УРОВЕНЬ НЕСТАБИЛЬНОСТИ МИКРОСАТЕЛЛИТОВ И МУТАЦИИ ГЕНА Р53 В КАРЦИНОМАХ ЖЕЛУДОЧНО-КИШЕЧНОГО ТРАКТА ЧЕЛОВЕКА
- Авторы: Вострюхина О.А.1, Штам Т.А.1, Мохова НВ2, Гуляев А.В.3, Чепик О.Ф.3, Ланцов В.А.1
-
Учреждения:
- Петербургский институт ядерной физики им. Б. П. Константинова, Гатчина, Ленинградская Область, РФ
- Научно-исследовательский институт онкологии им. Н.Н. Петрова, Санкт-Петербург, РФ
- Институт онкологии им. проф. Н.Н. Петрова, Песочный, Ленинградская область, РФ
- Выпуск: Том 2, № 4 (2004)
- Страницы: 22-28
- Раздел: Статьи
- URL: https://journals.rcsi.science/ecolgenet/article/view/5523
- DOI: https://doi.org/10.17816/ecogen2422-28
- ID: 5523
Цитировать
Полный текст
Аннотация
Об авторах
Ольга Альбертовна Вострюхина
Петербургский институт ядерной физики им. Б. П. Константинова, Гатчина, Ленинградская Область, РФ
Email: oavostr@bpc.spbstu.ru
Татьяна Александровна Штам
Петербургский институт ядерной физики им. Б. П. Константинова, Гатчина, Ленинградская Область, РФ
Email: shtam@fromru.com
Н В Мохова
Научно-исследовательский институт онкологии им. Н.Н. Петрова, Санкт-Петербург, РФ
Алексей Викторович Гуляев
Институт онкологии им. проф. Н.Н. Петрова, Песочный, Ленинградская область, РФ
Email: alexandra_kapka@mail.ru
Олег Федорович Чепик
Институт онкологии им. проф. Н.Н. Петрова, Песочный, Ленинградская область, РФ
Email: alexandra_kapka@mail.ru
Владислав Александрович Ланцов
Петербургский институт ядерной физики им. Б. П. Константинова, Гатчина, Ленинградская Область, РФ
Email: dashach066@mail.ru
Список литературы
- Гублер Е.В., Генкин А.А. Применение непараметрических критериев статистики в медико-биологических исследованиях. -Л.: Медицина, 1973
- Boland С, Thibodeau S., Hamilton S. et at. A National cancer institute workshop on microsatellite instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer//Cancer Res. -1998. -Vol. 58. -P. 5248-5257.
- Calm G., Ranzani G., Amadori D. et at. Somatic frameshift mutations in the Bloom syndrome BLM gene are frequent in sporadic gastric carcinomas with microsatellite mutator phenotype//BMC Genet.-2001. -Vbl. 2.-P. 14.
- Chung D., Rustgi A. The hereditary nonpolyposis colorectal cancer syndrome: genetics and clinical implications//Ann. Intern. Med. -2003. -Vol. 138. -P. 560-570.
- Duval A., Hamelin R. Mutations at coding repeat sequences in mismatch repair-deficient human cancer: toward a new concept of target genes for instability//Cancer Res. -2002. -Vol. 62. -P. 2447-2454.
- Elsaleh, Powell В., McCaul K. et al. P53 alteration and microsatellite instability have predictive value for survival benefit from chemotherapy in stage III colorectal carcinoma//Clin. Cancer Res. -2001. -Vol. 7.-P. 1343-1349.
- Fink D., Nebel S., Norris P.S. et al. The affect of different chemotherapeutic agents on the enrichment of DNA mismatch repair-deficient tumour cells//Br. J. Cancer. -1998. -Vol. 77. -P. 703-708.
- Fujiwara Т., Stolker J., Watanabe T. et al. Accumulated clonal genetic alterations in familial and sporadic colorectal carcinomas with widespread instability in microsatellite sequences//Am. J. Pathol. -1998. -Vol. 153. -P. 1063-1078.
- Goelz S., Hamilton S., Vogelstein B. Purification of DNA from formaldehyde fixed and paraffin embedded human tissue//Biochem. Biophys. Res. Commun. -1985. -Vol. 130. -P. 118-126.
