Статины и сахарный диабет: фокус на питавастатин

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Обзор посвящен проблеме развития нарушений углеводного обмена у пациентов, длительно принимающих статины. Проанализированы данные рандомизированных клинических исследований, метаанализов и экспериментальных работ, свидетельствующие о наличии диабетогенного эффекта у большинства статинов. Представлены возможные механизмы влияния терапии статинами на обмен углеводов. Особое внимание уделено месту питавастатина в контексте данной проблемы в связи с его низкой диабетогенностью и минимальным риском лекарственных взаимодействий, а также необходимости учета риск-факторов развития диабета у больных, получающих терапию статинами, и возможности его предотвращения.

Об авторах

Сорейя Асафовна Уразгильдеева

ФГБОУ ВО «Санкт-Петербургский государственный университет»; Центр клинической липидологии Центра сердечной медицины «Черная Речка»; ФГБУЗ «Клиническая больница №122 им. Л.Г. Соколова» ФМБА России

Автор, ответственный за переписку.
Email: docsau64@yandex.ru

д-р мед. наук, вед. науч. сотр. отд. атеросклероза НКиОЦ «Кардиология» ФГБОУ ВО СПбГУ, рук. Центра клинической липидологии Центра сердечной медицины «Черная Речка», кардиолог-консультант Центра атеросклероза и нарушений липидного обмена ФГБУЗ «КБ №122 им. Л.Г. Соколова»

Россия, Санкт-Петербург

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