Surgical Treatment of Stage I and II Thymus Epithelial Tumors

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Abstract

Thymic epithelial tumors are the most common tumors of the anterior mediastinum, with an incidence of 0.18 per 100,000 population. Here, we present a review of the national and foreign literature on the surgical treatment of stage I and II thymic epithelial tumors. The Medline (PubMed) and Russian Science Citation Index (eLibrary) databases were used as search engines. The focus of the review is the problem of choosing the optimal minimally invasive surgical approach for thymectomy, and the need for lymph node dissection for thymic epithelial tumors. A number of issues remain currently unresolved in thymic epithelial tumors surgery, namely the justification of the preoperative histological verification of the tumor process, the choice of the optimal surgical access to the anterior mediastinum, the need for and prognostic effect of lymph node dissection, and the determination of the required volume of the planned operation.

About the authors

Evgeny A. Epifantsev

Federal Research and Clinical Center of Specialized Medical Care and Medical Technologies

Author for correspondence.
Email: epifantsev.e@gmail.com
ORCID iD: 0000-0001-9768-7440
SPIN-code: 1820-2153
Russian Federation, Moscow

Vladimir Yu. Gritsun

Federal Research and Clinical Center of Specialized Medical Care and Medical Technologies

Email: ords1313@gmail.com
ORCID iD: 0000-0001-7647-9853
Russian Federation, Moscow

Aishe A. Keshvedinova

Federal Research and Clinical Center of Specialized Medical Care and Medical Technologies

Email: aishe1998@mail.ru
ORCID iD: 0000-0002-0045-2715
SPIN-code: 1577-0901
Russian Federation, Moscow

Alexander V. Smirnov

Federal Research and Clinical Center of Specialized Medical Care and Medical Technologies

Email: alvsmirnov@mail.ru
ORCID iD: 0000-0003-3897-8306
SPIN-code: 5619-1151

MD, PhD

Russian Federation, Moscow

Yury V. Ivanov

Federal Research and Clinical Center of Specialized Medical Care and Medical Technologies; Central Research Institute of Tuberculosis

Email: ivanovkb83@yandex.ru
ORCID iD: 0000-0001-6209-4194
SPIN-code: 3240-4335

MD, PhD, Dr. Sci. (Med.), Professor

Russian Federation, Moscow; Moscow

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