Microbiome and urine microbiota: modern concepts and gender features

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The review article provides definitions and presents current data on the biological significance of the microbiome and microbiota of urine. The urinary microbiota is less well understood than the intestinal microbiota, but its biological role is complex and multifaceted. To date, its importance in the formation of colonization resistance, which prevents the invasion of uropathogens, is obvious. An analysis of methods for assessing the microbiome and microbiota of urine was carried out. The shortcomings of widely used standard microbiological research methods are shown. The method of 16S rRNA gene sequencing is described in detail. Information about the gender characteristics of the urine microbiota and the results of its study in healthy women and men are given. Further progress in the study of the urobiome is associated with the acquisition of new technologies for genomic research and the development of bioinformatics.

作者简介

Margarita Slesarevskaya

Academician I.P. Pavlov First St. Petersburg State Medical University

编辑信件的主要联系方式.
Email: mns-1971@yandex.ru
ORCID iD: 0000-0002-4911-6018
SPIN 代码: 9602-7775
Scopus 作者 ID: 57196117211

Cand. Sci. (Med.), Senior Researcher

俄罗斯联邦, Saint Petersburg

Igor Kuzmin

Academician I.P. Pavlov First St. Petersburg State Medical University

Email: kuzminigor@mail.ru
ORCID iD: 0000-0002-7724-7832
SPIN 代码: 2684-4070
Scopus 作者 ID: 56878681300

Dr. Sci. (Med.), Professor of the Department of Urology

俄罗斯联邦, Saint Petersburg

Kairkhan Zhumadillayev

Academician I.P. Pavlov First St. Petersburg State Medical University

Email: kairyoyo@mail.ru

Student

俄罗斯联邦, Saint Petersburg

Gleb Vvedenskiy

Academician I.P. Pavlov First St. Petersburg State Medical University

Email: vvedenskiy.99@mail.ru

Student

俄罗斯联邦, Saint Petersburg

Yury Mikheev

Academician I.P. Pavlov First St. Petersburg State Medical University

Email: Mikheevyra@gmail.com

Student

俄罗斯联邦, Saint Petersburg

Albina Maksimova

Academician I.P. Pavlov First St. Petersburg State Medical University

Email: maksimova_av77@mail.ru
ORCID iD: 0000-0002-5627-2596

Student

俄罗斯联邦, Saint Petersburg

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版权所有 © Slesarevskaya M.N., Kuzmin I.V., Zhumadillayev K.G., Vvedenskiy G.A., Mikheev Y.А., Maksimova A.V., 2022

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