Eating disorders in preschool and primary school children with autism spectrum disorder and its clinical significance

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Abstract

Autism spectrum disorder is the fastest growing form of nervous and mental development disorder in the world. In this regard, there is a special need to resolve issues of diagnosis and correction of not only the main symptoms of this disease, but also numerous associated somatic disorders. One of the common clinical manifestations in children with autism spectrum disorder is pathological eating behavior, which includes disturbances in eating habits and preferences, frequency of meals, etc. Despite the fact that eating disorders can also occur among normotypical coevals, in children with autism spectrum disorder, these manifestations are clinically more diverse, vary in severity and often appear earlier than the main symptoms of the disease. It must be emphasized that the correction of certain nutritional disorders in this group of children is often difficult due to the characteristics of the course of the underlying disease. This may be further exacerbated by increased parental anxiety. A timely solution to the problem of eating behavior in children with autistic disorder is of great importance for strengthening their health and reducing the severity of the underlying disease, since the connection between neuropsychic and somatic health is inseparable. In the review, we tried to identify the main factors involved in the formation of eating disorders in children with autism spectrum disorder, and presented existing practical tools for analyzing this medical problem and managing their nutrition for preventive and therapeutic purposes.

About the authors

Nataliya A. Smolko

Kazan State Medical University; Kazan (Volga Region) Federal University

Author for correspondence.
Email: sna997@yandex.ru
ORCID iD: 0009-0004-2749-4001
SPIN-code: 7308-4190

PhD Stud., Depart. of Propaedeutics of Children's Diseases and Faculty Pediatrics; Junior Researcher, Research Laboratory “Gene and cell technologies”

Russian Federation, Kazan; Kazan

Rezeda A. Fayzullina

Kazan State Medical University; Kazan (Volga Region) Federal University

Email: r868@mail.ru
ORCID iD: 0000-0002-7209-5737
SPIN-code: 3435-5952
Scopus Author ID: 57189341335

D. Sci. (Med.), Prof., Head of Depart., Depart. of Propaedeutics of Children's Diseases and Faculty Pediatrics; Leading Researcher, Research Laboratory “Neurocognitive Research”

Russian Federation, Kazan; Kazan

Yana O. Mukhamedshina

Kazan State Medical University; Kazan (Volga Region) Federal University

Email: yana.k-z-n@mail.ru
ORCID iD: 0000-0002-9435-340X
SPIN-code: 8569-9002

D. Sci. (Med.), Assoc. Prof., Depart. of Histology, Cytology and Embryology, Kazan State Medical University, Kazan, Russia; Leading Researcher, Research Laboratory “Gene and cell technologies”

