MEMBERS OF THE FAMILY LAMIACEAE LINDL. AS SOURCES OF MEDICINAL PLANT RAW MATERIALS TO OBTAIN NEUROTROPIC DRUGS


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The aim of this work is to review and analyze the data published in the modern scientific literature obtained in pharmacological, pharmacognostic and pharmacotechnological studies of various types of raw materials obtained from members of the family Lamiaceae L., which were sources of biologically active substances, pharmaceutical substances, total extracts and the drugs – with a neurotropic activity.

Materials and methods. For the review, we used the information of scientific literature from open and accessible sources of the last twenty years, located in the scientific and technical libraries of institutions, as well as in electronic databases: Elibrary, PubMed, Scopus, Cyberleninka, GoogleAcademy, J-Stage. The search inquiries were: the species of the family Lamiaceae (Russian and Latin), the samples of medicinal plant materials based on them as well as the names of the drugs and biologically active substances obtained from these raw materials.

Results. When working with the sources of scientific information, the main attention was paid to pharmacologic tests performed during the studies on laboratory animals and proving the presence of neurotropic activity in the studied objects – essential oils and extracts from plant raw materials: aqueous, aqueous alcoholic, and methanol ones. It has been established that the potential of the therapeutic and preventive application of pharmaceutical substances and drugs based on the medicinal plant materials obtained from 30 genera members of the Lamiaceae family, remains unrealized despite the close attention of various researchers.

Conclusion. This review comprised 71 species from 30 genera. Despite the significant level of the previous study presented in the analysis of this publication, an enormous potential of this family’s species remains unexplored. In the future, they can be of both – pharmacognostic and practical interest, in particular, in creation of new medicinal preparations of the neurotropic action based on them.

作者简介

Ekaterina Zvezdina

All-Russia Scientific Research Institute of Medicinal and Aromatic Plants

Email: catterina@inbox.ru
ORCID iD: 0000-0001-5708-3407

Post-graduate Student, Senior Researcher of the Department of Phytochemistry and Standardization, All Russia Scientific Research Institute of Medicinal and Aromatic Plants

俄罗斯联邦, Moscow

Zhanna Dayronas

Pyatigorsk Medical and Pharmaceutical Institute – a branch of Volgograd State Medical University

Email: daironas@mail.ru
ORCID iD: 0000-0002-1274-4512

Doctor of Sciences (Pharmacy), Professor, Head of the Department of Pharmacognosy, Botany and Technology of Phytopreparations. Pyati- gorsk Medical and Pharmaceutical Institute - a branch of Volgograd State Medical University.

俄罗斯联邦, Pyatigorsk

Inna Bochkareva

Maykop State Technological University

Email: bochkarevainna@gmail.com

Candidate of Sciences (Pharmacy), Associate Professor, Head of the Department of Pharmacy, Maykop State Technological University.

俄罗斯联邦, Maykop

Ifrat Zilfikarov

All-Russia Scientific Research Institute of Medicinal and Aromatic Plants; Maykop State Technological University

Email: dagfarm@mail.ru
ORCID iD: 0000-0002-8638-9963

Doctor of Sciences (Pharmacy), Professor of RAS, Chief Researcher, Department of Phytochemistry and Standardization, All-Russian Scientific Research Institute of Medicinal and Aromatic Plants.

俄罗斯联邦, Moscow; Maykop

Elena Babaeva

All-Russia Scientific Research Institute of Medicinal and Aromatic Plants

Email: babaevaelena@mail.ru
ORCID iD: 0000-0002-4992-6926
SPIN 代码: 4230-0443

Candidate of Sciences (Biology), Senior Research Officer, All Russia Research and Development Institute of Medicinal and Aromatic Plants.

俄罗斯联邦, Moscow

Ekaterina Ferubko

All-Russia Scientific Research Institute of Medicinal and Aromatic Plants

Email: eferubko@yandex.ru

Candidate of Sciences (Medicine) Head of the Department of Experimental and Clinical Pharmacology, All-Russian Research Institute of Medicinal and Aromatic Plants.

俄罗斯联邦, Moscow

Ziyarat Guseynova

Federal State Institution of Science Dagestan Scientific Center of Russian Academy of Sciences

Email: guseinovaz@mail.ru
ORCID iD: 0000-0003-0355-4132

Candidate of Sciences (Biology), Senior Researcher, Laboratory of Flora and Plant Resources, Mountain Botanical Garden, Dagestan Federal Research Center, Russian Academy of Sciences.

俄罗斯联邦, Makhachkala

F. Serebryanaya

Pyatigorsk Medical and Pharmaceutical Institute – a branch of Volgograd State Medical University

Email: f.k.serebryanaya@pmedpharm.ru
ORCID iD: 0000-0001-9409-9344

Candidate of Sciences (Pharmacy), Associate Professor of the Department of Pharmacognosy, Botany and Technology of Phytopreparations. Pyatigorsk Medical and Pharmaceutical Institute – a branch of Volgograd State Medical University. Researcher of the Ecological and Botanical Station of the BIN RAS (Perkalsky Denrological Park).

俄罗斯联邦, Pyatigorsk

Sabina Kaibova

Dagestan State Medical University

Email: kaibova.00@mail.ru
ORCID iD: 0000-0003-2773-6387

Candidate of Sciences (Pharmacy), Associate Professor, Department of Pharmacy, Dagestan State Medical University.

俄罗斯联邦, Makhachkala

Timur Ibragimov

Dagestan State Medical University; Dagestan State University

编辑信件的主要联系方式.
Email: aloefarm@mail.ru
ORCID iD: 0000-0001-9809-1120

Candidate of Sciences (Pharmacy), Associate Professor, Department of Analytical and Pharmaceutical Chemistry, Dagestan State University.

