Pfannenstiel und Quante, Effect of neosalvarsan and germanine on bactericidal activity in rabbit blood. A message to the question of the indirect action of these chemotherapeutic agents. Ztschr. f. Immunitätsf., Bd 88, H 1/2 1936)

Abstract

The authors believe that the decisive role in the chemotherapeutic effect belongs to the organotropy, and not the parasitotropy of the medicinal substance. However, it cannot be denied that the parasite's cell is able to capture the chemotherapeutic substance or its decay products. Therefore, the chemotherapeutic index is an expression, on the one hand, of the weakening of the parasite, and on the other hand, of the strengthening of the protective function of the organism.

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