Immunity against Mycobacterium tuberculosis: Defense strategies
- Авторы: Rozov S.M.1,2, Popova N.A.2, Deineko E.V.1,3
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Учреждения:
- Institute of Cytology and Genetics, Siberian Branch
- Novosibirsk State University
- Tomsk State University
- Выпуск: Том 6, № 6 (2016)
- Страницы: 483-496
- Раздел: Article
- URL: https://journals.rcsi.science/2079-0864/article/view/206338
- DOI: https://doi.org/10.1134/S2079086416060062
- ID: 206338
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Аннотация
Mycobacterium tuberculosis (Mtb) is an intracellular pathogen that mainly affects alveolar macrophages. We have still no satisfactory vaccine against tuberculosis, and more than one-third of the global population are carriers of this pathogen. For the development of a vaccine that would induce not only humoral but, particularly, cell-mediated immunity, we must know all of the processes involved in the interaction between elements of the immune system and Mtb at all stages of the disease. This review considers the responses of immune system elements to various factors used by Mtb for cell invasion, survival, and reproduction.
Об авторах
S. Rozov
Institute of Cytology and Genetics, Siberian Branch; Novosibirsk State University
Автор, ответственный за переписку.
Email: rozov@bionet.nsc.ru
Россия, Novosibirsk; Novosibirsk
N. Popova
Novosibirsk State University
Email: rozov@bionet.nsc.ru
Россия, Novosibirsk
E. Deineko
Institute of Cytology and Genetics, Siberian Branch; Tomsk State University
Email: rozov@bionet.nsc.ru
Россия, Novosibirsk; Tomsk
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