俄罗斯联邦, Makhachkala; Makhachkala

参考

  1. Kryzhanovsky GN, Magaeva SV, Makarov SV. Neuropatologiya [Neuroimunopathology]. M.: Medicina; 1997. 282 p. Russian
  2. Selye G. Ocherki o adaptsionnom syndrome [Essays on Adaptation Syndrome]. Per. s ang. Candrora VI i Rogova AA. M.: Medgiz.; 1969. 253 p. Russian
  3. Alyautdin RN, Huseynov MD, Zilfikarov IN, Romanov BK. Stress-protectornaya phytoterapiya [Stress-protektor medicine]. Biomedicine. 2011;3:115–9. Russian
  4. Vsemirnaya organizatsiya zdravoohraneniya. Profilaktika serdechno-sosudistykh zabolevanii [World Health Organization. Cardiovascular Disease Prevention]. Karmannoe posobie po otsenke i snizheniyu riska serdechno-sosudistykh zabolevanii. Geneva; 2007. 22 p. Russian
  5. Gosudarstvennyi reestr lekarstvennyh sredstv [The state register of medicines]. [cited 2019 Dec 16]. Available from: http://grls.rosminzdrav.ru/grls.aspx Russian
  6. Kukes VG, Bulaev VM, Kolkhir VK. Metodicheskie ukazaniya po doclinicheskomu izucheniyu novyh preparatov, razrabatyvaemyh iz prirodnogo syrya [Guidelines for the preclinical study of new drugs developed from natural raw materials]. Rukovodstvo po experimentalnomu (doklinicheskomu) izucheniyu novyh pharmakologicheskih veshchestv. M. 2000; 346–8. Russian
  7. Rukovodstvo po provedeniyu doklinicheskih issledovanii lekarstvennyh sredstv [Guidelines for preclinical studies of drugs]. Ch. 1. Pod. red. Mironova АN. M.: Grif i K; 2013. 944 p. Russian
  8. Rukovodstvo po experimentalnomu (doklinicheskomu) uzycheniyu novyh pharmacologicheskih veshchestv [Guidance on the experimental (preclinical) study of new pharmacological substances]. Pod. red. Habrieva PU. 2-e izd. pererab. I dop. M.: OAO Izd-vo «Medicina»; 2015. 832 p. Russian
  9. Bakhtiyarova ShK, Kapysheva UN, Ablaykhanova NT, Ablaykhanova NT, Baimbetova AK, Zhaksymov BI, Korganbaeva AA, Ydyrys A, Bolatkhan MB, Dautova MB. Povedeniya zhivotnyh v razlichnyh testah. [Behavior of animals in various tests]. International Journal of applied and fundamental research. 2017;8:92–6. Russain
  10. Zupanets IA, Bezdetko NV. Pharmacevticheskaya opeka: simptomaticheskoe lechenie trevozhnyh sostoyanii [Pharmaceutical custody: symptomatic treatment of anxiety]. Provizor. 2002; 24:35. Russian
  11. Tarakhovsky YuS, Kim YuA, Abdrasilov BS, Muzafarov EN. Flavonoidi: biochimiya, biofizika, medicina [Flavonoids: biochemistry, biophysics, medicine]. Pushchino: Sуnchrobook; 2013. 310 p. Russian
  12. Pereira P, de Oliveira PA, Ardenghi P, Rotta L, Henriques JA, Picada JN. Neuropharmacological Analysis of Caffeic Acid in Rats. Basic and Clinical Pharmacology and Toxicology. 2006; 99: 374–8.
  13. Lallement-Guilbert N, Bézanger-Beauquesne L. Recherches sur les flavonoides quelques Labiees médicinales (romarin, menthe poivrée, suage officinale). Plantes Médicinales et Phytothérapie. 1970; 4:92–107.
  14. Pereira P, Tysca D, Oliveira P, da Silva LF, Brum LF, Picada JN, Ardenghi P. Neurobehavioral and genotoxic aspects of rosmarinic acid. Pharmacological Research. 2005; 52(3): 199–203.
  15. Gurgel do Vale T, Couto Furtado E, Jr Santos JG, Viana GSB. Central effects of citral, myrcene and limonene, constituents of essential oil chemotypes from Lippia alba. Phytomedicine. 2002; 9(8): 709–14.
  16. Gomes PB, Feitosa ML, Silva MI, Noronha EC, Moura BA, Venâncio ET, Rios ER, de Sousa DP, de Vasconcelos SM, Fonteles MM, de Sousa FC. Anxiolytic-like effect of the monoterpene 1,4-cineole in mice. Pharmacol Biochem Behav. 2010; 96(3): 287–93.
  17. The Plant List (2013). [cited 2019 Dec 16]. Version 1.1. Available from: http://www.theplantlist.org
  18. Flora SSSR [Flora of the USSR]. Red. Shishkin BK. M.–L.: Izd-vo AN SSSR.1954; 20:556 p. Russian
  19. Fuentes-Granados R, Widrlechner MP, Wilson LA. An overview of Agastache research. Journal of Herbs, Spices & Medicinal Plants. 1998; 6(1): 69–97.
  20. Estrada-Reyes R, López-Rubalcava C, Ferreyra-Cruz OA, Dorantes-Barrón AM, Heinze G, Moreno Aguilar J, Martínez-Vázquez M. Central nervous system effects and chemical composition of two subspecies of Agastache mexicana; an ethnomedicine of Mexico. Journal of Ethnopharmacology. 2014; 153 (1): 98–110.
  21. Molina-Hernandez M, Tellez-Alcantara P, Martinez E. Agastache mexicana may produce anxiogenic-like actions in the male rat. Phytomedicine. 2000; 7 (3):199–203.
  22. Zielińska S, Matkowski A. Phytochemistry and bioactivity of aromatic and medicinal plants from the genus Agastache (Lamiaceae). Phytochemistry Reviews. 2014; 13: 391–416.
  23. Luvah GM, Ochieng CO, Ishola IO, Manguro LOA, Owuor PO. Anxiolytic-Like Effect of Underground Parts of Ajuga remota Benth (Lamiaceae) and Its Bioactive Constituents in Mice: A Behavioral Study. The Natural Products Journal. 2014; 4(3): 211–6.
  24. Uddin MJ, Ali Reza ASM, Abdullah-Al-Mamun M, Kabir MSH, Nasrin MS, Akhter S, Arman MSI, Rahman MA. Antinociceptive and Anxiolytic and Sedative Effects of Methanol Extract of Anisomeles indica: An Experimental Assessment in Mice and Computer Aided Models. Front Pharmacol. 2018; 9: 246.
  25. Citoglu G, Tanker M, Sever B, Englert J, Anton R, Altanlar N. Antibacterial activities of diterpenoids isolated from Ballota saxatilis subsp. saxatilis. PlantaMed. 1998; 64: 484–5.
  26. Kruglaya AA. Phenolnye soedineniya travi bellokudrennika chernogo (Ballota nigra L.), proizrastayuschego na Severnom Kavkaze [Phenolic compounds of black horehound (Ballota nigra L.) which crows in the North Caucasus. Nauchnye vedomosti Belgorodskogo gosudarsnvennogo universiteta. Seria: Medicina. Pharmaciya. 2013; 21; 4(147):226–8. Russian
