / M. Alderman, J. Sealey, H. Cohen et al. //Am. J. Clin. Nutr. - 1997. - Vol. 65 (2 Suppl). - P. 682686.
  36. Verma S. Plasma renin activity is associated with increased cardiovascular events and mortality in the HOPE Study / S. Verma, M. Gupta, D.T. Holmes et al. // Circulation. - 2009. - Vol. 120. - P. 453.
  37. Gonzalez M.C. Enduring direct association of baseline plasma renin activity with allcause and cardiovascular mortality in hypertensive patients / M.C. Gonzalez, H.W. Cohen, J.E. Sealey et al. // Am. J. Hypertens. - 2011. - Vol. 24, № 11. - P. 11811186.
  38. Volpe M. Plasma renin and cardiovascular risk: what is the evidence for an association? / M. Volpe, T. Unger // Cardiology. - 2013. - Vol. 125, № 1. - P. 5059.
  39. Laragh J.H. Abstract, closing summary, and table of contents for Laragh's 25 lessons in pathophysiology and 12 clinical pearls for treating hypertension / J.H. Laragh // Am. J. Hypertens. - 2001. - Vol. 14, № 12. - P. 11731177.
  40. Buhler F.R. Renin profiling to select antihypertensive baseline drugs. Renin inhibitors for highrenin and calcium entry blockers for lowrenin patients / F.R. Buhler, P. Bolli, W. Kiowski et al. // Am. J. Med. - 1984. - Vol. 77. - P. 3642.
  41. Stoicescu M. The role of increased plasmatic renin level in the pathogenesis of arterial hypertension in young adults / M. Stoicescu, C. Csepento, G. Muţiu et al. // Rom. J. Morphol. Embryol. - 2011. - Vol. 52, 1 Suppl. - P. 419423.
  42. Safian R.D. Renal artery stenosis / R.D. Safian, S.C. Textor // N. Engl. J. Med. - 2001. - Vol. 344. - P. 431442.
  43. Ram C.V. Renovascular hypertension / C.V. Ram // Curr. Opin. Nephrol. Hypertens. - 1997. - Vol. 6. - P. 575579.
  44. Чазова И.Е. Диагностика и лечение артериальной гипертензии (Рекомендации Российского медицинского общества по артериальной гипертонии и Всероссийского научного общества кардиологов) / И.Е. Чазова, Л.Г. Ратова, С.А. Бойцов и соавт. // Системные гипертензии. - 2010. - № 3. - С. 526.
  45. Hansen K.J. Prevalence of renovascular disease in eldery: a population based study / K.J. Hansen, M.S. Edwards et al. // J. Vasc. Surg. - 2002. - Vol. 36. - P. 443451.
  46. Crowley J.J. Progression of renal artery stenosis in patients undergoing cardiac catheterization / J.J. Crowley, R.M. Santos, R.H. Peter et al. // Am. Heart J. - 1998. - Vol. 136. - P. 913918.
  47. Caps M.T. Prospective study of atherosclerotic disease progression in the renal artery / M.T. Caps, C. Perissinotto, R.E. Zierler et al. // Circulation. - 1998. - Vol. 98. - P. 28662872.
  48. Rundback J.H. Guidelines for the reporting of renal artery revascularization in clinical trials. American Heart Association / J.H. Rundback, D. Sacks, K.C. Kent et al. // Circulation. - 2002. - Vol. 106. - P. 15721585.
  49. Soares G.M. Renal artery duplex ultrasonography as a screening and surveillance tool to detect renal artery stenosis: a comparison with current reference standard imaging / G.M. Soares, T.P. Murphy, M.S. Singha et al. // J. Ultrasound Med. - 2006. - Vol. 25. - P. 293298.
  50. Mancia G. 2013 ESH/ESC Guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC) / G. Mancia, R. Fagard, K. Narkiewicz et al. // J. of Hypertension. - 2013. - Vol. 31, № 7. - P. 12811357.
  51. Robertson P.W. Hypertension due to a reninsecreting renal tumour / P.W. Robertson, A. Klidjian, L.K. Harding et al. // Am J Med. - 1967. - Vol. 43, № 6. - P. 963976.
  52. Kuroda N. Juxtaglomerular cell tumor: a morphological, immunohistochemical and genetic study of six cases / N. Kuroda, S. Maris, F.A. Monzon et al. // Hum. Pathol. - 2013. - Vol. 44, № 1. - P. 4754.
  53. Garel L. Reninoma of the left kidney / L. Garel, P. Robitaille, J. Dubois et al. // Radiographics. - 1993. - Vol. 13, № 2. - P. 477479.
  54. Shao L. Juxtaglomerular cell tumor in an 8yearold girl / L. Shao, M. Manalang, L. Cooley // Pediatr. Blood Cancer. - 2008. - Vol. 50, № 2. - P. 406409.
  55. Méndez G.P. Juxtaglomerular cell tumor of the kidney: case report and differential diagnosis with emphasis on pathologic and cytopathologic features / G.P. Méndez, C. Klock, V. Nosé // Int. J. Surg. Pathol. - 2011. - Vol. 19, № 1 - P. 9398.
