Change of electrical impedance measurements on brain in patients with the «dry» form of age-related macular degeneration treated with polarized polychromatic non-coherent light and dynamic electromyostimulation

Aim. To study the change of electrical impedance measurements in brain in patients with the «dry» form of age-related macular degeneration before and after combined treatment with polarized polychromatic non-coherent light and dynamic electromyostimulation. Methods. Two groups of patients with the «dry» form of age-related macular degeneration were examined. 40 patients (80 eyes) from the main group were treated using combined treatment and 39 patients (78 eyes) in the group of control who were treated conventionally. Results. Before the treatment, decreased blood flow in the internal carotid artery was found in 77.2%, and in the vertebral arteries in 82.2% of patients. Peak amplitude and the stress ratio index at rheoencephalography in the anterior cerebral circulation were 0.83±0.04 Ω and 27.46±0.40%, in the posterior cerebral circulation - 0.70±0.04 Ω and 23.78±0.35%. Peak amplitude values and the stress ratio index have improved significantly right after treatment and after 6 months in the main group compared to the control group. Mean visual acuity in the main group before treatment was 0.87±0.02, right after the treatment - 0.96±0.01 (p <0.001), 2 months after the treatment - 0.95±0.01 (p <0.001), 6 months after the treatment - 0.96±0.01 (p <0.001), 12 months after the treatment - 0.95±0.01 (p <0.001). In the control group mean visual acuity was 0.91±0.02 before the treatment, 0.95±0.02 (p <0.05) - right after the treatment. 2 months after the treatment - 0.94±0.02 (p <0.05), 6 months after the treatment - 0.92±0.02 (p >0.05). 12 months after the treatment mean visual acuity decreased and equaled 0.89±0.02. Decrease of anterior cerebral circulation was found in 77.2% of patients with the «dry» form of age-related macular degeneration, mean peak amplitude value was 0.83±0.04 Ω and the stress ratio index was 27.46±0.40%, decrease of posterior cerebral circulation was found in 82.2% of patients, mean peak amplitude value and the stress ratio index were 0.70±0.04 Ω and 23.78±0.35%. Conclusion. In patients with the «dry» form of age-related macular degeneration posterior cerebral circulation has improved significantly and visual acuity has improved 6 months after combined treatment with polarized polychromatic non-coherent light and dynamic electromyostimulation.

age-related macular degeneration, «dry» form, rheoencephalography, anterior cerebral circulation, posterior cerebral circulation