  27. Yanitskaya AV, Mitrofanova IYu. Sostav I soderzhanie phenolnyh soedinenii v nadzemnoi chasti bellokudrennika chernogo, proizrastayucshego v Volgogradskoi oblasti. [The structure and content compounds in overground part Ballota nigra growing in Volgograd region]. Vestnik Volgogradskogo gosudarstvennogo medicinskogo universiteta. 2013; 4 (48): 70–1. Russian
  28. Daels-Rakotoarison DA, Seidel V, Gressier B, Brunet C, Tillequin F, Bailleul F, Luyckx M, Dine T, Cazin M, Cazin JC. Neurosedative and antioxidant activities of phenylpropanoids from Ballota nigra. Arzneimittelforschun. 2000; 50 (1): 16–23.
  29. Citoglu G, Tanker M, Sever B. Note Flavonoid Aglycones from Ballota saxatilis subsp. saxatilis. Pharmaceutical biology. 1999; 37(2): 158–60.
  30. European Pharmacopoeia, 8th edition (Ph. Eur. 2013). Strasbourg (FR): Directorate for the Quality of Medicines and Health Care of the Council of Europe (EDQM). 2013: 1185–6.
  31. Pieretti S, Di Giannuario A, Capasso A, Nicoletti M. Pharmacological effects of phenylpropanoid glycosides from Orobanchehederae. Phytother Res. 1992; 6 (2): 89–93.
  32. Vural K, Ezer N, Erol K, Sahin FP. Anxiolytic and antidepressant activites of some Ballota species. J. Pharm. Gazi. 1996; 13 (1): 29–32.
  33. Bertrand MC, Tillequin F, Bailleul F. Two major flavonoids from Ballota nigra. Biochemical Systematics and Ecology. 2000; 28: 1031–3.
  34. Vrchovska V, Spilkova J, Valentao P, Sousa C, Andrade PB, Seabra RM. Antioxidative properties and phytochemical composition of Ballota nigra infusion. Food Chemistry. 2007; 105: 1396–403.
  35. Chaudhary MA, Ahmed D, Khan SR. A Study of Ballota limbata as an Alternative Medicine for Eye Diseases. Ethnobotanical Leaflets. 2009; 13: 1088–95.
  36. Vazhayil BK, Rajagopal SS, Thangavelu T, Swaminathan G, Rajagounder E. Neuroprotective effect of Clerodendrum serratum Linn. leaves extract against acute restraint stress-induced depressive-like behavioral symptoms in adult mice. Indian J Pharmacol. 2017; 49 (1): 34–41.
  37. Cassani J, Escalona GAA, Martínez-Vázquez M, Manjarrez N, Moreno J, Estrada-Reyes R. Anxiolytic-Like and Antinociceptive Effects of 2(S)-Neoponcirin in Mice. Molecules. 2013; 18: 7584–99.
  38. Wu ZY, Li XW. Flora reipublicae popuplaris sinicae (Zhongguo Zhiwu Zhi). Beijing Science Press. 1977;65 p.
  39. Popova OI, Nikitina AS. Zmeegolovnik moldavskii i issop lekarstvennyi: sovrmennyi vzglyad na rasteniya [Moldavian snakehead and hyssop officinalis: a modern look at plants]. Volgograd: Izdatelstvo VolgGMU. 2014; 224 p. Russian
  40. Martínez-Vàzquez M, Estrada-Reyes R, Martínez-Laurrabaquio A, López-Rubalcava C, Heinze G. Neuropharmacological study of Dracocephalum moldavica L. (Lamiaceae) in mice: Sedative effect and chemical analysis of an aqueous extract. Journal of Ethnopharmacology. 2012; 141: 908–17.
  41. Nisar M, Khan S, Dar A, Rehman W, Khan R, Jan I. Antidepressant screening and flavonoids isolation from Eremostachys laciniata (L) Bunge. African Journal of Biotechnology. 2011; 10 (9): 1696–9.
  42. Ngo Bum E, Taiwe GS, Nkainsa LA, Moto FCO, Seke Etet PF, Hiana IR, Bailabar T, Rouyatou Papa Seyni, Rakotonirina A, Rakotonirina SV. Validation of anticonvulsant and sedative activity of six medicinal plants. Epilepsy & Behavior. 2009; 14: 454–8.
  43. Rastitelnye resursy Rossii: Dikorastuschie Tsvetkovye rasteniya, ih komponentnyi sostav i biologicheskaya aktivnost [Plant resources of Russia: Wild flowering plants, their component composition and biological activity]. SPb.: Tovarischestvo nauchnyh izdanii КМК. 2011;4:630. Russian
  44. Karomatov ID, Zhumaeva HH. Lagohilus opyanyayuschii. [Lagokhilus intoxicating]. Biologiya i interactivnnaya medicina. 2017; 1: 277–82. Russian
  45. Vedmedeva EV, Tarasova YA, Lebed ZI. Izuchenie kollektsii lyallemantsii instituta maslinichnyh kultur. [Studying lallemantia collection at the institute of oilseed crops]. Naukovo-technichnii buyleten Institutu oliinih kultur HAAN. 2010; 15: 39–44. Ukrain
  46. Hyder N, Musharraf SG, Shyum Naqvi SB. Diazepam-Like Effects of Lallemantia royleana Benth. (Lamiaceae) seeds in anxiety disorder. Journal of the Neurological Sciences. 2017; 381: 561–756.
  47. Manyshkina TN, Вygayenko LA. Sposoby razmnozheniya lavandy (Lavandula angustifolia Mill.) [Lavender propagation methods (Lavandula angustifolia Mill.)]. Nauchnyi zhurnal KubGAU. 2015; 108(04): 2–11. Russian
  48. Prusinowska R, Smigielski KB. Composition, biological properties and therapeutic effects of lavender (Lavandula angustifolia L.). A review. Herba Polonica. 2014; 60(2): 56–66.
  49. Rabiei Z, Rabiei S. A review on antidepressant effect of medicinal plants. Bangladesh J Pharmacol. 2017; 12: 1–11.
  50. Lamrini M, Kurkin VA, Mizina PG, Belyaeva MV, Arutyunov YuI, Onuchak LA. Flavonoidy i terpenoidy tsvetkov lavandy kolosovoi [Flavonoids and terpenoids of spikelet lavender flowers]. Chimiya rastitelnogo syrya. 2018; 1: 77–80. Russian
  51. Lamrini M, Kurkin VA, Mizina PG, Belyaeva MV, Arutyunov YuI, Onuchak LA. Flavonoidy I ephirnoe maslo tsvetkov lavandy kolosovoi. [Lavender (Lavandula spica) flower flavonoids and essential oil]. Pharmacy. 2008; 1:16–9. Russian
  52. Kurkin VA, Lamrini M, Klochkov SG. Lavandoside from Lavandula spica flowers. Chemistry of Natural Compounds. 2008; 44(2): 169–70.
  53. Gilani AH, Aziz N, Khan MA, Shaheen F, Jabeen Q, Siddiqui BS, Herzig JW. Ethnopharmacological evaluation of the anticonvulsant, sedative and antispasmodic activities of Lavandula stoechas L. Journal of Ethnopharmacology. 2000; 71 (1–2): 161–7.