  56. Mao J. Recurrent hypertensive cerebral hemorrhages in a boy caused by a reninoma: rare manifestations and distinctive electron microscopy findings / J. Mao, Z. Wang, X. Wu et al. // J. Clin. Hypertens. (Greenwich). - 2012. - Vol. 14, № 11. - P. 802805.
  57. Duan X. Metastatic juxtaglomerular cell tumor in a 52yearold man / X. Duan, P. Bruneval, R. Hammadeh et al. // Am. J. Surg. Pathol. - 2004. - Vol. 28, № 8. - P. 10981102.
  58. Altaf H. Shera. Recurrent malignant juxtaglomerular cell tumor: A rare cause of malignant hypertension in a child / H. Altaf Shera, A. Aejaz Baba, H. Iftikhar Bakshi et al. // J. Indian Assoc. Pediatr. Surg. - 2011. - Vol. 16, № 4. - P. 152154.
  59. Gennari F.J. Pathophysiology of metabolic alkalosis: a new classification based on the centrality of stimulated collecting duct ion transport / F.J. Gennari // Am. J. Kidney Dis. - 2011. - Vol. 58, № 4. - P. 626636.
  60. Wong L. Reninoma: case report and literature review / L. Wong, T.H. Hsu, M.G. Perlroth et al. // J. Hypertens. - 2008. - Vol. 26, № 2. - P. 368373.
  61. Haab F. Reninsecreting tumors: Diagnosis, conservative surgical approach and longterm results / F. Haab, J.M. Duclos, T. Guyenne et al. // J. Urol. - 1995. - Vol. 153. - P. 17811784.
  62. McVicar M. Hypertension secondary to reninsecreting juxtaglomerular cell tumor: Case report and review of 38 cases / M. McVicar, C. Carman, M. Chandra et al. // Pediatr. Nephrol. - 1993. - Vol. 7. - P. 404412.
  63. Hanna W. Juxtaglomerular cell tumour (reninoma) with paroxysmal hypertension / W. Hanna, B. Tepperman, AG. Logan et al. // CMAJ. - 1979. - Vol. 120. - P. 957959.
  64. Wolley M. Reninoma: the importance of renal vein renin ratios for lateralisation and diagnosis / M. Wolley, R.D. Gordon, M. Stowasser // Am J Nephrol. - 2014. - Vol. 39, № 1. - P. 1619.
  65. Osawa S. Juxtaglomerular cell tumor that was preoperatively diagnosed using selective renal venous sampling / S. Osawa, Y. Hosokawa, T. Soda et al. // Intern Med. - 2013. - Vol. 52, № 17. - P. 19371942.
  66. Rajagopalan S. Complete reninangiotensinaldosterone system (RAAS) blockade in highrisk patients: recent insights from renin blockade studies / S. Rajagopalan, G.L. Bakris, W.T. Abraham et al. // Hypertension. - 2013. - Vol. 63, № 3. - P. 444910.
  67. Martin S.A. Juxtaglomerular cell tumor: a clinicopathologic study of four cases and review of the literature / S.A. Martin, L.A. Mynderse, D.J. Lager et al. // Am. J. Clin. Pathol. - 2001. - Vol. 116, № 6. - P. 854863.
  68. Rubenstein J.N. Juxtaglomerular apparatus tumour: A rare surgically correctable cause of hypertension / J.N. Rubenstein, S.E. Eggener, M.R. Pins et al. // Rev. Urol. - 2002. - Vol. 4. - P. 192195.
  69. DeLellis R.A. World Health Organization (2004) WHO Classification of Tumours, Pathology and genetics of tumours of endocrine organs / R.A. DeLellis, R.V. Lloyd, P.U. Heitz et al. // Lyon: IARC Press. - 2004.
  70. Jacques W.M. Lenders. Pheochromocytoma and Paraganglioma: An Endocrine Society Clinical Practice Guideline / W.M. Jacques Lenders, Duh QuanYang, Graeme Eisenhofer et al. // J. Clin. Endocrinol. Metab. - 2014. - Vol. 99, № 6. - P. 19151942.
  71. Pacak K. Pheochromocytoma: recommendations for clinical practice from the First International Symposium. October 2005 / K. Pacak, G. Eisenhofer, H. Ahlman et al. // Nat. Clin. Prac. Endocrinol. Metab. - 2007. - Vol. 3. - P. 92102.
  72. Славнов В.Н. Ренинангиотензинальдостероновая система у пациентов с гипертонической болезнью и эндокринными гипертензиями / В.Н. Славнов, С.Ю. Савицкий, Н.П. Строганова // Укр. Кардиол. Журн. - 2013, № 4. - С. 111116.
  73. Ветшев П.С. Феохромоцитома: клиника, диагностика, хирургическое лечение / П.С. Ветшев, В.Б. Симоненко, Л.И. Ипполитов и соавт. // Aнн. хир. гепатол. - 2003. - № 8 (2). - C. 4855.
  74. KirkbyBott J. Ectopic hormonesecreting pheochromocytoma: a francophone observational study / J. KirkbyBott, L. Brunaud, M. Mathonet et al. // World J Surg. - 2012. - Vol. 36, № 6. - P. 13821388.
  75. Пальцев М.А. Патологическая анатомия: национальное руководство / М.А. Пальцев, Л.В. Кактурский, О.В. Зайратьянц // М.: ГЭОТАР - Медиа. - 2011. - C. 1264.

版权所有 © Barsukov A.V., Korneychuk N.N., Shustov S.B., 2017

Creative Commons License
此作品已接受知识共享署名 4.0国际许可协议的许可

##common.cookie##