Varicocele as a manifestation of connective tissue dysplasia

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Varicocele is spread in 35% of men with primary infertility and in 70-81% of men with secondary infertility, being common in 15% of the entire male population. The prevalence and recurrence of varicocele are relevant for investigating of the underlying etiological mechanisms of this disease.

Objective: to evaluate the prevalence of connective tissue dysplasia in patients with varicocele.

Materials and methods. A clinical study is conducted in 148 patients with varicocele. A generally accepted minor congenital anatomical abnormalities were discovered during the examination. Electrocardiography, intervalography and echocardiography were provided among all patients.

Results. 129 people (87.2%) of the examined patients with varicocele had connective tissue dysplasia. The most frequent manifestations of connective tissue dysplasia are: malformation of ear pavilion (90.5%), asthenic body type (79.2%), disturbed occlusion and tooth growth (52.7%), arterial hypotension (47.3%). In the vast majority of cases (104 people, 70.2%) electrocardiograms of 148 patients with varicocele demonstrated different types of arrhythmia. In intervalography it was found that in half of the cases (83 patients, 56.1%) patients had disorders of the autonomic nervous system. During the regular echocardiography only 32 people (21.6%) didn’t have any heart disease, on the other hand valvular and myocardial lesions were diagnosed in other patients.

Conclusions. The deficiency of mesenchymal structures within the connective tissue dysplasia in varicocele is a systemic predisposing factor and requires a more in-depth examination of the cardiovascular system in such patients.

作者简介

Anton Tsukanov

Omsk State Medical University

编辑信件的主要联系方式.
Email: tsoukanov2000@mail.ru

Doctor of Medical Science, Professor, Head of Department of Surgical Diseases and Urology

俄罗斯联邦, Omsk

Sofija Semikina

Omsk State Medical University

Email: tsoukanov2000@mail.ru

student

俄罗斯联邦, Omsk

Ruslan Mustafayev

Surgut City Clinical Polyclinic No. 2

Email: tsoukanov2000@mail.ru

urologist

俄罗斯联邦, Surgut

参考

  1. Бердников М.А., Антипов Н.В. Варикоцеле: современная проблема // Журнал фундаментальной медицины и биологии. – 2016. – № 3. – С. 42–50. [Berdnikov MA, Antipov NV. Varicocele: the modern problem. Zhurnal fundamental’noj mediciny i biologii. 2016;(3):42-50. (In Russ.)]
  2. Капто А.А. Артериовенозные конфликты у мужчин с урологической патологией // Урологические ведомости. – 2018. – Т. 8. – № 2. – С. 53–63. [Kapto AA. Arteryovenous conflicts in men with urological pathology. Urologicheskie vedomosti. 2018;8(2):53-63. (In Russ.)]. https://doi.org/10.17816/uroved8253-63.
  3. Капто А.А., Виноградов И.В. К патогенезу рецидивного варикоцеле // Урологические ведомости. – 2017. – Т. 7. – № S. – С. 46–47. [Kapto AA, Vinogradov IV. K patogenezu recidivnogo varikocele. Urologicheskie vedomosti. 2017;7(S):46-47. (In Russ.)]
  4. Капто А.А., Жуков О.Б. Варикозная болезнь малого таза у мужчин (обзор литературы) // Андрология и генитальная хирургия. – 2016. – № 2. – С. 10–19. [Kapto AA, Zhukov OB. Varicose veins in the male small pelvis (a review of literature). Andrology and genital surgery journal. 2016;(2):10-19. (In Russ.)]. https://doi.org/10.17650/2070-9781-2016-17-2-10-19.
  5. Leppig KA, Werler MM, Cann EJ, et al. Predictive value of minor anomalies. I. Association with major malformations. J Pediatr. 1987;110(4):531-537. https://doi.org/10.1016/s0022-3476(87) 80543-7.
  6. Тябут Т.Д., Каратыш О.М. Недифференцированная дисплазия соединительной ткани // Современная ревматология. – 2009. – Т. 3. – № 2. – С. 19–23. [Tyabut TD, Karatysh OM. Nedifferencirovannaya displaziya soedinitel’noj tkani. Sovremennaya revmatologiya. 2009;3(2):19-23. (In Russ.)]
  7. Цуканов Ю.Т., Цуканов А.Ю., Щеглов А.Ю., Мозговой С.И. Патоморфологические аспекты варикозного поражения вен нижней половины туловища // Вестник Санкт-Петербургского университета. – Серия «Медицина». – 2006. – № 3. – С. 50–61. [Tsukanov YuT, Tsukanov AYu, Sheglov AYu, Mozgovoi SI. Morphological aspects of varicose lesions of lower half of the body. Vestnik Sankt-Peterburgskogo universiteta. Medicina. 2006;(3):50-61. (In Russ.)]
  8. Цуканов Ю.Т., Цуканов А.Ю. Дисплазия соединительной ткани как морфофункциональная основа формирования флебопатии и варикозной болезни // Регионарное кровообращение и микроциркуляция. – 2002. – № 3. – С. 44–47. [Tsukanov YuT, Tsukanov AYu. Displasia of connective tissue as a morphofunctional basis of formation phlebopaty and varicose disease. Regionarnoe krovoobrashchenie i mikrocirkulyaciya. 2002;(3):44-47. (In Russ.)]
  9. Нечаева Г.И., Яковлев В.М., Конев В.П., и др. Дисплазия соединительной ткани: основные клинические синдромы, формулировка диагноза, лечение // Лечащий врач. – 2008. – № 2. – С. 22–28. [Nechaeva GI, Yakovlev VM, Konev VP, et al. Displaziya soedinitel’noj tkani: osnovnye klinicheskie sindromy, formulirovka diagnoza, lechenie. Practitioner. 2008;(2):22-28. (In Russ.)]
  10. Нечаева Г.И., Викторова И.А., Друк И.В. Дисплазия соединительной ткани: распространенность, фенотипические признаки, ассоциации с другими заболеваниями // Врач. – 2006. – № 1. – С. 19–23. [Nechaeva GI, Viktorova IА, Druk IV. Displaziya soedinitel’noj tkani: rasprostranennost’, fenotipicheskie priznaki, associacii s drugimi zabolevaniyami. Vrach. 2006;(1):19-23. (In Russ.)]
  11. Нечаева Г.И., Викторова И.А. Дисплазия соединительной ткани: терминология, диагностика, тактика ведения пациентов. – Омск: Тип. БЛАНКОМ, 2007. – 188 с. [Nechaeva GI, Viktorova IA. Displaziya soedinitel’noj tkani: terminologiya, diagnostika, taktika vedeniya pacientov. Omsk: Tip. Blankom; 2006. 188 р. (In Russ.)]

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