  54. Ayanwuyi LO, Kwanashie HO, Hussaini IM, Yaro AH. Preliminary studies on the behavioural effects of the methanol extract of Leonotis nepetifolia Linn stem in mice. Afr J Tradit Complement Altern Med. 2016; 13(4): 15–21.
  55. Cherepanov SK. Sosudistye rastenia Rossii i sopredelnyh gosudarstv (v predelah byvshego SSSR) [Vascular plants of Russia and neighboring states (within the former USSR)]. SPb.; 1995. 989 p. Russian
  56. Danilov SA, Shtrygol SYu, Stepanova SI. Pustyrnik: phitohimicheskie ossobennosti i novye grani farmakologicheskih svoistv [Motherwort: phytochemical characteristics and new facets of pharmacological properties]. Provisor. 2011; 9: 27–30. Russian
  57. Evdokimova NI, Pulatova TP, Isamuhamedova GP. Iridoidy semeistva yasnotkovyh kak farmakologicheski aktivnye veschestva [Iridoids of plants of the family Lamiaceae as pharmacologically active substances]. Org. i econ. farmatsii, technol. i farmacol. nekotor. lekarstv. preperatov. Sb. nauch. tr. Tashkent: Tashk. gos. med. in-t. 1990; 50–3. Russian
  58. Makarov VG, Aleksandrova AE, Shikov AN, Chiler LV, Ryzhenkov VE. Experimentalnoe i klinicheskoe izuchenie vliyania preparata iridol na tsentralnuyu nervnuyu sistemu [Experimental and clinical study of preparation iridol action on the central nervos system]. Experimental and Clinical Pharmacology.2006;69(3):23–5. Russian
  59. Serebryannaya FK. Ecologo-botanicheskie i phytohimicheskie issledovaniya predstavitelei semeistva Lamiaceae v ramkah provedeniya komplexnogo monitoring perspectivnyh resursnyh vidov flory Severnogo Kavkaza. [Ecological, botanical and phytochemical investigations of the representants of the Lamiaceae family in the connection with monitoring of resource species from Northern Caucasus flora]. Flora i zapovednoe delo na Kavkaze: istoriya i sovremennoe sostoyanie izuchennosti: materialy mezhdunarodnoi konferentsii (22–25 maya g. Pyatigorsk). Pyatigorsk; 2019: 76–84. Russian
  60. Dathaev UM, Kapsalyamova EN, Yeleuova EI, Orazbekov EK. Nalichie sedativnogo svoistva LR pustyrnik. [Pustyrnik. Sedative property existence]. Vestnik Kazahskogo Natsionalnogo medicinskogo universiteta. 2014; 1: 339–41. Russian
  61. Rauwald HW, Savtschenko A, Merten A, Rusch C, Appel K, Kuchta K. GABAA Receptor Binding Assays of Standardized Leonurus cardiaca and Leonurus japonicus Extracts as Well as Their Isolated Constituents. Planta Med. 2015; 81 (12/13): 1103–10.
  62. Zhang R-H, Liu Z-K, Yang D-S, Zhang X-J, Sun H-D, Xiao W-L. Phytochemistry and pharmacology of the genus Leonurus: The herb to benefit the mothers and more. Phytochemistry. 2018; 147: 167–83.
  63. Wojtyniak K, Szymański M, Matławska I. Leonurus cardiaca L. (motherwort): a review of its phytochemistry and pharmacology. Phytother Res. 2013; 27 (8):1115–20.
  64. Karomatov ID, Khalilova RS. Pustyrnik serdechnyi – izvestnoe lekarstvennoe rastenie [Motherwort warm known herb]. Biologiya i Interaktivnaya medicina. 2017;11:236–43. Russian
  65. Miłkowska-Leyck K, Filipek B, Strzelecka H. Pharmacological effects of lavandulifolioside from Leonurus cardiac. J Ethnopharmacol. 2002;80(1):85–90.
  66. Polyakov NG. Investigation into biological activity of valerian and motherwort (Leonurus) tinctures on rabbits // Farmakol Toksikol. 1962; 25: 423–7.
  67. Arushanyan EB, Hovhannesov KB, Shchurovskaya IYu. Vliyanie grandaxina i nastoiki pustyrnika na trevozhnost i svetovospriyatie u molodyh lyudei [The influence of grandaxine and tincture Lionuri on anxiety and retinal light perception]. Psychopharmacol. Biol. Narcol. 2004; 4(1): 608–11. Russian
  68. Islam A, Hussain MdS, Sen N, Abedin F, Millat NdS, Islam MS, Das A, Kar A, Hussain MdM. Investigation of in vitro thrombolytic and anti-helminthic activity and in vivo anxiolytic and antidepressant potentiality with phytochemical nature of methanolic extract of Leucas lavandulifolia. Sustainable Chemistry and Pharmacy. 2017; 6: 61–6.
  69. Abdul A, Ahmad KI. Pharmacological evaluation of Sedative and Hypnotic activities of methanolic extract of Lycopus europaeus in mice. The Journal of Phytopharmacology. 2013; 2(4): 8–12.
  70. Popova NV, Litvinenko VI. Voprosy standartizatsii lekarstvennogo rastitelnogo syrya – melissy listev [Matters of the standardization of drug – Melissa leaf]. Farmacom. 2009; 2:45–50. Russian
  71. Flora Evropeiskoi chasti SSSR [Flora of the European part of the USSR]. Pod red. Fedorova A.A. TZL.: Nauka.1978; 259 p. Russian
  72. Alekseeva AV, Mazur LI, Kurkin VA. Melissa lekarstvennaya: perspektivy ispolzovaniya v pediatricheskoi praktike [Melissa officinalis: prospects for use in pediatric practice]. Pediatriya. 2011;90(1):90–5. Russian
  73. Moradkhani H, Sargsyan E, Bibak H, Naseri B, Sadat-Hosseini M, Fayazi-Barjin A, Meftahizade H. Melissa officinalis L., a valuable medicine plant: A review. J. of Medicinal Plants Research. 2010; 4(25):2753–9.
  74. Ondrejovič M, Kraic F, Benkovičová H, Šilhár S. Optimisation of antioxidant extraction from lemon balm (Melissa officinalis). Czech J. Food Sci. 2012;30(4):385–93.
  75. Patora J, Klimek B. Flavonoids from lemon balm (Melissa officinalis L., Lamiaceae). Acta Poloniac Pharmaccutica. 2002;59(2):139–43.
  76. Voskoboinikova IV, Kolkhir VK, Mineeva MF, Strelkova LB. Fito Novo-Sed – novoe lekarstvennoe sredstvo rastitelnogo proishozhdeniya s anxioliticheskimi i sedativnymi svoistvami [Phito Novo-Sed - a new medicine of plant origine with anxiolytic and sedative properties. Problems of biological, medical and pharmaceutical chemistry. 2008;1:38–45. Russian