Russian Federation, Kazan; Kazan

References

  1. Hornberger LL, Lane MA; Committee on adolescence. Identification and management of eating disorders in children and adolescents. Pediatrics. 2021;147(1):e2020040279. doi: 10.1542/peds.2020-040279.
  2. Kjeldbjerg ML, Clausen L. Prevalence of binge-eating disorder among children and adolescents: A systematic review and meta-analysis. Eur Child Adolesc Psychiatry. 2023;32(4):549–574. doi: 10.1007/s00787-021-01850-2.
  3. Stabouli S, Erdine S, Suurorg L, Jankauskienė A, Lurbe E. Obesity and eating disorders in children and adolescents: The bidirectional link. Nutrients. 2021;13(12):4321. doi: 10.3390/nu13124321.
  4. Datta N, Matheson BE, Citron K, Van Wye EM, Lock JD. Evidence based update on psychosocial treatments for eating disorders in children and adolescents. J Clin Child Adolesc Psychol. 2023;52(2):159–170. doi: 10.1080/15374416.2022.2109650.
  5. DeCosta P, Moller P, Frost MB, Olsen A. Changing children’s eating behaviour — a review of experimental research. Appetite. 2017;113:327–357. doi: 10.1016/j.appet.2017.03.004.
  6. Galmiche M, Déchelotte P, Lambert G, Tavolacci MP. Prevalence of eating disorders over the 2000–2018 period: A systematic literature review. Am J Clin Nutr. 2019;109(5):1402–1413. doi: 10.1093/ajcn/nqy342.
  7. Margari L, Marzulli L, Gabellone A, de Giambattista C. Eating and mealtime behaviors in patients with autism spectrum disorder: Current perspectives. Neuropsychiatr Dis Treat. 2020;16:2083–2102. doi: 10.2147/NDT.S224779.
  8. Baraskewich J, von Ranson KM, McCrimmon A, McMorris CA. Feeding and eating problems in children and adolescents with autism: A scoping review. Autism. 2021;25(6):1505–1519. doi: 10.1177/1362361321995631.
  9. Petitpierre G, Luisier AC, Bensafi M. Eating behavior in autism: Senses as a window towards food acceptance. Curr Opin Food Sci. 2021;41:210–216. doi: 10.1016/j.cofs.2021.04.015.
  10. Tkachuk EA, Martynovich NN, Globenko NE. Features of the nutritional status and nutrition of children with autistic disorders. Voprosy pitaniia. 2021;90(5):67–76. (In Russ.) doi: 10.33029/0042-8833-2021-90-5-67-76.
  11. Krigsman A. Gastrointestinal pathology in autism: Description and treatment. Medical Veritas. 2007;(4):1522–1530.
  12. Buie T, Campbell DB, Fuchs III GJ, Furuta GT, Levy J, VandeWater J, Winter H. Evaluation, diagnosis, and treatment of gastrointestinal disorders in individuals with ASDs: A consensus report. Pediatrics. 2010;125(1):S1–S18. doi: 10.1542/peds.2009-1878C.
  13. Madra M, Ringel R, Margolis KG. Gastrointestinal issues and autism spectrum disorder. Child Adolesc Psychiatr Clin N Am. 2020;29(3):501–513. doi: 10.1016/j.chc.2020.02.005.
  14. Marí-Bauset S, Zazpe I, Mari-Sanchis A, Llopis-González A, Morales-Suárez-Varela M. Food selectivity in autism spectrum disorders: A systematic review. J Child Neurol. 2014;29(11):1554–61. doi: 10.1177/0883073813498821.
  15. Numata N, Nakagawa A, Yoshioka K, Isomura K, Matsuzawa D, Setsu R, Nakazato M, Shimizu E. Associations between autism spectrum disorder and eating disorders with and without self-induced vomiting: An empirical study. J Eat Disord. 2021;9(1):5. doi: 10.1186/s40337-020-00359-4.
  16. Carpita B, Muti D, Cremone IM, Fagiolini A, Dell'Osso L. Eating disorders and autism spectrum: links and risks. CNS Spectr. 2022;27(3):272–280. doi: 10.1017/S1092852920002011.
  17. Paterson H, Peck K. Sensory processing ability and eating behaviour in children with autism. J Hum Nutr Diet. 2011;24(3):301–301. doi: 10.1111/j.1365-277X.2011.01175_31.x.
