Email this article Multifaces of hypertrophic cardiomyopathy: a case of transformation of hypertrophic phenotype into dilated
- Authors: Novikova T.N.1, Andreeva A.E.1, Bitakova F.I.1, Novikov V.I.1, Gladysheva K.A.1, Petrova P.V.1, Stalnova P.A.1, Tokareva N.A.1
-
Affiliations:
- North-Western State Medical University named after I.I. Mechnikov
- Issue: Vol 4, No 1 (2024)
- Pages: 31-41
- Section: Case reports
- URL: https://journals.rcsi.science/cardar/article/view/257370
- DOI: https://doi.org/10.17816/cardar630134
- ID: 257370
Cite item
Abstract
The article presents a clinical case of a rather rare course of hypertrophic cardiomyopathy with the transformation of a hypertrophic phenotype into a dilated phenotype against the background of the “burned-out phase” phenomenon, ventricular and supraventricular rhythm disturbances, and multiple genetic mutations. Timely started disease-modifying therapy (quadruple therapy) for chronic heart failure led to reverse positive remodeling of the left chambers of the heart.
Full Text
##article.viewOnOriginalSite##About the authors
Tatiana N. Novikova
North-Western State Medical University named after I.I. Mechnikov
Author for correspondence.
Email: novikova-tn@mail.ru
ORCID iD: 0000-0003-4655-0297
SPIN-code: 3401-0329
MD, Cand. Sci. (Med.), Assistant Professor of the Department of Hospital Therapy and Cardiology named after M.S. Kushakovskiy
Russian Federation, Saint PetersburgAlina E. Andreeva
North-Western State Medical University named after I.I. Mechnikov
Email: Doc.alina@mail.ru
ORCID iD: 0009-0004-1212-5406
SPIN-code: 7378-1194
Head of hospital department of functional diagnostics, Assistant Professor
Russian Federation, Saint PetersburgFatima I. Bitakova
North-Western State Medical University named after I.I. Mechnikov
Email: Fatima.Bitakova@szgmu.ru
ORCID iD: 0000-0001-6637-8266
SPIN-code: 8624-7193
MD, Cand. Sci. (Med.), Assistant Professor
Russian Federation, Saint PetersburgVladimir I. Novikov
North-Western State Medical University named after I.I. Mechnikov
Email: novikov-vi@mail.ru
ORCID iD: 0000-0002-2493-6300
SPIN-code: 6909-3377
MD, Dr Sci. (Med.), Professor
Russian Federation, Saint PetersburgKristina A. Gladysheva
North-Western State Medical University named after I.I. Mechnikov
Email: kirklandgladysheva@mail.ru
ORCID iD: 0009-0001-2262-2770
6th year student
Russian Federation, Saint PetersburgPolina V. Petrova
North-Western State Medical University named after I.I. Mechnikov
Email: apolly2017@yandex.ru
ORCID iD: 0000-0002-2658-9920
clinical resident
Russian Federation, Saint PetersburgPolina A. Stalnova
North-Western State Medical University named after I.I. Mechnikov
Email: polya161001@gmail.com
ORCID iD: 0009-0009-5835-8359
6th year student
Russian Federation, Saint PetersburgNadezhda A. Tokareva
North-Western State Medical University named after I.I. Mechnikov
Email: tokareva.nad9@mail.ru
ORCID iD: 0009-0001-2663-5640
clinical resident
Russian Federation, Saint PetersburgReferences
- Arbelo E, Protonotarios A, Gimeno JR, et al. 2023 ESC Guidelines for the management of cardiomyopathies. Eur Heart J. 2023;44(37):3503–3626. doi: 10.1093/eurheartj/ehad194
- Raphael CE, Cooper R, Parker KH, et al. 2016 Mechanisms of myocardial ischemia in hypertrophic cardiomyopathy: insights from wave intensity analysis and magnetic resonance. J Am Coll Cardiol. 2016;68(15):1651–1660. doi: 10.1016/j.jacc.2016.07.751
- Novikov VI, Novikova TN. Cardiomyopathies. 2nd ed., rev. and supplement. Moscow: MEDpress-Inform; 2024. 144 p. (In Russ.)
- Brinkley DM, Wells OS, Stevenson LW. Avoiding burnout from hypertrophic cardiomyopathy. J Am Coll Cardiol. 2020;75(24): 3044–3047. doi: 10.1016/j.jacc.2020.05.009
- Potter E, Marwick TH. Assessment of left ventricular function by echocardiography: the case for routinely adding global longitudinal strain to ejection fraction. JACC Cardiovasc Imaging. 2018;11(2(Pt 1)):260–274. doi: 10.1016/j.jcmg.2017.11.017
- Pathan F, D’Elia N, Nolan MT, et al. Normal ranges of left atrial strain by speckle-tracking echocardiography: a systematic review and meta-analysis. J Am Soc Echocardiogr. 2017;30(1):59–70.e8. doi: 10.1016/j.echo.2016.09.007
- McDonagh TA, Metra M, Adamo M, et al. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: Developed by the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) With the special contribution of the Heart Failure Association (HFA) of the ESC. Euro Heart J. 2021;42(36):3599–3726. doi: 10.1093/eurheartj/ehab368
- Tereshchenko SN, Galyavich AS, Uskach TM, et al. 2020 Clinical practice guidelines for Chronic heart failure. Russian Journal of Cardiology. 2020;25(11):311–374. EDN: LJGGQV doi: 10.15829/1560-4071-2020-4083
- Gabrusenko SA, Gudkova AYa, Koziolova NA, et al. 2020 Clinical practice guidelines for Hypertrophic cardiomyopathy. Russian Journal of Cardiology. 2021;26(5):269–334. EDN: MXDYLE doi: 10.15829/1560-4071-2021-4541
- Adamczak DM, Rogala A, Antoniak M, Oko-Sarnowska Z. New predictors of burned-out phase in hypertrophic cardiomyopathy. Eur Heart J Cardiovasc Imaging. 2020;21(Supplement_1). doi: 10.1093/ehjci/jez319.828
- Zeppenfeld K, Tfelt-Hansen J, de Riva M, et al. 2022 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. Eur Heart J. 2022;43(40):3997–4126. doi: 10.1093/eurheartj/ehac262
- Novikova TN, Bitakova FI, Ignatieva VS, et al. European guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death 2022: cardiomyopathy. What’s new? Cardiac Arrhythmias. 2023;3(3):41–62. EDN: DHKBZF doi: 10.17816/cardar56
Supplementary files