  77. Zuzuk BM, Kutsik RV. Melissa lekarstvennaya (Melіssa offіcіnalіs L): Analiticheskii obzor [Melissa officinalis (Melіssa offіcіnalіsL.): Analytical review]. Provizor. 2002;1:36–39. Russian
  78. Zuzuk BM, Kutsik RV. Melissa lekarstvennaya (Melіssa offіcіnalіs L): Analiticheskii obzor [Melissa officinalis (Melіssa offіcіnalіsL.): Analytical review]. Provizor. 2002; 2: 21–25. Russian
  79. Awad R, Muhammad A, Durst T, Trudeau VL, Arnason JT. Bioassay-guided Fractionation of Lemon Balm (Melissa officinalis L.) using an In Vitro Measure of GABA Transaminase Activity. Phytother. Res. 2009; 23: 1075–81.
  80. Gosudarstvennaya pharmakopeya Rossiiskoi Federatsii [State Pharmacopoeia of the Russian Federation]. In 4 Vol. [cited 2019 Dec 12]. 2018. Available from: http://femb.ru/femb/pharmacopea.php Russian
  81. Meftahizade H, Sargsyan E, Moradkhani H. Investigation of antioxidant capacity of Melissa officinalis L. essential oils. J. of Medicinal Plant Research. 1993; 4(14): 1391–5.
  82. Koksal E, Bursal E, Dikici E, Tozoglu F, Gulcin I. Antioxidant activity of Melissa officinalis leaves. J. Med. Plant. Res. 2011;5(2):217–22.
  83. Sari AO, Ceylon A. Yield characteristics and essential oil composition of lemon balm (Melissa officinalis L.) grown in the Aegean region of Turkey. Turk. J. Agric. For. 2002; 26: 217–24.
  84. Bağdat RB, Coşge B. The essential oil of lemon balm (Melissa officinalis L.), its components and using fields // J. of Fac. of Agric. 2006; 21(1): 116–21.
  85. Sharafzadeh S, Khosh-Khui M., Javidnia K. Aroma profile of leaf and stem of lemon balm (Melissa officinalis L.) Grown under Greenhouse Conditions. Advances in Environmental Biology. 2011; 5(4):547–50.
  86. Sharafzadeh S, Khosh-Khui M, Javidnia K. Effect of nutrients on essential oil components, pigments and total phenolic content of lemon balm (Melissa officinalis L.). Advances in Environmental Biology. 2011;5(4):639–46.
  87. Kurkin VA, Dubishchev AV, Ezhkov VN, Titova IN. Antidepressantnaya aktivnost nekotoryh fitopreparatov i fenilpropanoidov [Antidepressant activity of some phytopharmaceuticals and phenylpropanoids]. Pharmaceutical Chemistry Journal. 2006;40(3):33–8. Russian
  88. Oniga I, Vlase L, Toiu A, Benedec D, Duda M. Evaluation of phenolic acid derivatives and essential oil content in some Melissa officinalis L. varieties. Farmacia. 2010; 58(6):764–9. Russian
  89. Patora J, Majda T, Gora J, Klimek B. Variability in the content and composition of essential oil from lemon balm (Melissa officinalis L.) cultivated in Poland. Acta Poloniac Pharmaccutica. 2003; 60(5):395–400.
  90. Ryabinina EI, Zotova EE, Ponomareva NI, Ryabinin SV. Sravnitelnoe issledovanie melissy lekarstvennoi i shalfeya lekarstvennogo na soderzhanie polifenolov [Comparative research of the officinal balm and the officinal sage concerning the polyphenols content]. Vestnik VGU. 2009;2:49–53. Russian
  91. Koch-Heitzmann I., Schultze W. 2000 Jahre Melissa officinalis. Z. Phytotherapie. 1988;9(3):77–85.
  92. Coleta M, Campos MG, Cotrim MD, Proenca da Cunha A. Comparative evaluation of Melissa officinalis L., Tilia europaea L., Passiflora edulis Sims. and Hypericum perforatum L. in the elevated plus maze anxiety test. Pharmacopsychiatry. 2001;34(1): 20–1.
  93. Lin SH, Chou ML, Chen WC, Lai YS, Lu KH, Hao CW, Sheen LY. A medicinal herb, Melissa officinalis L. ameliorates depressive-like behavior of rats in the forced swimming test via regulating the serotonergic neurotransmitter // J Ethnopharmacol. 2015; 175: 266–72.
  94. Taiwo AE, Leite FB, Lucena GM, Barros M, Silveira D, Silva MV, Ferreira VM. Anxiolytic and antidepressant-like effects of Melissa officinalis (lemon balm) extract in rats: Influence of administration and gender. Indian J Pharmacol. 2012; 44(2): 189–92.
  95. Cases J, Ibarra A, Feuillère N, Roller M, Sukkar SG. Pilot trial of Melissa officinalis L. leaf extract in the treatment of volunteers suffering from mild-to-moderate anxiety disorders and sleep disturbances. Med J Nutrition Metab. 2011; 4(3):211–8.
  96. Ibarra A, Feuillere N, Roller M, Lesburgere E, Beracochea D. Effects of chronic administration of Melissa officinalis L. extract on anxiety-like reactivity and on circadian and exploratory activities in mice. Phytomedicine. 2010;17(6):397–403.
  97. Tokareva MG, Prozhogina YE, Kalenikova EI, Dzhavakhyan MA. Farmakognosticheskie i farmakologicheskie aspekty sozdaniya novyh sedanivnyh preparatov na osnove lekarstvennogo rastitelnogo syrya [The pharmacognostic and pharmacological aspects of the creating of the new sedative drugs based on medicinal plant medicinal raw materials]. Problems of Biological, Medical and Pharmaceutical Chemistry. 2018; 21(3):3–9. Russian
  98. Elansary HO, Ashmawy NA. Essential oils of mint between benefits and hazards. J. Essent. Oil Bear. Plants. 2013; 16:429–38.
  99. Lawrence BM. Mint – The Genus Mentha Medicinal and Aromatic Plants. Industrial Profiles. CRC Press: Boca Raton. FL. USA. 2007; 547 p.
  100. Olisaev VA, Kadieva LS. Dary lesa i ih ispolzovanie [Gifts of the forest and their use]. Ordzhonikidze; 1984. 184 p. Russian
  101. Sokolov SYa, Zamotaev IP. Spravochnik po lekarstvennym rasteniyam [Herbal Reference]. M.; 1993. 464 p. Russian
  102. Parveen T, Amin N, Saleem D, Razi F, Haider S, Haleem DJ. Antistress effect of Mentha piperita in rats and the role of brain serotonin and dopamine. Asian Journal of Pharmaceutical & Biological Research (AJPBR). 2012; 2(1): 73–8.
