Chronic atrophic gastritis: focus on diagnosis
- Authors: Bakulin I.G.1, Sushilova A.G.1, Zharkov A.V.1,2
-
Affiliations:
- North-Western State Medical University named after I.I. Mechnikov
- Healthcare Committee of the Leningrad Region
- Issue: Vol 15, No 3 (2023)
- Pages: 13-24
- Section: Reviews
- URL: https://journals.rcsi.science/vszgmu/article/view/249453
- DOI: https://doi.org/10.17816/mechnikov623654
- ID: 249453
Cite item
Abstract
Currently, chronic atrophic gastritis is a risk factor for the development of gastric cancer. Data on the prevalence of chronic atrophic gastritis in Russia and the world are limited. Among the adult population of St. Petersburg aged 21 to 81 years, the prevalence of histologically verified chronic atrophic gastritis is 5.3%. Moreover, the chances of developing chronic atrophic gastritis in people over the age of 60 years compared to the group of 45–59 years are 2.5 times higher (95% confidence interval 1.5–4.1).
Morphological verification of the Operative Link for Gastritis Assessment diagnosis is not carried out in clinical practice in most cases. However, this method remains the most reliable method for timely verification of chronic atrophic gastritis, including chronic atrophic gastritis of mixed origin (autoimmune gastritis and Helicobacter pylori-associated gastritis), especially in the case of a seronegative variant of autoimmune gastritis.
Also, in addition to the heterogeneity of epidemiological data on chronic atrophic gastritis, there is disagreement about how to confirm its etiology as well as about the correlation of serological markers of atrophy and histological stage.
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##article.viewOnOriginalSite##About the authors
Igor G. Bakulin
North-Western State Medical University named after I.I. Mechnikov
Email: igbakulin@yandex.ru
ORCID iD: 0000-0002-6151-2021
SPIN-code: 5283-2032
MD, Dr. Sci. (Med.), Professor
Russian Federation, Saint PetersburgAnastasiia G. Sushilova
North-Western State Medical University named after I.I. Mechnikov
Author for correspondence.
Email: anastasiya.s1311@gmail.com
ORCID iD: 0000-0002-7277-5046
SPIN-code: 4026-5160
MD, postgraduate student
Russian Federation, Saint PetersburgAlexander V. Zharkov
North-Western State Medical University named after I.I. Mechnikov; Healthcare Committee of the Leningrad Region
Email: al.zharkov@bk.ru
ORCID iD: 0000-0001-6649-0928
MD, Cand. Sci. (Med.)
Russian Federation, Saint Petersburg; Saint PetersburgReferences
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