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Том 6, № 1 (2016)
- Год: 2016
- Статей: 3
- URL: https://journals.rcsi.science/2634-8276/issue/view/13562
Article
Determination of cholesterol in blood. Part 1
Аннотация
The chronological development of procedures for determining the concentration of cholesterol in plasma, serum, and whole blood is presented in the review. It is stated that, since the correlation between the risk of development of cardiovascular diseases and the concentrations of total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol in human blood was established by numerous medical studies, the procedures for the measurement of these parameters have been developed most actively. A brief overview of these procedures and the results of their comparative tests in medical examination of patients are given. The classifications of the procedures for determining total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol in blood are also proposed. The mechanism of action of the chemical reactions taking place in these procedures, the advantages and disadvantages, and the priority field of their application are considered. The promising directions of development and improvement of procedures are mentioned, ensuring more accurate measurements of the concentration of cholesterol in blood, and alternative ways of determining the risk of cardiovascular disease are discussed.
1-48
Copper-containing enzymes: Site types and low-molecular-weight model compounds
Аннотация
A structured description is suggested for the existing types of copper-containing sites in copper proteins. The most important specific features of mono-, di-, tri-, and tetranuclear sites are reported, and the structural geometry of each site is considered. The functional features and catalytic reactions characteristics of each type of site are discussed. Examples of copper-containing enzyme mimics are considered, and the importance of their synthesis and use is demonstrated.
49-82
Technologies for the synthesis of ethylene and propylene from natural gas
Аннотация
Different technologies for the synthesis of ethylene and propylene from natural gas are considered. The simplest ethylene synthesis method is the oxidative condensation (or dimerization) of methane (OCM process), but the implementation of this method is discouraged by a low ethylene yield. Among the relatively simple methods for the synthesis of ethylene (together with acetylene) immediately from methane are thermooxidative pyrolysis (TOP process) and pyrolysis in the presence of chlorine (Benson process), whose disadvantages are a high temperature and a great number of by-products. A wide range of processes for the synthesis of ethylene and propylene with a small amount of butylenes are based on the intermediate synthesis of syngas from methane and its further use for the direct synthesis of lower olefins or products for subsequent catalytic pyrolysis to lower olefins, such as methanol (methanol-to-olefins (MTO) and methanol-to-propylene (MTP) processes), dimethyl ether, and liquid fuel (Fischer–Tropsch method). The methyl chloride-to-olefins (MCTO) process consisting of the synthesis of methyl chloride via the oxidative chlorination of methane and the catalytic pyrolysis of methyl chloride differ from these three-stage processes in the absence of the syngas production stage. The direct oxidation of methane to methanol and the homologyzation of methanol to ethanol with further dehydration of ethanol to ethylene are also considered.
83-123