  103. Verma SM, Arora H, Dubey R. Anti-inflammatory and sedative-hypnotic activity of the methanolic extract of the leaves of Mentha arvensis. Ancient Science of Life. 2003; 23(2): 95–9.
  104. Anderson W, Barrows M, Lopez F, Rogers S, Ortiz-Coffie A, Norman D, Hodges J, McDonald K, Barnes D, McCall S, Don JA, Ceremuga TE. Investigation of the anxiolytic effects of naringenin, a component of Mentha aquatica, in the male Sprague-Dawley rat. Holist Nurs Pract. 2012; 26(1): 52–7.
  105. Naguib AM, Ebrahim ME, Aly HF, Metawaa HM, Mahmoud AH, Mahmoud EA, Ebrahim FM. Phytochemical screening of Nepeta cataria extracts and their in vitro inhibitory effects on free radicals and carbohydrate-metabolising enzymes. Nat Prod Res. 2012; 26 (23): 2196–8.
  106. Rabbani M, Sajjadi SE, Mohammadi A. Evaluation of the Anxiolytic Effect of Nepeta persica Boiss. in Mice. Evidence-Based Complementary and Alternative Medicine. 2008; (2):181–6.
  107. Aydin S, Beis R, Ozturk Y, Baser KH. Nepetalactone: a new opioid analgesic from Nepeta caesarea Boiss. J Pharm Pharmacol. 1998;50:813–7.
  108. Chiej R. The McDonald Encyclopedia of Medicinal Plants. London: McDonald and Co Ltd.; 1998. 204 p.
  109. Harney JW, Barofsky IM, Leary JD. Behavioral and toxicological studies of cyclopentanoid monoterpenes from Nepeta cataria. Lloydia. 1978; 41: 367.
  110. Sherry CJ, Hunter PS. The effect of an ethanol extract of catnip (Nepeta cataria) on the behavior of the young chick. Experientia. 1979; 35: 237.
  111. Formisano C, Rigano D, Senatore F. Chemical Constituents and Biological Activities of Nepeta Species. Chemistry & Biodiversity. 2011; 8(10): 1783–818.
  112. Hosseini A, Forouzanfar F, Rakhshandeh H. Hypnotic Effect of Nepeta glomerulosa on Pentobarbital-Induced Sleep in Mice. Jundishapur J Nat Pharm Prod. 2016;11 (1):25063.
  113. Kolouri S, Firoozabadi A, Salehi A, Zarshenas MM, Dastgheib SA, Heydari M, Rezaeizadeh H. Nepeta menthoides Boiss. & Buhse freeze-dried aqueous extract versus sertraline in the treatment of major depression: A double blind randomized controlled trial. Complementary Therapies in Medicine. 2016; 26:164–70.
  114. Pisarev DI, Sevruk IA, Malyutina AYu, Krikun EN, Novikova MYu, Guryev IV. Issledovanie sostava antotsyanov travy Ocimum basilicum L. v ramkah nauchnogo napravleniya «Farmatsevticheskii remeik» [The study of ocimum basilicum L. herb anthocyanins within the “Pharmaceutical remake” scientific field]. Nauchnye resultaty biomeditsinskih issledovanii. 2016; 2(2):44–9. Russian
  115. Rabbani M, Sajjadi SE, Vaezi A. Evaluation of anxiolytic and sedative effect of essential oil and hydroalcoholic extract of Ocimum basilicum L. and chemical composition of its essential oil. Res Pharm Sci. 2015; 10(6): 535–43.
  116. Neamati A, Talebi S, Hosseini M, Boskabady MH, Beheshti F. Administration of Ethanolic Extract of Ocimum basilicum Leaves Attenuates Depression Like Behavior in the Rats Sensitized by Ovalbumin. Current Nutrition & Food Science. 2016; 12(1): 72–8.
  117. Okoli CO, Ezike AC, Agwagah OC, Akah PA. Anticonvulsant and anxiolytic evaluation of leaf extracts of Ocimum gratissimum, a culinary herb. Pharmacognosy Res. 2010;2(1):36–40.
  118. Tankam JM, Ito M. Sedative, anxiolytic and antidepressant-like effects of inhalation of the essential oil of Ocimum gratissimum L. from Cameroon in mice. Journal of Pharmacognosy and Phytochemistry. 2014;2 (5):1–9.
  119. Orafidiya LO, Agbani EO, Iwalewa EO, Adelusola KAA, Oyedapo OO. Studies on the acute and sub-chronic toxicity of the essential oil of Ocimum gratissimum L. leaf. Phytomedicine. 2004; 11: 71–6.
  120. Kumari R, Agrawal A, Dubey GP. Role of medicinal plants with antidepressant action and its mechanism: a review. Pharmaceutical and Biological Evalutions. 2016; 3(1):70–82.
  121. Ravindran R, Rathinasamy SD, Samson J, Senthilvelan M. Noisestress-induced brain neurotransmitter changes and the effect of Ocimum sanctum (Linn) treatment in albino rats. J Pharmacol Sci. 2005; 98 (4): 354–60.
  122. Maity TK, Mandal S, Saha B, Madhumangal P. Effect of Ocimum sanctum roots extract on swimming performance in mice. Phytotherapy research. 2000; 14 (2):120–1.
  123. Jothie RE, Illuri R, Bethapudi B, Anandhakumar S, Bhaskar A, Chinampudur Velusami C, Mundkinajeddu D, Agarwal A. Anti-stress Activity of Ocimum sanctum: Possible Effects on Hypothalamic-Pituitary-Adrenal Axis. Phytotherapy Research. 2016; 30: 805–14.
  124. Tepe B, Cakir A, Sihoglu Tepe A. Medicinal Uses, Phytochemistry, and Pharmacology of Origanum onites (L.): A Review. Chem. Biodiversity. 2016; 13:504–20.
  125. Mombeini T, Mazloumi S, Shams J. Pharmacological Effects of Origanum vulgare L. in the Elevated Plus-Maze and Open Field Tests in the Rat. Journal of Basic and Clinical Pathophysiology. 2015;3(2):29–36.
  126. Rezaie A, Jafari B, Mousavi G, Nazeri M, Ebadi A, Ahmadeh C, Habibi E. Comparative Study of Sedative, Pre-Anesthetic and Anti-Anxiety Effect of Origanum majorana Extract with Diazepam on Rats. Research Journal of Biological Science. 2011; 6(11):611–4.
  127. Tsuji M, Miyagawa K, Takeuchi T, Takeda H. Pharmacological characterization and mechanisms of the novel antidepressive- and/or anxiolytic-like substances identified from Perillae Herba. Nihon Shinkei Seishin Yakurigaku Zasshi. 2008; 28 (4):159–67.
