ANALGETIC ACTIVITY OF SUBSTITUTED 1-(2-IMIDAZOLETHYL)-3- PYRROLINE-2-ONS
- Authors: Ponomaryova A.A1, Yurchenko A.S1, Kasimova N.N1
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Affiliations:
- Perm State Pharmaceutical Academy, Perm
- Issue: Vol 2, No 6 (2014)
- Pages: 99-101
- Section: Articles
- URL: https://journals.rcsi.science/2307-9266/article/view/111386
- ID: 111386
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Abstract
The article presents the review of initial stage of carried out studies of an analgetic activity of substituted 1-(2-imidazolethyl)-3-pyrroline-2-ons. We have established that compound marked with laboratory cipher as GKN-1165 at a dose of 50 mg/kg has analgetic activity close to the activity of ethanol of nimesulid comparison taken at the same dose.
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##article.viewOnOriginalSite##About the authors
A. A Ponomaryova
Perm State Pharmaceutical Academy, Perm
Email: anny.yurg@mail.ru
A. S Yurchenko
Perm State Pharmaceutical Academy, Perm
N. N Kasimova
Perm State Pharmaceutical Academy, Perm
References
- Руководство по экспериментальному (доклиническому) изучению новых фармакологических веществ / Под общей редакцией члена-кореспондента РАМН, профессора Р.У. Хабриева. - 2 изд., перераб. и доп. - М.:ОАО «Издательство «Медицина», 2005. - 832с.
- Зайцев А. А. Фармакология болеутоляющих средств в эксперименте и клинике. - Л., 1991. - С. 69.
