Pathogenesis and diagnosis of autoimmune oophoritis

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A review of modem literature on problems of etiology, pathogenesis and diagnosis of ovarian autoimmune disorders is presented. Histologic and immunologic diagnostic methods are described. A comparison of our own and literary data allowed to substantiate the existence of normogonadotropic form of autoimmune oophoritis which is not accompanied by primordial follicles disorders and does not lead to the development of hypergonadotropic amenorrhea. This is confirmed by reliable differences in the occurrence of antigens of class IIHLA system in cases of normogonadotropic and hypergonadotropic forms of disease. Attention is attracted to the necessity of early diagnosis while of gonadotropins level is in the limits of physiological fluctuations.

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V. Potin

Ott Research Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences

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俄罗斯联邦, St. Petersburg

E. Smagina

Ott Research Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences

Email: info@eco-vector.com
俄罗斯联邦, St. Petersburg

A. Gzgzian

Ott Research Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences

Email: info@eco-vector.com
俄罗斯联邦, St. Petersburg

V. Rulev

Ott Research Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences

Email: info@eco-vector.com
俄罗斯联邦, St. Petersburg

T. Ioseliani

Ott Research Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences

Email: info@eco-vector.com
俄罗斯联邦, St. Petersburg

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