  128. Ribeiro-Santos R, Carvalho-Costa D, Cavaleiro C, Costa HS, Gonçalves Albuquerque T, Castilho MC. A novel insight on an ancient aromatic plant: the rosemary (Rosmarinus officinalis L.). Trends Food Sci. Technol. 2015; 45: 355–68.
  129. Begum A, Sandhya S, Vinod KR, Reddy S, Banji D. An in-depth review on the medicinal flora Rosmarinus officinalis (Lamiaceae). Acta Sci. Pol. Technol. Aliment. 2013; 12: 61–73.
  130. Abdelhalim A, Karim N, Chebib M, Aburjai T, Khan I, Johnston GA, Hanrahan J. Antidepressant, anxiolytic and antinociceptive activities of constituents from Rosmarinus officinalis. J. Pharm. Pharm. Sci. 2015; 18(4): 448–59.
  131. Noori AAM, Mortazavi M, Kalani N, Marzouni HZ, Kooti W, Ali-Akbari S. Effect of Hydroalcoholic Extract of Rosmarinus officinalis L. Leaf on Anxiety in Mice. J Evid Based Complementary Altern Med. 2016; 21(4): 85–90.
  132. Miraj S. An evidence-based review on remedies of Rosmarinus officinalis. Pharm. Lett. 2016; 8: 426–36.
  133. Baykova EV. Rod shafei: morfologia, evolutsiya, perspectivy introduktsii [Sage genus: morphology, evolution, perspectives of introduction]. Novosibirsk: Nauka; 2006. 248 p. Russian
  134. Ryabinina EI, Zotova EE, Vetrova EN, Ponomareva NI. Sravnenie himiko-analiticheskih metodov opredeleniya tanidov i antioxidantnoi aktivnosti rastitelnogo syrya [The comparison chemical analytical methods of determination of tanides and antioxidation activity of plant medicinal raw materials]. Analitika i control. 2011; 15(2):202–8. Russian
  135. Rutherford DM, Nielsen MP, Hansen SK, Witt MR, Bergendorff O, Stemer O. Isolation and identification from Salvia officinalis of two diterpenes which inhibit t-butylbicyclophosphoro-[35S]-thionate binding to chloride channel of rat cerebrocortical membranes in vitro. Neurosci Lett. 1992; 135: 224–6.
  136. Jäger AK, Krydsfeldt K, Rasmussen HB. Bioassay-guided isolation of apigenin with GABA-benzodiazepine activity from Tanacetum parthenium. Phytother. Res. 2009; 23: 1642–4.
  137. Fernändez S, Wasowski C, Paladini AC, Marder M. Sedative and sleep-enhancing properties of linarin, a flavonoid-isolated from Valeriana officinalis. Pharmacol. Biochem. Behav. 2004; 77: 399–404.
  138. Kavvadias D, Sand P, Youdim KA, Qaiser MZ, Rice-Evans C, Baur R, Sigel E, Rausch WD, Riederer P, Schreier P. The flavone hispidulin, a benzodiazepine receptor ligand with positive allosteric properties, traverses the blood-brain barrier and exhibits anticonvulsive effects. Br J Pharmacol. 2004;142 (5):811–20.
  139. Kavvadias D, Monschein V, Sand P, Riederer P, Schreier P. Constituents of sage (Salvia officinalis) with in vitro affinity to human brain benzodiazepine receptor. Planta Med. 2003; 69: 113–7.
  140. Kaibova SR, Dayronas JV, Zilfikarov IN. Perspektivy ispolzovaniya vidov semeistva Lamiaceae flory Dagestana v medicine [Prospects for the use of species of the family Lamiaceae of the flora of Dagestan in medicine]. Sb. mater. 24-go Nats. Kongressa «Сhelovek i lekarstvo». Tezisy dokl. M.Vidox; 2017. 142 p. Russian
  141. Lu Y, Foo Y. Polyphenolics of Salvia – a review. Phytochemistry. 2002; 59:117–40.
  142. González-Cortazar M, Maldonado-Abarca AM, Jiménez-Ferrer E, Marquina S, Ventura-Zapata E, Zamilpa A, Tortoriello J, Herrera-Ruiz M. Isosakuranetin-5-O-rutinoside: a new flavanone with antidepressant activity isolated from Salvia elegans Vahl. Molecules. 2013; 18 (11): 13260–70.
  143. Herrera-Ruiz M, García-Beltrán Y, Mora S, Díaz-Víliz G, Viana GSB, Tortoriello J, Ramírez G. Antidepressant and anxiolytic effects of hydroalcoholic extract from Salvia elegans. Journal of Ethnopharmacology. 2006; 107(1):53–8.
  144. Rabbani M, Sajjadi SE, Jafarian A, Vaseghi G. Anxiolytic effects of Salvia reuterana Boiss. on the elevated plus-maze model of anxiety in mice. Journal of Ethnopharmacology. 2005; 101(1–3): 100–3.
  145. Javdan N, Estakhr J. Neuropharmacological and antidiarrhoeal activity of ethanolic extract of salvia hypoleuca in rat. Pharmacology online. 2011; 2: 905–10.
  146. Hosseinzadeh H, Hassanzadeh AR. Muscle relaxant and hypnotic effects of Salvia leriifolia Benth. leaves extract in mice. Iran J Basic Med Sci. 2001; 4: 3(11): 130–8.
  147. Atanasova-Shopova S, Rusinov K. Effects of the Salvia sclarea essential oil on the central nervous system. Izv Inst Fiziol. 1970;13:89–95.
  148. Salah SM, Jager AK. Screening of traditionally used Lebanese herbs for neurological activities. J Ethnopharmacol. 2005; 97: 145–9.
  149. Marder M, Viola H, Wasowski C, Wolfman C, Waterman PG, Medina JH, Paladini AC. Cirsiliol and caffeic acid ethyl ester, isolated from Salvia guaranitica, are competitive ligands for the central benzodiazepine receptors. Phytomedicine. 1996; 3 (1): 29–31.
  150. Viola H, Wasowski C, Marder M, Wolfman C, Paladini AC, Medina JH. Sedative and hypnotic properties of Salvia guaranitica St. Hil. and of its active principle, Cirsiliol. Phytomedicine. 1997;4 (1):47–52.
  151. Akbar S, Tariq M, Nisa M. A study on CNS depressant activity of Salvia haematodes Wall. Int J Crude Drug Res. 1984;22:41–4.
  152. Imanshahidi M, Hosseinzadeh H. The pharmacological effects of Salvia species on the central nervous system. The Phytotherapy research. 2006;20 (6):427–37.
  153. Chang HM, Chui KY, Tan FW, Yang Y, Zhong ZP, Lee CM, Sham HL, Wong HN. Structure-activity relationship of miltirone, an active central benzodiazepine receptor ligand isolated from Salvia miltiorrhiza Bunge (Danshen). J Med Chem. 1991; 34: 1675–92.
  154. Lee CM, Wong HN, Chui KY, Choang TF, Hon PM, Chang HM. Miltirone, a central benzodiazepine receptor partial agonist from a Chinese medicinal herb Salvia miltiorrhiza. Neurosci Lett. 1991; 127: 237–41.
