Modern possibilities of allergy diagnostics in real clinical practice
- 作者: Novik G.1, Tamrazova O.2, Zhdanova M.1, Tamrazova A.3, Filimonova O.4
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隶属关系:
- Saint Petersburg State Pediatric Medical University
- Peoples' Friendship University of Russia
- Central State Medical Academy of Department of Presidential Affairs
- International pharmaceutical company "Innovatsionnye immunnye tekhnologii"
- 期: 卷 21, 编号 2 (2024)
- 页面: 321-332
- 栏目: Case reports
- URL: https://journals.rcsi.science/raj/article/view/260066
- DOI: https://doi.org/10.36691/RJA16937
- ID: 260066
如何引用文章
详细
More than 20% of people worldwide suffer from allergic diseases. The high prevalence and wide range of provocative factors, which are increasing daily, complicate the diagnostic search. On the one hand, this leads to inadequately extensive dietary and lifestyle restrictions that reduce the quality of life for patients; on the other hand, it results in the failure to identify life-threatening allergens. The discovery of immunoglobulin E over 60 years ago initiated the search for specific biomarkers to etermine the causes of allergic diseases. Traditional methods of allergen diagnostics have several limitations that hinder the search for potential allergic disease triggers.
The article discusses modern laboratory approaches to multicomponent molecular allergen diagnostics, describes its differences from traditional diagnostic methods, and analyzes the advantages, prospects, limitations, and shortcomings of this method. It also presents a comparative characterization of the test systems available today.
The article presents four clinical cases that demonstrate the capabilities of the multicomponent ALEX 2 test system in diagnostics, choice of therapy tactics, and in forming further personalized recommendations for patients suffering from various allergic diseases.
作者简介
Gennady Novik
Saint Petersburg State Pediatric Medical University
编辑信件的主要联系方式.
Email: ga_novik@mail.ru
ORCID iD: 0000-0002-7571-5460
SPIN 代码: 6289-0209
MD, Dr. Sci. (Med), Professor
俄罗斯联邦, Saint PetersburgOlga Tamrazova
Peoples' Friendship University of Russia
Email: anait_tamrazova@mail.ru
ORCID iD: 0000-0003-3261-6718
SPIN 代码: 5476-8497
MD, Dr. Sci. (Med), Professor
俄罗斯联邦, MoscowMarina Zhdanova
Saint Petersburg State Pediatric Medical University
Email: zhdanova-marina@rambler.ru
ORCID iD: 0000-0001-7035-0100
SPIN 代码: 2204-3465
MD, Cand. Sci. (Med.), Assistant Professor
Saint PetersburgAnait Tamrazova
Central State Medical Academy of Department of Presidential Affairs
Email: anaittamrazova@gmail.com
ORCID iD: 0000-0002-4672-697X
SPIN 代码: 1563-1190
MD
Olga Filimonova
International pharmaceutical company "Innovatsionnye immunnye tekhnologii"
Email: ofilimonova.iit@gmail.com
ORCID iD: 0000-0001-9660-464X
SPIN 代码: 7127-9906
俄罗斯联邦, Moscow
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