  18. Lane AE, Geraghty ME, Young GS, Rostorfer JL. Problem eating behaviors in autism spectrum disorder are associated with suboptimal daily nutrient intake and taste/smell sensitivity. ICAN: Infant, Child & Adolescent Nutrition. 2014;6(3):172–180. doi: 10.1177/1941406414523981.
  19. Hubbard KL, Anderson SE, Curtin C, Must A, Bandini LG. A comparison of food refusal related to characteristics of food in children with autism spectrum disorder and typically developing children. J Acad Nutr Diet. 2014;114(12):1981–1987. doi: 10.1016/j.jand.2014.04.017.
  20. Zulkifli FNA, Rahman PA. Relationships between sensory processing disorders with feeding behavior problems among children with autism spectrum disorder. Mal J Med Health Sci. 2021;17(Supppl 3):230–236.
  21. Nadon G, Feldman D, Gisel E. Feeding issues associated with the autism spectrum disorders. In: Recent Advances in Autism Spectrum Disorders. Vol. 1. InTech; 2013. p. 601–602. doi: 10.5772/53644.
  22. Robertson CE, Baron-Cohen S. Sensory perception in autism. Nat Rev Neurosci. 2017;18(11):671–684. doi: 10.1038/nrn.2017.112.
  23. Raspini B, Prosperi M, Guiducci L, Santocchi E, Tancredi R, Calderoni S, Morales MA, Morelli M, Simione M, Fiechtner L, Muratori F, Cena H. Dietary patterns and weight status in Italian preschoolers with autism spectrum disorder and typically developing children. Nutrients. 2021;13(11):4039. doi: 10.3390/nu13114039.
  24. Chen N, Watanabe K, Kobayakawa T, Wada M. Relationships between autistic traits, taste preference, taste perception, and eating behaviour. Eur Eat Disord Rev. 2022;30(5):628–640. doi: 10.1002/erv.2931.
  25. Molloy CA, Manning-Courtney P. Prevalence of chronic gastrointestinal symptoms in children with autism and autistic spectrum disorders. Autism. 2003;7:165–171. doi: 10.1177/1362361303007002004.
  26. Vissoker RE, Latzer Y, Gal E. Eating and feeding problems and gastrointestinal dysfunction in autism spectrum disorders. Res Autism Spectr Disord. 2015;12:10–21. doi: 10.1016/j.rasd.2014.12.010.
  27. Holingue C, Kalb LG, Musci R, Lukens C, Lee L-C, Kaczaniuk J, Landrum M, Buie T, Fallin MD. Characteristics of the autism spectrum disorder gastrointestinal and related behaviors inventory in children. Autism Res. 2022;15(6):1142–1155. doi: 10.1002/aur.2707.
  28. Schwartz MW, Woods SC, Porte D Jr, Seeley RJ, Baskin DG. Central nervous system control of food intake. Nature. 2000;404(6778):661–671. doi: 10.1038/35007534.
  29. Berthoud H, Münzberg H, Richards B, Morrison C. Neural and metabolic regulation of macronutrient intake and selection. Proc Nutr Soc. 2012;71(3):390–400. doi: 10.1017/S0029665112000559.
  30. Sohn JW, Elmquist JK, Williams KW. Neuronal circuits that regulate feeding behavior and metabolism. Trends Neurosci. 2013;36(9):504–512. doi: 10.1016/j.tins.2013.05.003.
  31. Hao S, Yang Y, Helmy M, Wang H. Neural regulation of feeding behavior. Adv Exp Med Biol. 2020;1284:23–33. doi: 10.1007/978-981-15-7086-5_3.
  32. Wolfe FH, Auzias G, Deruelle C, Chaminade T. Focal atrophy of the hypothalamus associated with third ventricle enlargement in autism spectrum disorder. Neuroreport 2015;26:1017–1022. doi: 10.1097/WNR.0000000000000461.
  33. Caria A, Ciringione L, Falco S. Morphofunctional alterations of the hypothalamus and social behavior in autism spectrum disorders. Brain Sci. 2020;10(7):435. doi: 10.3390/brainsci10070435.
  34. Adamska-Patruno E, Ostrowska L, Goscik J, Pietraszewska B, Kretowski A, Gorska M. The relationship between the leptin/ghrelin ratio and meals with various macronutrient contents in men with different nutritional status: a randomized crossover study. Nutr J. 2018;17(1):118. doi: 10.1186/s12937-018-0427-x.
  35. Dhaliwal KK, Orsso CE, Richard C, Haqq AM, Zwaigenbaum L. Risk factors for unhealthy weight gain and obesity among children with autism spectrum disorder. Int J Mol Sci. 2019;20(13):3285. doi: 10.3390/ijms20133285.
