Systemic Enzyme Therapy during expectant management of preeclampsia: controlled randomised trial

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Systemic Enzyme Therapy (medicine Wobenzym) or standard therapy randomly allocated of pregnant women with mild preeclampsia. Outcome for mothers and fetus, mechanism of action discussed.

作者简介

Margarita Repina

North-Western State Medical University named after I. I. Mechnikov

Email: Margarita.Safronova@szgmu.ru
professor

Tat’yana Korzo

Maternity hospital N 6

Email: Margarita.Safronova@szgmu.ru
physician

参考

  1. Репина М. А., Корзо Т. М., Папаян Л. П., Красовская Г. А, Сумская Г. Ф. Современные подходы к коррекции нарушений гемостаза при беременности, осложненной гестозом. СПб.; 1998
  2. Шитикова А. С., Каргин В. Д., Белязо О. Е. и др. Морфологическая оценка повышенной внутрисосудистой активации тромбоцитов. Методич. реком. СПб.; 1996
  3. Askie L. M., Duley L., Henderson-Smart D. et al. Antiplatelet agents for prevention of preeclampsia: meta-analysis of individual patient data. Lancet. 2007; 369: 1791-8
  4. Dekker G. A., Sibai B. M. Low - dose aspirin in the prevention of preeclampsia and fetal growth retardation. Am. J. Obstet. Gynecol. 1993; 168: 214-7
  5. Duley L., Henderson-Smart D., Knight M., King J. F. Antiplatelet agents for preventing preeclampsia and its complications. Cochrane Database Syst. Rev. 2004: CD 004659
  6. Lockwood C. J., Krikun G., Rahman M. et al. The role of decidualization in regulating endometrial hemostasis during menstrual cycle, gestation and in pathological states. Semin. Thromb. Hemost. 2007; 33: 111-7
  7. Patrono C. Aspirin as an antiplatelet drug. N. Eng. J. Med.1994; 330: 1287-94
  8. Schiff E., Barkai G., Ben-Baruch G., Mashiach S. Low - dose aspirin does not influence the clinical course of women with mild pregnancy induced hypertension. Obstet. Gynecol.1990; 76: 742-4

版权所有 © Repina M.A., Korzo T.M., 2015

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