A clinical case of polyneoplasia
- Authors: Akhmetzyanov FA1,2, Valiev NA2, Egorov VI1,2, Burba DV1,2
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Affiliations:
- Kazan State Medical University
- Republican Clinical Oncology Center
- Issue: Vol 99, No 2 (2018)
- Pages: 304-306
- Section: Clinical observations
- URL: https://journals.rcsi.science/kazanmedj/article/view/8425
- DOI: https://doi.org/10.17816/KMJ2018-304
- ID: 8425
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Abstract
Primary multiple neoplasms (polyneoplasia) are among the interesting and insufficiently studied fields of oncology. The term polyneoplasia is usually used for two or more malignant neoplasms in a single patient, which occur synchronously or metachronously. Over the last decade, an increase of primary multiple tumors prevalence has been observed. In 2015 39 195 new cases of primary multiple tumors were registered in Russia and comprised 6.7% of all incident malignant neoplasms. Primary multiple metachronous and primary multiple synchronous tumors with two neoplasms development are observed most often, with three more rarely, and with four or more very rarely. In average, 0.1% of a total number of oncologic patients have at least three malignant neoplasms. Primary multiple tumors of gastrointestinal tract are observed most often. The current article presents a clinical case of four synchronous tumors in a single patient localized in major duodenal papilla, sigmoid, transverse colon and lung.
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##article.viewOnOriginalSite##About the authors
F A Akhmetzyanov
Kazan State Medical University; Republican Clinical Oncology Center
Author for correspondence.
Email: Akhmetzyanov@mail.ru
Kazan, Russia; Kazan, Russia
N A Valiev
Republican Clinical Oncology Center
Email: Akhmetzyanov@mail.ru
Kazan, Russia
V I Egorov
Kazan State Medical University; Republican Clinical Oncology Center
Email: Akhmetzyanov@mail.ru
Kazan, Russia; Kazan, Russia
D V Burba
Kazan State Medical University; Republican Clinical Oncology Center
Email: Akhmetzyanov@mail.ru
Kazan, Russia; Kazan, Russia
References
- Agabekyan G.O., Kropotov M.A., Saprina O.A. et al. Second primary cancer in patients with head and neck squamous cell carcinoma (review of the literature). Sovremennaya onkologiya. 2014; 16 (2): 82–86. (In Russ.)
- Stepanova Yu.A., Kalinin D.V., Vishnevskiy V.A. Multiple primary neoplasms (literature review). Meditsinskaya vizualizatsiya. 2015; (6): 93–102. (In Russ.)
- Billroth T. Die allgemeine Chirurgie, Pathologie und Therapie. Berlin. 1889; 908 p.
- Kaprin A.D., Starinskiy V.V., Petrova G.V. Sostoyanie onkologicheskoy pomoshchi naseleniyu Rossii v 2015 godu. (The state of oncological assistance to the population of Russia in 2015.) Moscow: MNIOI them P.A. Herzen. 2016; 236 p. (In Russ.)
- Сельчук В.Ю., Долгов И.Ю., Попова Т.Н. Проблема первичной множественности злокачественных новообразований в историческом аспекте. Рос. онкол. ж. 1998; (5): 50–55. [Sel'chuk V.Yu., Dolgov I.Yu.,
- Popova T.N. The problem of primary multiplicity of malignant neoplasms in the historical aspect. Rossiyskiy onkologicheskiy zhurnal. 1998; (5): 50–55. (In Russ.)]
- Ma S.K., Zhang H.T., Sun Y.C., Wu L.Y. Synchronous primary cancers of the endometrium and ovary: review of 43 cases. Zhonghua Zhong Liu Za Zhi. 2008; 30 (9): 690–694.
- Pandurengan R.K., Dumont A.G., Araujo D.M. et al. Survival of patients with multiple primary malignancies: a study of 783 patients with gastrointestinal stromal tumor. Ann. Oncol. 2010: 21 (10); 2107–2111. doi: 10.1093/annonc/mdq078.
- Li X., Kang J., Pan Q. et al. Genetic analysis in a patient with nine primary malignant neoplasms: a rare case of Li-Fraumeni syndrome. Oncol. Reports. 2016: 35 (3); 1519–1528. doi: 10.3892/or.2015.4501.
- Ji J., Hemminki K. Incidence of multiple primary malignancies among patients with bone cancers in Sweden. Cancer Res. Clin. Oncol. 2006; 132 (8): 529–535. doi: 10.1007/s00432-006-0100-1.
- Chaturvedi A.K., Engels E.A., Gilbert E.S. et al. Second cancers among 104,760 survivors of cervical cancer: evaluation of long-term risk. J. Natl. Cancer Inst. 2007; 99: 1634–1643. doi: 10.1093/jnci/djm201.
- Gulhan I., Eser S., Yakut C. et al. Second primary gynecologic cancers after breast cancer in Turkish women. Int. J. Gynecol. Cancer. 2009; 19: 648–650. doi: 10.1111/IGC.0b013e3181a12e8b.
- Irimie A., Achimas-Cadariu P., Burz C. et al. Multiple primary malignancies-epidemiological analysis at a Single Tertiary Institution. J. Gastrointest. & Liver Dis. 2010: 19 (1); 69–73. PMID: 20361078.