- Ilyas M., Tomlinson I.P.M. Genetic pathways in colorectal cancer//Histopathology. -1996. -Vol. 28. -P. 389-399.
- Jass J.R., Biden K.G., Cummings M.C. et al. Characterization of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways//J. Clin. Pathol. -1999. -Vol. 52. -P. 455-460.
- Kim J., Baek M., Kim L. et al. Accumulated frameshift mutations at coding nucleotide repeats during the progression of gastric carcinoma with microsatellite instability//Lab. Invest. -1999. -Vol. 79. -P.1113-1120.
- Loukola A., Eklin K, Laiho P. et al. Microsatellite marker analysis in screening for hereditary nonpolyposis colorectal cancer (HNPCC)//Cancer Res. -2001. -Vol. 61. -P. 4545-4549.
- Manic S., Gatti L., Carenini N. et al. Mechanisms controlling sensivity to platinum complexes: p53 and DNA mismatch repair//Curr. Cancer Drug Targets. -2003. -Vol. 3. -P. 21-29.
- Olivier M., Eeles R., Hollstein M. et al. The IARC TP53 Database: new online mutation analysis and recommendations to users//Hum. Mutat. -2002. -Vol. 19. -P. 607-614.
- Peltomaki P. Deficient DNA mismatch repair: a common etiology factor for colon cancer//Hum Mol Genetics. -2001. -Vol. 10. -P. 735-740.
- Pestell K., Hobbs S., Titley J. et al. Effect of p53 status on sensivity to platinum complexes ir^a human ovarian cancer cell line//Molecular Pharmacol. -2000. -Vol. 57. -P. 503-509.
- Redston M. Carcinogenesis in the GI tract: from morphology to genetics and back again//Mod. Pathol. -2001. -Vol. 14. -P. 236-245.
- Salahshor S., Kressner U., Glimelius B. et al. Colorectal cancer with and without microsatellite instability involves different genes//Genes Chromosomes Cancer. -1999. -Vol. 26. -P. 247-252.
- Samowitz W., Holden/., Curtin K.et al. Inverse relationship between microsatellite instability and k-ras and p53 gene alterations in colon cancer//Am. J. Pathol. -2001, -Vol. 158.-P. 1517-1524.
- Samowitz W.S., Slattery M.L., Potter J.D. et al. BAT-26 and BAT-40 Instability in Colorectal Adenomas and Carcinomas and Germline Polymorphism//Am. J. Pathol. -1999. -Vol. 154. -P. 1637-1641.
- Steingrimsdottir H., Penhallow J., Farzaneh F. et al. Detection of p53 mutations in oral cancer samples using a sensitive PCR-based method//Biochem. Soc. Trans. -1997. -Vol. 25. -P. 315-318.
- Umar A., Boland C.R., Terdiman J.P. et al. Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability//J. Natl. Cancer Inst. -2004. -Vol. 96. -P. 261-268.
- Ward R., Meagher A., Tomlinson I. et al. Microsatellite instability and the clinicopathological features of sporadic colorectal cancer//Gut. -2001. -Vol. 48. -P. 821-829.
- Yamamoto H., Itoh F., Fukushima H. et al. Frequent Bax frameshift mutations in gastric cancer with high but not low microsatellite instability//J. Exp. Clin. Cancer Res. -1999. -Vol. 18. -P. 103-106.
- Yan Т., Berry S.E., Desai А.В., Kinsella T.J. DNA mismatch repair (MMR) mediates 6-thioguanine genotoxicity by introducing single-strand breaks to signal a G2-M arrest in MMR-proficient RKO cells//Clin. Cancer. Res. -2003. -Vol. 9. -P. 2327-2334.
- Yoshitaka Т., Matsubara N., Ikeda M. et al. Mutations of E2F4 trinucleotide repeats in colorectal cancer with microsatellite instability//Biochem. Biophys. Res. Commun. -1996. -Vol. 227. -P. 553-557.
- Young J., Simms L., Biden К et al. Features of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic setting//Am, J. Pathol. -2001. -Vol. 159. -P. 2107-2116