  36. Carmassi C, Palagini L, Caruso D, Masci I, Nobili L, Vita A, Dell'Osso L. Systematic review of sleep disturbances and circadian sleep desynchronization in autism spectrum disorder: Toward an integrative model of a self-reinforcing loop. Front Psychiatry. 2019;10:366. doi: 10.3389/fpsyt.2019.00366.
  37. Missig G, McDougle CJ, Carlezon WA Jr. Sleep as a translationally — relevant endpoint in studies of autism spectrum disorder (ASD). Neuropsychopharmacology. 2020;45(1):90–103. doi: 10.1038/s41386-019-0409-5.
  38. Olivo G, Wiemerslage L, Swenne I, Zhukowsky C, Salonen-Ros H, Larsson EM, Gaudio S, Brooks SJ, Schiöth HB. Limbic-thalamo-cortical projections and reward-related circuitry integrity affects eating behavior: A longitudinal DTI study in adolescents with restrictive eating disorders. PLoS One. 2017;12(3):e0172129. doi: 10.1371/journal.pone.0172129.
  39. Wegiel J, Flory M, Schanen NC, Cook EH, Nowicki K, Kuchna I, Imaki H, Ma SY, Wegiel J, London E, Casanova MF, Wisniewski T, Brown WT. Significant neuronal soma volume deficit in the limbic system in subjects with 15q11.2–q13 duplications. Acta Neuropathol Commun. 2015;3:63. doi: 10.1186/s40478-015-0241-z.
  40. Weidenheim KM, Goodman L, Dickson DW, Gillberg C, Rästam M, Rapin I. Etiology and pathophysiology of autistic behavior: Clues from two cases with an unusual variant of neuroaxonal dystrophy. J Child Neurol. 2001;16(11):809–819. doi: 10.1177/08830738010160110601.
  41. Emond A, Emmett P, Steer C, Golding J. Feeding symptoms, dietary patterns, and growth in young children with autism spectrum disorders. Pediatrics. 2010;126:e337–e342. doi: 10.1542/peds.2009-2391.
  42. Mayes SD, Zickgraf H. Atypical eating behaviors in children and adolescents with autism, ADHD, other disorders, and typical development. Res Autism Spectr Disord. 2019;64:76–83. doi: 10.1016/j.rasd.2019.04.002.
  43. Benninga MA, Faure C, Hyman PE, St James Roberts I, Schechter NL, Nurko S. Childhood functional gastrointestinal disorders: Neonate/toddler. Gastroenterology. 2016:S0016-5085(16)00182-7. doi: 10.1053/j.gastro.2016.02.016.
  44. Chogle A, Velasco-Benitez CA, Koppen IJ, Moreno JE, Ramírez Hernández CR, Saps M. A population-based study on the epidemiology of functional gastrointestinal disorders in young children. J Pediatr. 2016;179:139–143.e1. doi: 10.1016/j.jpeds.2016.08.095.
  45. Salvatore S, Baldassarre ME, Di Mauro A, Laforgia N, Tafuri S, Bianchi FP, Dattoli E, Morando L, Pensabene L, Meneghin F, Dilillo D, Mancini V, Talarico V, Tandoi F, Zuccotti G, Agosti M. Neonatal antibiotics and prematurity are associated with an increased risk of functional gastrointestinal disorders in the first year of life. J Pediatr. 2019;212:44–51. doi: 10.1016/j.jpeds.2019.04.061.
  46. Walter AW, Hovenkamp A, Devanarayana NM, Solanga R, Rajindrajith S, Benninga MA. Functional constipation in infancy and early childhood: epidemiology, risk factors, and healthcare consultation. BMC Pediatr. 2019;19:285. doi: 10.1186/s12887-019-1652-y.
  47. Indrio F, Enninger A, Aldekhail W, Al-Ghanem G, Al-Hussaini A, Al-Hussaini B, Al-Refaee F, Al-Said K, Eid B, Faysal W, Hijazeen R, Isa HMA, Onkarappa D, Rawashdeh M, Rohani P, Sokhn M. Management of the most common functional gastrointestinal disorders in infancy: The Middle East Expert Consensus. Pediatr Gastroenterol Hepatol Nutr. 2021;24(4):325–336. doi: 10.5223/pghn.2021.24.4.325.
  48. Beser OF, Cullu Cokugras F, Dogan G, Akgun O, Elevli M, Yilmazbas P, Vandenplas Y. The frequency of and factors affecting functional gastrointestinal disorders in infants that presented to tertiary care hospitals. Eur J Pediatr. 2021;180(8):2443–2452. doi: 10.1007/s00431-021-04059-2.
