RESEARCH OF UV-PROTECTIVE ACTIVITY OF FERULIC ACID AS PART OF OINTMENT COMPOSITIONS WITH DIFFERENT PHYSICAL AND CHEMICAL PROPERTIES


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Cosmetics with the ability to neutralize harmful influence of ultraviolet rays on skin are quite in demand. UV filters in creams composition are divided into two groups: physical and chemical. Antioxidants are used as chemical UV filters. The article presents the results of ferulic acid testing as UV filter in ointment bases with lipophile, hydrophile and lipophilic and hydrophilic properties. The dependence of ferulic acid efficiency from the base type where it was applied was established. The results received are correlated with data about release rate of ferulic acid received in vitro. Ointment bases with such emulsifiers as cetyl alcohol, base emulsifier and Olivem 1000 have the most signified UV protective effect of ferulic acid.

作者简介

I. Abisalova

Pyatigorsk Medical and Pharmaceutical Institute - a branch of Volgograd State Medical University

Email: iraabi@yandex.ru

E. Fyodorova

Pyatigorsk Medical and Pharmaceutical Institute - a branch of Volgograd State Medical University

Email: Felp15@yandex.ru

E. Maslovskaya

Pyatigorsk Medical and Pharmaceutical Institute - a branch of Volgograd State Medical University

Email: Maslovskaya.EK@yandex.ru

参考

  1. Назарова, Л.Е. Активность кислоты феруловой в условиях цитотоксического повреждения / Л.Е. Назарова, М.А. Оганова, И.Л. Абисалова. - Пятигорск: ООО РИА на КМВ, 2010. - 115 с.
  2. Назарова Л.Е., Абисалова И.Л., Оганова М.А. Исследование влияния кислоты феруловой на резистентность мембран эритроцитов в условиях окислительного стресса // Известия Самарского научного центра РАН. 2013. Т.15, №3(6). С. 1888-1890.

版权所有 © Abisalova I.L., Fyodorova E.P., Maslovskaya E.A., 2014

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