  155. Johnston GA, Beart PM. Flavonoids: some of the wisdom of sage? Br. J. Pharmacol. 2004; 142: 809–10.
  156. Fierascu I, Dinu-Pirvu CE, Fierascu RC, Velescu BS, Anuta V, Ortan A, Jinga V. Phytochemical Profile and Biological Activities of Satureja hortensis L.: A Review of the Last Decade. Molecules. 2018; 23 (10): 2458.
  157. Fatemeh M, Masoumeh AR. Anxiolitic and antidepressant effects of summer savory (Satureja hortensis) hydroalcoholic extract in male rats exposed to chronic restraint stress. Daneshvar medicine. 2016;24(125):31–8.
  158. Melo FH, Venâncio ET, de Sousa DP, de França Fonteles MM, de Vasconcelosa SM, Viana GS, de Sousa FC. Anxiolytic-like effect of Carvacrol (5-isopropyl-2-methylphenol) in mice: involvement with GABAergic transmission. Fundamental & Clinical Pharmacology. 2010; 24: 437–43.
  159. Razuvaeva YaG, Kharzheev DV, Toropova AA, Olennikov DN. Stress-protektivnoe i antioxidantnoe deistvie extrakta suhogo Schizonepeta multifida (L.) Briq. [The stress-protective and antioxidant effect of the schizonepeta multifida (l.) Briq. dry extract]. Problems of Biological, Medical and Pharmaceutical Chemistry. 2018; 21(7): 5–10. Russian
  160. Razuvaeva YaG, Kharzheev DV, Garmaev DE. Fitoterapiya trevozhnyh rasstroistv [Phytotherapy of anxiety disorders]. Vestnik Buryatskogo gosudarstvennogo universiteta. Medicina i farmatsiya. 2015; 12: 91–5. Russian
  161. Karimov A, Yuldashev MP, Botirov EKh. Flavonoidy Scutellaria adenostegia Briq. [Flavonoids of scutellaria adenostegia Briq]. Chemistry of plant medicinal raw material. 2015;1:63–8. Russian
  162. Kim VE, Pravdyuk MF, Konovalov DA. Hromato-mass-spectrometricheskoe issledovanie fitoekstracta na osnove travy pustyrnika, kornei shlemnika baikalskogo, kornevisch s kornyami sinyuhi goluboi [GH/MS research of phytoextract on the basis of a grass of a motherwort, roots of a baikal skullcap, rhizomes with roots of a jacob’s ladder]. Vestnik VGU, Seria: Himiya, Biologiya, Farmatsiya. 2015;1:129–31. Russian
  163. Gilhotra N, Dhingra D. A review on antianxiety plants. Natural product radiance. 2008; 7(5): 476–83.
  164. Hui KM, Huen MS, Wang HY, Zheng H, Sigel E, Baur R, Ren H, Li ZW, Wong JT, Xue H. Anxiolytic effect of wogonin, a benzodiazepine receptor ligand isolated from Scutellaria baicalensis Georgi. Biochem Pharmacol. 2002; 64 (9): 1415–24.
  165. Lee H, Kim YO, Kim H, Kim SY, Noh HS, Kang SS, Cho GJ, Choi WS, Suk K. Flavonoid wogonin from medicinal herb is neuroprotective by inhibiting inflammatory activation of microglia. FASEB J. 2003; 17(13): 1943–4.
  166. Li J, Wang YH, Smillie TJ, Khan IA. Identification of phenolic compounds from Scutellaria lateriflora by liquid chromatography with ultraviolet photodiode array and electrospray ionization tandem mass spectrometry. J Pharm Biomed Anal. 2012; 7 (63): 120–7.
  167. De Carvalho RS, Duarte FS, de Lima TC. Involvement of GABAergic non-benzodiazepine sites in the anxiolytic-like and sedative effects of the flavonoid baicalein in mice. Behav Brain Res. 2011; 221 (1): 75–82.
  168. Metzman HL. Monograph of Scutellaria lateriflora. Journal of the American ists Guild. 2006; 7(1):4–18.
  169. Duru ME, Cakir A, Harmandar M, Izumi S, Hirata T. The volatile constituents of Stachys athorecalyx C. Kotch. from Turkey. Flavour Fragr. J. 1999; 14: 12–4.
  170. Javidnia K, Mojabb F, Mojahedi SA. Chemical constituents of the essential oil of Stachys lavandulifolia Vahl. from Iran. Iran. J. Pharm. Res. 2004;3:61–3.
  171. Kumar D, Bhat ZA. Apigenin 7-glucoside from Stachys tibetica Vatke and its anxiolytic effect in rats. 2014; 21(7): 1010–4.
  172. Kartsev VG, Stepanichenko NN, Auelbekov SA. Chemical composition and pharmacological properties of plants of the genus Stachys. Chemistry of Natural Compounds. 1994; 30(6): 645–54.
  173. Rabbani M, Sajjadi SE, Jalali A. Hydroalcohol Extract and Fractions of Stachys lavandulifolia Vahl: Effects on Spontaneous Motor Activity and Elevated Plus-maze Behaviour. Phytother. Res. 2005; 19: 854–8.
  174. Rabbani M, Sajjadi SE, Zarei HR. Anxiolytic effects of Stachys lavandulifolia Vahl on the elevated plus-maze model of anxiety in mice. Journal of Ethnopharmacology. 2003; 89: 271–6.
  175. Kumar D, Bhat ZA, Kumar V, Raja WY, Shah MY. Anti-anxiety activity of Stachys tibetica Vatke. Chinese Journal of Natural Medicines. 2013; 11 (3): 240–4.
  176. Kumar D, Bhat ZA, Kumar V, Khan NA, Chashoo IA, Zargar MI, Shah MY. Effects of Stachys tibetica essential oil in anxiety. European Journal of Integrative Medicine. 2012;4(2):169–76.
  177. Savić MM, Kukić JM, Grayer RJ, Milinković MM, Marin PD, Divljaković J, Van Linn M, Cook JM, Petrović SD. Behavioural characterization of four endemic Stachys taxa. Phytother Res. 2010; 24 (9): 1309–16.
  178. Uhl SR. Handbook of Spices, Seasonings, and Flavorings. Chapter 4. Lancaster: Technomic Publishing Co Inc.; 2000. 329 p.
  179. Komaki A, Hoseini F, Shahidi S, Baharloue N. Study of the effect of extract of Thymus vulgaris on anxiety in male rats. Journal of Traditional and Complementary Medicine. 2016; 6:257–61.
  180. Bhandari SS, Kabra MP. To evaluate anti-anxiety activity of thymol. Journal of Acute Disease. 2014;3(2):136–40.
  181. Morteza-Semnani K, Mahmoudi M, Riachi G. Effects of Essential Oils and Extracts from Certain Thymus. Species on Swimming Performance in Mice. Pharmaceutical Biology. 2007;45(6):464–7.

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