  49. Souza NC, Mendonca JN, Portari GV, Jordao AA Jr, Marchini JS, Chiarello PG. Intestinal permeability and nutritional status in developmental disorders. Altern Ther Health Med. 2012;18:19–24. PMID: 22516881.
  50. McElhanon BO, McCracken C, Karpen S, Sharp WG. Gastrointestinal symptoms in autism spectrum disorder: A meta-analysis. Pediatrics. 2014;133:872–883. doi: 10.1542/peds.2013-3995.
  51. Valenzuela-Zamora AF, Ramírez-Valenzuela DG, Ramos-Jiménez A. Food selectivity and its implications associated with gastrointestinal disorders in children with autism spectrum disorders. Nutrients. 2022;14:2660. doi: 10.3390/nu14132660.
  52. Wolpert KH, Kim S-J, Kodish I, Uspal NG. Medical management of children with autism in the emergency department. Pediatr Emerg Care. 2022;38:462–463. doi: 10.1097/PEC.0000000000002751.
  53. Ibrahim SH, Voigt RG, Katusic SK, Weaver AL, Barbaresi WJ. Incidence of gastrointestinal symptoms in children with autism: A population-based study. Pediatrics. 2009;124(2):680–686. doi: 10.1542/peds.2008-2933.
  54. Holingue C, Newill C, Lee L, Pasricha PJ, Daniele Fallin M. Gastrointestinal symptoms in autism spectrum disorder: A review of the literature on ascertainment and prevalence. Autism Res. 2018;11:24–36. doi: 10.1002/aur.1854.
  55. Ristori MV, Quagliariello A, Reddel S, Ianiro G, Vicari S, Gasbarrini A, Putignani L. Autism, gastrointestinal symptoms and modulation of gut microbiota by nutritional interventions. Nutrients. 2019;11(11):2812. doi: 10.3390/nu11112812.
  56. Khalil M, Azouz HG, Ahmed SA, Gad HA, Omar OM. Sensory processing and gastrointestinal manifestations in autism spectrum disorders: No relation to Clostridium difficile. J Mol Neurosci. 2021;71:153–161. doi: 10.1007/s12031-020-01636-2.
  57. Mazefsky CA, Schreiber DR, Olino TM, Minshew NJ. The association between emotional and behavioral problems and gastrointestinal symptoms among children with high-functioning autism. Autism. 2014;18:493–501. doi: 10.1177/1362361313485164.
  58. Jiang X, Matson JL, Cervantes PE, Matheis M, Burns CO. Gastrointestinal issues in infants and children with autism and developmental delays. J Dev Phys Disabil. 2017;29:407–47. doi: 10.1007/s10882-017-9532-6.
  59. Restrepo B, Angkustsiri K, Taylor SL, Rogers SJ, Cabral J, Heath B, Hechtman A, Solomon M, Ashwood P, Amaral DG, Nordahl CW. Developmental-behavioral profiles in children with autism spectrum disorder and co-occurring gastrointestinal symptoms. Autism Res. 2020;13(10):1778–1789. doi: 10.1002/aur.2354.
  60. Chaidez V, Hansen RL, Hertz-Picciotto I. Gastrointestinal problems in children with autism, developmental delays or typical development. J Autism Dev Disord. 2014;44:1117–1127. doi: 10.1007/s10803-013-1973-x.
  61. Penzol MJ, Salazar de Pablo G, Llorente C, Moreno C, Hernández P, Dorado ML, Parellada M. Functional gastrointestinal disease in autism spectrum disorder: A retrospective descriptive study in a clinical sample. Front Psychiatry. 2019;10:179. doi: 10.3389/fpsyt.2019.00179.
  62. Mannion A, Leader G. An analysis of the predictors of comorbid psychopathology, gastrointestinal symptoms and epilepsy in children and adolescents with autism spectrum disorder. Res Autism Spectr Disord. 2013;7:1663–1671. doi: 10.1016/j.rasd.2013.10.002.
  63. Valicenti-McDermott MD, McVicar K, Cohen HJ, Wershil BK, Shinnar S. Gastrointestinal symptoms in children with an autism spectrum disorder and language regression. Pediatr Neurol. 2008;39:392–398. doi: 10.1016/j.pediatrneurol.2008.07.019.
