Excretion of 5-oxyindoleacetic acid in rheumatism in children
- Authors: Akhmerova K.S.1
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Affiliations:
- Kazan State Institute for Advanced Medical Training
- Issue: Vol 52, No 2 (1971)
- Pages: 28-29
- Section: Articles
- URL: https://journals.rcsi.science/kazanmedj/article/view/59672
- DOI: https://doi.org/10.17816/kazmj59672
- ID: 59672
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Abstract
According to experimental data, in addition to mediators of the nervous system, biogenic amines play an important role in the development of several inflammatory and allergic reactions, among which serotonin (5-oxytryptamine) is of particular interest. Free serotonin is rapidly oxidised by monoamine oxidase and excreted in the urine as 5-oxyindoleacetic acid (5-OAICA). 5-OAIC accounts for about 50% of serotonin metabolism. The amount of 5-OAIC excreted in the urine is an indication of the intensity of serotonin metabolism in the body.
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##article.viewOnOriginalSite##About the authors
Kh. S. Akhmerova
Kazan State Institute for Advanced Medical Training
Author for correspondence.
Email: info@eco-vector.com
Russian Federation
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