Remodeling of the bioelectric activity of the brain in the outcome of cortical resection
- Authors: Astakhova E.A.1, Marchenko E.V.1, Chukhlovin A.A.1, Aleksandrov M.V.1,2
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Affiliations:
- Almazov National Medical Research Center
- S.M. Kirov Military Medical Academy
- Issue: Vol 13, No 1 (2022)
- Pages: 19-24
- Section: Original studies
- URL: https://journals.rcsi.science/pediatr/article/view/108307
- DOI: https://doi.org/10.17816/PED13119-24
- ID: 108307
Cite item
Abstract
Background: The total scalp electrorencephalography shows the activity of groups of cortical neurons. But each of these groups does not exist in isolation, but they are influenced by other areas, both cortical and subcortical systems of the brain. In the course of neurosurgical treatment, patients underwent resection of cortical areas in which the epileptiform focus was located. In patients with resection of the temporal lobe with structural drug-resistant epilepsy, EEG patterns of “loss of activity” are not recorded above the remote areas.
Aim: to study the mechanisms underlying the formation of electrorencephalography patterns recorded in the projection of the resected temporal lobe of the brain in patients operated on for focal drug-resistant epilepsy.
Materials and methods: There were examined 22 patients with structural pharmacoresistant epilepsy. Coherent analysis of the electrorencephalography was performed for an epoch of 30 seconds in transverse and longitudinal intrahemispheric pairs of leads.
Results: Correlation interactions between the temporal leads and their surrounding areas are enhanced after removal of the temporal lobe involved in the epileptic system.
Conclusion: The activity recorded in the postoperative period in the projection area on the scalp of the resected area is formed as a result of signal transmission from other departments.
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##article.viewOnOriginalSite##About the authors
Ekaterina A. Astakhova
Almazov National Medical Research Center
Author for correspondence.
Email: katastakhva@gmail.com
Resident of the Department of Internal Diseases
Russian Federation, Saint PetersburgElena V. Marchenko
Almazov National Medical Research Center
Email: lm_sovushka@mail.ru
Functional Diagnostics Doctor, Polenov Neurosurgical Institute
Russian Federation, Saint PetersburgAlexander A. Chukhlovin
Almazov National Medical Research Center
Email: dr.chukhlovin@gmail.com
MD, PhD, Head of the Laboratory of Neurophysiological Monitoring, Polenov Neurosurgical Institute
Russian Federation, Saint PetersburgMikhail V. Aleksandrov
Almazov National Medical Research Center; S.M. Kirov Military Medical Academy
Email: mdoktor@yandex.ru
MD, PhD, Dr. Med. Sci., Professor, Head of Clinical Neurophysiology Department, Polenov Neurosurgical Institute, Head of the Department of Normal Physiology
Russian Federation, Saint Petersburg; Saint PetersburgReferences
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