  64. Srikantha P, Mohajeri MH. The possible role of the microbiota-gut-brain-axis in autism spectrum disorder. Int J Mol Sci. 2019;20:2115. doi: 10.3390/ijms20092115.
  65. Tomova A, Husarova V, Lakatosova S, Bakos J, Vlkova B, Babinska K, Ostatnikova D. Gastrointestinal microbiota in children with autism in Slovakia. Physiol Behav. 2015;138:179–187. doi: 10.1016/j.physbeh.2014.10.033.
  66. Leader G, Abberton C, Cunningham S, Gilmartin K, Grudzien M, Higgins E, Joshi L, Whelan S, Mannion A. Gastrointestinal symptoms in autism spectrum disorder: A systematic review. Nutrients. 2022;14(7):1471. doi: 10.3390/nu14071471.
  67. Settanni CR, Bibbò S, Ianiro G, Rinninella E, Cintoni M, Mele MC, Cammarota G, Gasbarrini A. Gastrointestinal involvement of autism spectrum disorder: focus on gut microbiota. Expert Rev Gastroenterol Hepatol. 2021;15(6):599–622. doi: 10.1080/17474124.2021.1869938.
  68. Parracho HMRT, Bingham MO, Gibson GR, McCartney AL. Differences between the gut microflora of children with autistic spectrum disorders and that of healthy children. J Med Microbiol. 2005;54:987–991. doi: 10.1099/jmm.0.46101-0.
  69. Madore C, Leyrolle Q, Lacabanne C, Benmamar-Badel A, Joffre C, Nadjar A, Layé S. Neuroinflammation in autism: Plausible role of maternal inflammation, dietary omega 3, and microbiota. Neural Plast. 2016;2016:3597209. doi: 10.1155/2016/3597209.
  70. Jenkins TA, Nguyen JC, Polglaze KE, Bertrand PP. Influence of tryptophan and serotonin on mood and cognition with a possible role of the gut-brain axis. Nutrients. 2016;8(1):56. doi: 10.3390/nu8010056.
  71. Sharp PB, Miller GA, Heller W. Transdiagnostic dimensions of anxiety: Neural mechanisms, executive functions, and new directions. Int J Psychophysiol. 2015;98:365. doi: 10.1016/j.ijpsycho.2015.07.001.
  72. Damiano SR, Yager Z, McLean SA, Paxton SJ. Achieving body confidence for young children: Development and pilot study of a universal teacher-led body image and weight stigma program for early primary school children. Eat Disord. 2018;26:487–504. doi: 10.1080/10640266.2018.1453630.
  73. McCabe MP, Vincent MA. The role of biodevelopmental and psychological factors in disordered eating among adolescent males and females. Eur Eat Disord Rev. 2003;11:315–328. doi: 10.1002/erv.500.
  74. Nickel K, Maier S, Endres D, Joos A, Maier V, Tebartz van Elst L, Zeeck A. Systematic review: Overlap between eating, autism spectrum, and attention-deficit/hyperactivity disorder. Front Psychiatry. 2019;10:708. doi: 10.3389/fpsyt.2019.00708.
  75. Bandini LG, Anderson SE, Curtin C, Cermak S, Evans EW, Scampini R, Maslin M, Must A. Food selectivity in children with autism spectrum disorders and typically developing children. J Pediatr. 2010;157(2):259–264. doi: 10.1016/j.jpeds.2010.02.013.
  76. Zulkifli MN, Kadar M, Fenech M, Hamzaid NH. Interrelation of food selectivity, oral sensory sensitivity, and nutrient intake in children with autism spectrum disorder: A scoping review. Res Autism Spectr Disord. 2022;93:101928. doi: 10.1016/j.rasd.2022.101928.
  77. Schreck KA, Williams K, Smith AF. A comparison of eating behaviors between children with and without autism. J Autism Dev Disord. 2004;34:433–438. doi: 10.1023/B:JADD.0000037419.78531.86.
  78. Sizoo B, van den Brink W, Franke B, Vasquez AA, van Wijngaarden-Cremers P, van der Gaag RJ. Do candidate genes discriminate patients with an autism spectrum disorder from those with attention deficit/hyperactivity disorder and is there an effect of lifetime substance use disorders? World J Biol Psychiatry. 2010;11:699–708. doi: 10.3109/15622975.2010.480985.
  79. Ledford JR, Gast DL. Feeding problems in children with autism spectrum disorders: A review. Focus Autism Other Dev Disabl. 2006;21:153–166. doi: 10.1177/10883576060210030401.
