Clinical value of the determination of anticardial antibodies in patients with acute myocardial infarction
- Authors: Pozdnyak N.D.1, Efremova I.V.1
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Affiliations:
- Department of Clinical Laboratory Diagnostics, Department of Therapy No. 1, Kazan State Pedagogical University named after B. PI. Lenin
- Issue: Vol 63, No 2 (1982)
- Pages: 13-16
- Section: Articles
- URL: https://journals.rcsi.science/kazanmedj/article/view/60388
- DOI: https://doi.org/10.17816/kazmj60388
- ID: 60388
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Abstract
In 281 patients with acute myocardial infarction, the titer of anticardial antibodies was studied using the indirect immunofluorescence method of Koons. With adequate, immunological reactivity, the height of anticardial-antibody titers reflects the extent of necrotic myocardial damage. Their earliest appearance in blood serum (1-2 days of illness) was observed with repeated and recurrent myocardial infarction. Dissociation between the magnitude of necrotic myocardial damage and a low level of anticardial antibodies indicates a "breakdown" of the protective immunological mechanisms and has an unfavorable prognostic value.
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##article.viewOnOriginalSite##About the authors
N. D. Pozdnyak
Department of Clinical Laboratory Diagnostics, Department of Therapy No. 1, Kazan State Pedagogical University named after B. PI. Lenin
Author for correspondence.
Email: info@eco-vector.com
Russian Federation, Kazan, Russia
I. V. Efremova
Department of Clinical Laboratory Diagnostics, Department of Therapy No. 1, Kazan State Pedagogical University named after B. PI. Lenin
Email: info@eco-vector.com
Russian Federation, Kazan, Russia
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