EXPERIENCE OF TREATMENT OF MALE HYPERTENSION WITH OBESITY, FASTING HYPERGLYCEMIA AND DEFICIENCY OF VITAMIN D

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Vitamin D insufficiency has been registered for almost half the world's population. Among the elderly, this figure reaches 80-90%, in Russia-78-83%. Men's patients of uroandrological profile with obesity, androgen deficiency, infertility and prostate diseases 69 associated with hypogonadism, obesity, insulin resistance and type 2 diabetes, the frequently detected (hormone) deficiency of vitamin D. In addition to the impact on calcium-phosphorous and carbohydrate metabolism, vitamin D deficiency is associated with an increased risk of developing hypertension.

We have investigated male patients on the levels of vitamin D in the blood serum with immunoassay chemiluminescent method on microchasticah (full automatic Architect i2000 Abbot), the value of systolic and diastolic blood pressure (SAD and DAD) defined by a well-known method of Korotkov, fasting glycemia rates investigated by using the gluko-zooksidantmethod, body mass index (BMI) is calculated by the formula Quetelet.

Elimination of vitamin D deficiency using a single succession introduction of 30004000 IU of cholecalciferol to the men of 40-50 years, suffering from different types of pathology, turns out to be effective not only in treating systolic-diastolic hypertension, but also in reducing, as fasting hyperglycemia and overweight.

作者简介

T Filatova

Ryazan State Medical University named after academician I.P. Pavlov

编辑信件的主要联系方式.
Email: tef1972@rambler.ru
Ph 俄罗斯联邦

A Nizov

Ryazan State Medical University named after academician I.P. Pavlov

Email: nizov@rgmu.ru
Ph., M.D. 俄罗斯联邦

V Davydov

Ryazan State Medical University named after academician I.P. Pavlov

Email: davydov.vikt@yandex.ru
Ph., M.D. 俄罗斯联邦

参考

  1. Дефицит витамина D у взрослых: диагностика, лечение и профилактика: клинические рекомендации. Москва, 2015. 75 с.
  2. Плещева А.В., Пигарова Е.А., Дзеранова Л.К. Витамин D и метаболизм: факты, мифы и предубеждения // Ожирение и метаболизм. 2012. № 2. С. 33-42.
  3. Калинченко С.Ю., Тишова Ю.А., Тюзиков И.А., Ворслов Л.О. Ожирение и метаболический синдром у мужчин. Москва: Практическая медицина, 2014. 126 с.
  4. Тишова Ю.А., Ворслов Л.О., Жуков А.Ю., Калинченко С.Ю. Распространенность дефицита D-гормона (25ОНD3) у пациентов с ожирением в России: ретроспективное популяционное исследование. В кн.: Материалы VII Международного конгресса ISSAM. Москва, 2013. С. 78.
  5. Bellastella G., Maiorino M.I., Olita L., Capuano A., Rafaniello C., GiuglianoD. et al. Vitamin D deficiency in type 2 diabetic patients with hypogonadism // J. Sex. Med. 2014. Vol. 11, № 2. P. 536-542.
  6. Lee DM., Tajar A., Pye SR., Boo-nenS., VanderschuerenD., Bouillon R.et al. Association of hypogonadism with vitamin D status: the European Male Ageing Study // Eur. J. Endocrinol. 2012. Vol. 166, № 1. P. 77-85.
  7. Pilz S., Frisch S., Koertke H., Kuhn J., Dreier J., Obermayer-Pietsch B. et al. Effect of vitamin D supplementation on testosterone levels in men // Horm. Metab. Res. 2011. Vol. 43, №3. P. 223-225.
  8. Blomberg Jensen M. Vitamin D metabolism, sex hormones, and male reproductive function // Reproduction. 2012. Vol. 144, № 2. P. 135-152.
  9. Pitman M.S., Cheetham P.J., Hruby G.W., Katz A.E. Vitamin D deficiency in the urological populations single center analysis // J. Urol. 2011. Vol. 186, № 4. P. 1395-1399.
  10. Тюзиков И.А. Гормон D - статус у мужчин с андрологической патологией (пилотное исследование). В кн.: Материалы X конгресса «Мужское здоровье» с Mеждуна-родным участием. Минск, 2014. С. 89-91.
  11. Pittas A.G., Lau J., Hu F.B., Daw-son-Hughes B.The role ofvitamin D and calcium in type 2 diabetes. A systematic revie-wand meta-analysis // J. Clin. Endocrinol. Metab. 2007. Vol. 92, № 6. P. 2017-2029.
  12. Goel R.K., Lal H. Role of vitamin d supplementation in hypertension // Indian J. Clin. Biochem. 2011. Vol. 26, № 1. Р. 88-90.
  13. Zittermann A., Prokop S. The role of vitamin D for cardiovascular disease and overall mortality // Adv. Exp. Med. Biol. 2014. Vol. 810. P. 106-119.
  14. Дудинская Е.Н., Ткачева О.Н. Роль витамина D в развитии артериальной гипертензии // Кардиоваскулярная терапия и профилактика. 2012. Т. 11, № 3. P. 77-81.
  15. Iss Y., Frishman W.H. Vitamin D: a cardioprotective agent? // Cardiol. Rev. 2012. Vol. 20, № 1. Р. 38-44.
  16. Nadir M.A., Szwejkowski B.R., Witham M.D. Vitamin D and cardiovascular prevention // Cardiovasc. Ther. 2010. Vol. 28, № 4. Р. 5-12.

版权所有 © Filatova T.E., Nizov A.A., Davydov V.V., 2017

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