  80. Turner-Brown L, Frisch M. Understanding and addressing restricted and repetitive behaviors in children with autism. In: Vivanti G, Bottema-Beutel K, Turner-Brown L, editors. Clinical Guide to Early Interventions for Children with Autism. Best Practices in Child and Adolescent Behavioral Health Care. Cham: Springer; 2020. p. 61–77. doi: 10.1007/978-3-030-41160-2_4.
  81. Taylor CM, Wernimont SM, Northstone K, Emmett PM. Picky/fussy eating in children: Review of definitions, assessment, prevalence and dietary intakes. Appetite. 2015;95:349–359. doi: 10.1016/j.appet.2015.07.026.
  82. Archer LA, Rosenbaum PL, Streiner DL. The children’s eating behavior inventory: Reliability and validity results. J Pediatr Psychol. 1991;16:629–642. doi: 10.1093/jpepsy/16.5.629.
  83. DeMand A, Johnson C, Foldes E. Psychometric properties of the brief autism mealtime behaviors inventory. J Autism Dev Disord. 2015;45:2667–2673. doi: 10.1007/s10803-015-2435-4.
  84. Gal E, Gal-Mishael R, Vissoker RE, Hedley D, Bury SM, Stolar O. Eating challenges in children with autism spectrum disorder: Development and validation of the “Aut-Eat” Questionnaire (AEQ). J Autism Dev Disord. 2022;52(2):811–822. doi: 10.1007/s10803-021-04978-x.
  85. Jaafar NH, Othman A, Majid NA, Harith S, Zabidi-Hussin Z. Parent-report instruments for assessing feeding difficulties in children with neurological impairments: A systematic review. Dev Med Child Neurol. 2019;61:135–144. doi: 10.1111/dmcn.13986.
  86. Nakaoka K, Tateyama K, Kurasawa S, Tanabe H, Takabatake S. Validity and reliability of the questionnaire for measuring mealtime behavior in children with autism spectrum disorder. Japanese Occup Ther Res. 2019;38:151–162. doi: 10.32178/jotr.38.2_151.
  87. Nakaoka K, Tanba H, Yuri T, Tateyama K, Kurasawa S. Convergent validity of the Autism Spectrum Disorder Mealtime Behavior Questionnaire (ASD-MBQ) for children with autism spectrum disorder. PLoS One. 2022;17:e0267181. doi: 10.1371/journal.pone.0267181.
  88. Senyueva LV, Dovzhenko AYu. Influence of child-parent relations on the food behavior of a child. Tribuna Uchenogo. 2020;(12):998–1005. (In. Russ.) EDN: HBUORD.
  89. Bryant-Waugh R, Markham L, Kreipe RE, Walsh BT. Feeding and eating disorders in childhood. Int J Eat Disord. 2010;43:98–111. doi: 10.1002/eat.20795.
  90. Ahumada D, Guzmán B, Rebolledo S, Opazo K, Marileo L, Parra-Soto S, Viscardi S. Eating patterns in children with autism spectrum disorder. Healthcare (Basel). 2022;10(10):1829. doi: 10.3390/healthcare10101829.
  91. Bandini LG, Curtin C, Phillips S, Anderson SE, Maslin M, Must A. Changes in food selectivity in children with autism spectrum disorder. J Autism Dev Disord. 2017;47:439–446. doi: 10.1007/s10803-016-2963-6.
  92. Pavlovskaya EV. Selective appetite in children. Current Pediatrics. 2013;12(6):10–18. (In Russ.) doi: 10.15690/vsp.v12i6.868.
  93. Damiano CR, Aloi J, Burrus C, Garbutt JC, Kampov-Polevoy AB, Dichter GS. Intact hedonic responses to sweet tastes in autism spectrum disorder. Res Autism Spectr Disord. 2014;8:230–236. doi: 10.1016/j.rasd.2013.12.003.
  94. Riccio MP, Franco C, Negri R, Ferrentino RI, Maresca R, D'alterio E, Greco L, Bravaccio C. Is food refusal in autistic children related to TAS2R38 genotype? Autism Res. 2018;11(3):531–538. doi: 10.1002/aur.1912.
  95. Ogden CL, Carroll MD, Curtin LR, McDowell MA, Tabak CJ, Flegal KM. Prevalence of overweight and obesity in the United States, 1999–2004. JAMA. 2006;295:1549–1555. doi: 10.1001/jama.295.13.1549.
  96. Ogden CL, Yanovski SZ, Carroll MD, Flegal KM. The epidemiology of obesity. Gastroenterology 2007;132:2087–2102. doi: 10.1053/j.gastro.2007.03.052.
