Active immunization with ricinoleate vaccines against acute poliomyelitis
- Authors: R. P.
- Issue: Vol 34, No 2 (1938)
- Pages: 211-212
- Section: Articles
- URL: https://journals.rcsi.science/kazanmedj/article/view/54595
- DOI: https://doi.org/10.17816/kazmj54595
- ID: 54595
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Abstract
Showed on a very large number of monkeys that a 5-10-fold injection of ricinoleate vaccine under the skin (0.05-1 cm3 per 1 kg of body weight) protects animals from disease in 61-76% of cases with subsequent intracerebral administration of the virus poliomyelitis; ѵ of all control (not immunized) monkeys developed paralysis on the 5-8th day. The same effect was obtained when the studied vaccine was administered intradermally.
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