  97. Lebedeva UM, Gmoshinskaya MV, Pyr'eva EA. Nutrition of preschool and school-age children: state of the problem. Farmateka. 2021;28:27–33. (In Russ.)
  98. De Magistris L, Familiari V, Pascotto A, Sapone A, Frolli A, Iardino P, Carteni M, De Rosa M, Francavilla R, Riegler G, Militerni R, Bravaccio C. Alterations of the intestinal barrier in patients with autism spectrum disorders and in their first-degree relatives. J Pediatr Gastroenterol Nutr. 2010;51(4):418–424. doi: 10.1097/MPG.0b013e3181dcc4a5.
  99. Khavkin AI, Vasia MN, Novikova VP. The biological role of casomorphins. Experimental and Clinical Gastroenterology. 2021;(12):102–109. (In Russ.) doi: 10.31146/1682-8658-ecg-196-12-102-109.
  100. Khachatryan LG, Kasanave EV, Geppe NA, Tyurina EN, Kaminskaya TS, Vadiyan DE, Polyanskaya AV, Chebysheva SN, Manukyan MS. Comprehensive evaluation of the effectiveness of gluten-free casein-free diet in children with delayed psycho-speech development. Pediatric Nutrition. 2022;20(2):5–16. (In Russ.) doi: 10.20953/1727-5784-2022-2-5-16.
  101. Bavykina IA, Zvyagin AA, Antakova LN, Gusev KYu. Nutritional status in children with autism spectrum disorders. Pediatric Nutrition. 2019;17:56–61. (In Russ.) doi: 10.20953/1727-5784-2019-1-56-61.
  102. Karhu E, Zukerman R, Eshraghi RS, Mittal J, Deth RC, Castejon AM, Trivedi M, Mittal R, Eshraghi AA. Nutritional interventions for autism spectrum disorder. Nutr Rev. 2020;78(7):515–531. doi: 10.1093/nutrit/nuz092.
  103. Lukens CT, Silverman AH. Systematic review of psychological interventions for pediatric feeding problems. J Pediatr Psychol. 2014;39:903–917. doi: 10.1093/jpepsy/jsu040.
  104. Esposito M, Mirizzi P, Fadda R, Pirollo C, Ricciardi O, Mazza M, Valenti M. Food selectivity in children with autism: Guidelines for assessment and clinical interventions. Int J Environ Res Public Health. 2023;20(6):5092. doi: 10.3390/ijerph20065092.
  105. Reche-Olmedo L, Torres-Collado L, Compañ-Gabucio LM, Garcia-de-la-Hera M. The role of occupational therapy in managing food selectivity of children with autism spectrum disorder: A scoping review. Children 2021;8:1024. doi: 10.3390/children8111024.
  106. Levine SZ, Kodesh A, Viktorin A, Smith L, Uher R, Reichenberg A, Sandin S.. Association of maternal use of folic acid and multivitamin supplements in the periods before and during pregnancy with the risk of autism spectrum disorder in offspring. JAMA Psychiatry. 2018;75(2):176–184. doi: 10.1001/jamapsychiatry.2017.4050.
  107. Zhong C, Tessing J, Lee BK, Lyall K. Maternal dietary factors and the risk of autism spectrum disorders: A systematic review of existing evidence. Autism Res 2020;13:1634–1658. doi: 10.1002/aur.2402.
  108. Indika NR, Frye RE, Rossignol DA, Owens SC, Senarathne UD, Grabrucker AM, Perera R, Engelen MPKJ, Deutz NEP. The rationale for vitamin, mineral, and cofactor treatment in the precision medical care of autism spectrum disorder. J Pers Med. 2023;13(2):252. doi: 10.3390/jpm13020252.
  109. Kittana M, Ahmadani A, Stojanovska L, Attlee A. The role of vitamin D supplementation in children with autism spectrum disorder: a narrative review. Nutrients 2021;14:26. doi: 10.3390/nu14010026.
  110. Safahani M, Aligholi H, Asadi-Pooya AA. Management of antiepileptic drug-induced nutrition-related adverse effects. Neurol Sci. 2020;41:3491–3502. doi: 10.1007/s10072-020-04573-5.
  111. Adams JB, Audhya T, McDonough-Means S, Rubin RA, Quig D, Geis E, Gehn E, Loresto M, Mitchell J, Atwood S, Barnhouse S, Lee W. Effect of a vitamin/mineral supplement on children and adults with autism. BMC Pediatr. 2011;11:111. doi: 10.1186/1471-2431-11-111.

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